Literature DB >> 20129244

IDH1 mutations in gliomas: when an enzyme loses its grip.

Christian Frezza1, Daniel A Tennant, Eyal Gottlieb.   

Abstract

The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studying isocitrate dehydrogenase (IDH) mutations since their discovery just over a year ago. In a recent study published in Nature, Dang et al. identified 2-hydroxyglutarate as a product of tumor-associated IDH mutants with potential oncogenic activities. Copyright (c) 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20129244     DOI： 10.1016/j.ccr.2009.12.031

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  28 in total

1.  Preface to the column "Metabolism of Childhood Cancer".

Authors:  Dinesh Rakheja
Journal:  Transl Pediatr       Date:  2015-01

2.  Untargeted and stable isotope-assisted metabolomic analysis of MDA-MB-231 cells under hypoxia.

Authors:  Jie Yang; Jianhua Cheng; Bo Sun; Haijing Li; Shengming Wu; Fangting Dong; Xianzhong Yan
Journal:  Metabolomics       Date:  2018-02-27       Impact factor: 4.290

3.  Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans.

Authors:  Sider Penkov; Damla Kaptan; Cihan Erkut; Mihail Sarov; Fanny Mende; Teymuras V Kurzchalia
Journal:  Nat Commun       Date:  2015-08-20       Impact factor: 14.919

4.  R132 mutations in canine isocitrate dehydrogenase 1 (IDH1) lead to functional changes.

Authors:  Shota Kawakami; Kazuhiko Ochiai; Daigo Azakami; Yuiko Kato; Masaki Michishita; Masami Morimatsu; Toshina Ishiguro-Oonuma; Eri Onozawa; Masami Watanabe; Toshinori Omi
Journal:  Vet Res Commun       Date:  2017-12-29       Impact factor: 2.459

5.  Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.

Authors:  Giuseppe Lombardi; Giuseppe Corona; Luisa Bellu; Alessandro Della Puppa; Ardi Pambuku; Pasquale Fiduccia; Roberta Bertorelle; Marina Paola Gardiman; Domenico D'Avella; Giuseppe Toffoli; Vittorina Zagonel
Journal:  Oncologist       Date:  2015-04-10

6.  DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma.

Authors:  Brock C Christensen; Ashley A Smith; Shichun Zheng; Devin C Koestler; E Andres Houseman; Carmen J Marsit; Joseph L Wiemels; Heather H Nelson; Margaret R Karagas; Margaret R Wrensch; Karl T Kelsey; John K Wiencke
Journal:  J Natl Cancer Inst       Date:  2010-12-16       Impact factor: 13.506

7.  IDH1 and IDH2: not your typical oncogenes.

Authors:  Zachary J Reitman; D Williams Parsons; Hai Yan
Journal:  Cancer Cell       Date:  2010-03-16       Impact factor: 31.743

8.  Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase.

Authors:  Juliya Kalinina; Jun Ahn; Narra S Devi; Liya Wang; Yuancheng Li; Jeffrey J Olson; Michael Glantz; Thomas Smith; Ella L Kim; Alf Giese; Randy L Jensen; Clark C Chen; Bob S Carter; Hui Mao; Miao He; Erwin G Van Meir
Journal:  Clin Cancer Res       Date:  2016-06-23       Impact factor: 12.531

Review 9.  IDH mutations in human glioma.

Authors:  Won Kim; Linda M Liau
Journal:  Neurosurg Clin N Am       Date:  2012-05-31       Impact factor: 2.509

10.  Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation.

Authors:  Kimberly N Grelli; Amy M Palubinsky; A Cozette Kale; Britney N Lizama-Manibusan; Jeannette N Stankowski; Ginger L Milne; Robert Singer; Bethann McLaughlin
Journal:  CNS Neurol Disord Drug Targets       Date:  2013-09       Impact factor: 4.388
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