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Literature DB >> 20130964

microRNAs and lung cancer: tumors and 22-mers.

Abstract

Work over the last decade has revealed novel regulatory mechanisms in pathological disease states that are mediated by microRNAs and has inspired researchers to begin elucidating the specific roles of miRNAs in the regulation of genes involved in cancer development and progression. Recently, miRNAs have been explored as therapeutic targets and diagnostic markers of cancer. In this paper, we review recent advances in the study of miRNAs involved in tumorigenesis, focusing on miRNA regulation of genes that have been demonstrated to play critical roles in lung cancer development. We discuss miRNA regulation of genes that play critical roles in the process of malignant transformation, angiogenesis and tumor metastasis, the dysregulation of miRNA expression in cancer development, and the development of miRNA-based diagnostics and therapeutics.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
MicroRNAs

Year: 2010 PMID： 20130964 PMCID： PMC2884965 DOI： 10.1007/s10555-010-9204-9

Source DB: PubMed Journal: Cancer Metastasis Rev ISSN： 0167-7659 Impact factor: 9.264

145 in total

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Authors: Susana Gonzalo; Isabel Jaco; Mario F Fraga; Taiping Chen; En Li; Manel Esteller; María A Blasco
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2. Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.

Authors: Aaron P Jansen; Corinne E Camalier; Nancy H Colburn
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3. miR-15a and miR-16-1 down-regulation in pituitary adenomas.

Authors: Arianna Bottoni; Daniela Piccin; Federico Tagliati; Andrea Luchin; Maria Chiara Zatelli; Ettore C degli Uberti
Journal: J Cell Physiol Date: 2005-07 Impact factor: 6.384

4. Extensive modulation of a set of microRNAs in primary glioblastoma.

Authors: S A Ciafrè; S Galardi; A Mangiola; M Ferracin; C-G Liu; G Sabatino; M Negrini; G Maira; C M Croce; M G Farace
Journal: Biochem Biophys Res Commun Date: 2005-09-09 Impact factor: 3.575

5. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.

Authors: Nozomu Yanaihara; Natasha Caplen; Elise Bowman; Masahiro Seike; Kensuke Kumamoto; Ming Yi; Robert M Stephens; Aikou Okamoto; Jun Yokota; Tadao Tanaka; George Adrian Calin; Chang-Gong Liu; Carlo M Croce; Curtis C Harris
Journal: Cancer Cell Date: 2006-03 Impact factor: 31.743

6. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma.

Authors: Aaron J Schetter; Suet Yi Leung; Jane J Sohn; Krista A Zanetti; Elise D Bowman; Nozomu Yanaihara; Siu Tsan Yuen; Tsun Leung Chan; Dora L W Kwong; Gordon K H Au; Chang-Gong Liu; George A Calin; Carlo M Croce; Curtis C Harris
Journal: JAMA Date: 2008-01-30 Impact factor: 56.272

Review 7. Angiogenesis in the treatment of non-small cell lung cancer.

Authors: Leora Horn; Alan B Sandler
Journal: Proc Am Thorac Soc Date: 2009-04-15

8. Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23).

Authors: J Whang-Peng; C S Kao-Shan; E C Lee; P A Bunn; D N Carney; A F Gazdar; J D Minna
Journal: Science Date: 1982-01-08 Impact factor: 47.728

9. Suppression of non-small cell lung tumor development by the let-7 microRNA family.

Authors: Madhu S Kumar; Stefan J Erkeland; Ryan E Pester; Cindy Y Chen; Margaret S Ebert; Phillip A Sharp; Tyler Jacks
Journal: Proc Natl Acad Sci U S A Date: 2008-02-28 Impact factor: 11.205

10. Dicer is essential for mouse development.

Authors: Emily Bernstein; Sang Yong Kim; Michelle A Carmell; Elizabeth P Murchison; Heather Alcorn; Mamie Z Li; Alea A Mills; Stephen J Elledge; Kathryn V Anderson; Gregory J Hannon
Journal: Nat Genet Date: 2003-10-05 Impact factor: 38.330

30 in total

1. Pharmacogenomic Discovery Delineating the Genetic Basis of Drug Response.

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Journal: Curr Genet Med Rep Date: 2013-09-01

Review 2. Molecular biology of lung cancer: clinical implications.

Authors: Jill E Larsen; John D Minna
Journal: Clin Chest Med Date: 2011-10-07 Impact factor: 2.878

3. Preneoplasia of lung cancer.

Authors: Adi F Gazdar; Elisabeth Brambilla
Journal: Cancer Biomark Date: 2010 Impact factor: 4.388

4. Expression of miRNAs in non-small-cell lung carcinomas and their association with clinicopathological features.

Authors: Elham Tafsiri; Mojtaba Darbouy; Mohammad B Shadmehr; Anna Zagryazhskaya; Javad Alizadeh; Morteza Karimipoor
Journal: Tumour Biol Date: 2014-11-11

5. Lin-28 reactivation is required for let-7 repression and proliferation in human small cell lung cancer cells.

Authors: Lin Pan; Zhaohui Gong; Zhiwei Zhong; Zhuo Dong; Qiong Liu; Yanping Le; Junming Guo
Journal: Mol Cell Biochem Date: 2011-05-07 Impact factor: 3.396

Review 6. The emerging role of microRNAs in drug responses.

Authors: Wei Zhang; M Eileen Dolan
Journal: Curr Opin Mol Ther Date: 2010-12

7. MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition.

Authors: Jing Li; Sheng Yang; Wen Yan; Jie Yang; Yu-Juan Qin; Xiao-Lin Lin; Rao-Ying Xie; Sheng-Chun Wang; Wen Jin; Fei Gao; Jun-Wen Shi; Wen-Tao Zhao; Jun-Shuang Jia; Hong-Fen Shen; Jie-Rong Ke; Bin Liu; Yi-Qiao Zhao; Wen-Hua Huang; Kai-Tai Yao; Dan-Juan Li; Dong Xiao
Journal: Lab Invest Date: 2015-06-22 Impact factor: 5.662

8. Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells.

Authors: Sichuan Xi; Maocheng Yang; Yongguang Tao; Hong Xu; Jigui Shan; Suzanne Inchauste; Mary Zhang; Leandro Mercedes; Julie A Hong; Mahadev Rao; David S Schrump
Journal: PLoS One Date: 2010-10-29 Impact factor: 3.240

9. MicroRNA-100 is a potential molecular marker of non-small cell lung cancer and functions as a tumor suppressor by targeting polo-like kinase 1.

Authors: Jing Liu; Kai-Hua Lu; Zhi-Li Liu; Ming Sun; Wei De; Zhao-Xia Wang
Journal: BMC Cancer Date: 2012-11-14 Impact factor: 4.430

10. Reconfigurable hybrid interface for molecular marker diagnostics and in-situ reporting.

Authors: Kristina Ehrhardt; Michael T Guinn; Tyler Quarton; Michael Q Zhang; Leonidas Bleris
Journal: Biosens Bioelectron Date: 2015-07-17 Impact factor: 10.618