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Literature DB >> 20126330

Eslicarbazepine acetate: a well-kept secret?

Elinor Ben-Menachem.

Abstract

Entities: Chemical

Year: 2010 PMID： 20126330 PMCID： PMC2812714 DOI： 10.1111/j.1535-7511.2009.01337.x

Source DB: PubMed Journal: Epilepsy Curr ISSN： 1535-7511 Impact factor: 7.500

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8 in total

Review 1. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes.

Authors: Tracy Glauser; Elinor Ben-Menachem; Blaise Bourgeois; Avital Cnaan; David Chadwick; Carlos Guerreiro; Reetta Kalviainen; Richard Mattson; Emilio Perucca; Torbjorn Tomson
Journal: Epilepsia Date: 2006-07 Impact factor: 5.864

2. Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.

Authors: J Benes; A Parada; A A Figueiredo; P C Alves; A P Freitas; D A Learmonth; R A Cunha; J Garrett; P Soares-da-Silva
Journal: J Med Chem Date: 1999-07-15 Impact factor: 7.446

3. Eslicarbazepine acetate: a double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures.

Authors: Christian Elger; Meir Bialer; Joyce A Cramer; Joana Maia; Luis Almeida; Patrício Soares-da-Silva
Journal: Epilepsia Date: 2007-02-21 Impact factor: 5.864

4. Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment.

Authors: Luis Almeida; J Hendrick Potgieter; Joana Maia; M Alida Potgieter; Fernando Mota; P Soares-da-Silva
Journal: Eur J Clin Pharmacol Date: 2007-12-21 Impact factor: 2.953

5. Oxcarbazepine and adverse events: impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy.

Authors: Andrea Ortenzi; Aldo Paggi; Nicoletta Foschi; Debirah Sabbatini; Emore Pistoli
Journal: Funct Neurol Date: 2008 Apr-Jun

Review 6. Eslicarbazepine acetate.

Authors: Paul L McCormack; Dean M Robinson
Journal: CNS Drugs Date: 2009 Impact factor: 5.749

7. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study.

Authors: Christian Elger; Peter Halász; Joana Maia; Luis Almeida; Patrício Soares-da-Silva
Journal: Epilepsia Date: 2009-02-21 Impact factor: 5.864

8. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial.

Authors: Anthony G Marson; Asya M Al-Kharusi; Muna Alwaidh; Richard Appleton; Gus A Baker; David W Chadwick; Celia Cramp; Oliver C Cockerell; Paul N Cooper; Julie Doughty; Barbara Eaton; Carrol Gamble; Peter J Goulding; Stephen J L Howell; Adrian Hughes; Margaret Jackson; Ann Jacoby; Mark Kellett; Geoffrey R Lawson; John Paul Leach; Paola Nicolaides; Richard Roberts; Phil Shackley; Jing Shen; David F Smith; Philip E M Smith; Catrin Tudur Smith; Alessandra Vanoli; Paula R Williamson
Journal: Lancet Date: 2007-03-24 Impact factor: 79.321

8 in total

5 in total

Eslicarbazepine acetate: a well-kept secret?

Review 1. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes.

2. Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives.

3. Eslicarbazepine acetate: a double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures.

4. Pharmacokinetics of eslicarbazepine acetate in patients with moderate hepatic impairment.

5. Oxcarbazepine and adverse events: impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy.

Review 6. Eslicarbazepine acetate.

7. Efficacy and safety of eslicarbazepine acetate as adjunctive treatment in adults with refractory partial-onset seizures: a randomized, double-blind, placebo-controlled, parallel-group phase III study.

8. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial.

1. [Abrupt switch from extended-release oxcarbazepine to eslicarbazepine acetate].

Review 2. The expanding role of prodrugs in contemporary drug design and development.

3. Update on treatment of partial onset epilepsy: role of eslicarbazepine.

Review 4. The Prodrug Approach: A Successful Tool for Improving Drug Solubility.

5. A review of eslicarbazepine acetate for the adjunctive treatment of partial-onset epilepsy.