Literature DB >> 20119727

Comparison of low dose with standard dose abdominal/pelvic multidetector CT in patients with stage 1 testicular cancer under surveillance.

Martin E O'Malley1, Peter Chung, Masoom Haider, Hyun-Jung Jang, Kartik Jhaveri, Korosh Khalili, Tony Panzarella, Padraig Warde.   

Abstract

PURPOSE: To compare the image quality and acceptability of a low dose with those of standard dose abdominal/pelvic multidetector CT in patients with stage 1 testicular cancer managed by surveillance.
METHODS: One hundred patients (median age 31 years; range 19-83 years), 79 with seminoma and 21 with non-seminoma, underwent abdominal/pelvic imaging with low and standard dose protocols on 64-slice multidetector CT. Three reviewers independently evaluated images for noise and diagnostic quality on a 5-point scale and for diagnostic acceptability.
RESULTS: On average, each reader scored noise and diagnostic quality of standard dose images significantly better than corresponding low dose images (p < 0.0001). One reader found all CT examinations acceptable; two readers each found 1/100 (1%) low dose examinations unacceptable. Median and mean dose-length product for low and standard dose protocols were 416.0 and 452.2 (range 122.9-913.4) and 931.9 and 999.8 (range 283.8-1,987.7) mGy cm, respectively.
CONCLUSIONS: The low dose protocol provided diagnostically acceptable images for at least 99% of patients and achieved mean dose reduction of 55% compared with the standard dose protocol.

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Year:  2010        PMID: 20119727     DOI: 10.1007/s00330-009-1710-1

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


  18 in total

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Authors:  R A Huddart; J K Joffe
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Review 2.  Computed tomography--an increasing source of radiation exposure.

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3.  National survey of doses from CT in the UK: 2003.

Authors:  P C Shrimpton; M C Hillier; M A Lewis; M Dunn
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4.  Comparison of surveillance and retroperitoneal lymph node dissection in Stage I nonseminomatous germ cell tumors.

Authors:  J R Spermon; T A Roeleveld; H G van der Poel; C A Hulsbergen-van de Kaa; W W Ten Bokkel Huinink; M van de Vijver; J A Witjes; S Horenblas
Journal:  Urology       Date:  2002-06       Impact factor: 2.649

5.  Suspected acute colon diverticulitis: imaging with low-dose unenhanced multi-detector row CT.

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6.  Radiation doses from small-bowel follow-through and abdominopelvic MDCT in Crohn's disease.

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7.  Prospective assessment of MRI for imaging retroperitoneal metastases from testicular germ cell tumours.

Authors:  S A Sohaib; D M Koh; Y Barbachano; J Parikh; J E S Husband; D P Dearnaley; A Horwich; R Huddart
Journal:  Clin Radiol       Date:  2008-12-24       Impact factor: 2.350

8.  Acute appendicitis: comparison of low-dose and standard-dose unenhanced multi-detector row CT.

Authors:  Caroline Keyzer; Denis Tack; Viviane de Maertelaer; Pascale Bohy; Pierre Alain Gevenois; Daniel Van Gansbeke
Journal:  Radiology       Date:  2004-05-20       Impact factor: 11.105

Review 9.  European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I.

Authors:  Susanne Krege; Jörg Beyer; Rainer Souchon; Peter Albers; Walter Albrecht; Ferran Algaba; Michael Bamberg; István Bodrogi; Carsten Bokemeyer; Eva Cavallin-Ståhl; Johannes Classen; Christoph Clemm; Gabriella Cohn-Cedermark; Stéphane Culine; Gedske Daugaard; Pieter H M De Mulder; Maria De Santis; Maike de Wit; Ronald de Wit; Hans Günter Derigs; Klaus-Peter Dieckmann; Annette Dieing; Jean-Pierre Droz; Martin Fenner; Karim Fizazi; Aude Flechon; Sophie D Fosså; Xavier Garcia del Muro; Thomas Gauler; Lajos Geczi; Arthur Gerl; Jose Ramon Germa-Lluch; Silke Gillessen; Jörg T Hartmann; Michael Hartmann; Axel Heidenreich; Wolfgang Hoeltl; Alan Horwich; Robert Huddart; Michael Jewett; Johnathan Joffe; William G Jones; László Kisbenedek; Olbjørn Klepp; Sabine Kliesch; Kai Uwe Koehrmann; Christian Kollmannsberger; Markus Kuczyk; Pilar Laguna; Oscar Leiva Galvis; Volker Loy; Malcolm D Mason; Graham M Mead; Rolf Mueller; Craig Nichols; Nicola Nicolai; Tim Oliver; Dalibor Ondrus; Gosse O N Oosterhof; Luis Paz Ares; Giorgio Pizzocaro; Jörg Pont; Tobias Pottek; Tom Powles; Oliver Rick; Giovanni Rosti; Roberto Salvioni; Jutta Scheiderbauer; Hans-Ulrich Schmelz; Heinz Schmidberger; Hans-Joachim Schmoll; Mark Schrader; Felix Sedlmayer; Niels E Skakkebaek; Aslam Sohaib; Sergei Tjulandin; Padraig Warde; Stefan Weinknecht; Lothar Weissbach; Christian Wittekind; Eva Winter; Lori Wood; Hans von der Maase
Journal:  Eur Urol       Date:  2007-12-26       Impact factor: 20.096

10.  Helical CT for nephrolithiasis and ureterolithiasis: comparison of conventional and reduced radiation-dose techniques.

Authors:  Joan P Heneghan; Keith A McGuire; Richard A Leder; David M DeLong; Terry Yoshizumi; Rendon C Nelson
Journal:  Radiology       Date:  2003-10-02       Impact factor: 11.105

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  8 in total

1.  Radionuclide bone scan SPECT-CT: lowering the dose of CT significantly reduces radiation dose without impacting CT image quality.

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Journal:  Am J Nucl Med Mol Imaging       Date:  2017-04-15

2.  Safety of Minimizing Intensity of Follow-up on Active Surveillance for Clinical Stage I Testicular Germ Cell Tumors.

Authors:  Peter J Gariscsak; Lynn Anson-Cartwright; Eshetu G Atenafu; Di Maria Jiang; Peter Chung; Philippe Bedard; Padraig Warde; Martin O'Malley; Joan Sweet; Rachel M Glicksman; Robert J Hamilton
Journal:  Eur Urol Open Sci       Date:  2022-04-27

3.  Patients with testicular cancer undergoing CT surveillance demonstrate a pitfall of radiation-induced cancer risk estimates: the timing paradox.

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Journal:  Radiology       Date:  2012-12-18       Impact factor: 11.105

Review 4.  Clinical dilemmas in local and regional testis cancer.

Authors:  Gregory J Nason; Ricardo A Rendon; Lori Wood; Robert A Huddart; Peter Albers; Lawrence H Einhorn; Craig R Nichols; Christian Kollmannsberger; Lynn Anson-Cartwright; Padraig Warde; Michael A S Jewett; Peter Chung; Philippe L Bedard; Aaron R Hansen; Robert J Hamilton
Journal:  Can Urol Assoc J       Date:  2021-01       Impact factor: 1.862

Review 5.  Recommendations for followup of stage I and II seminoma: The Princess Margaret Cancer Centre approach.

Authors:  Hester Lieng; Padraig Warde; Philippe Bedard; Robert J Hamilton; Aaron R Hansen; Michael A S Jewett; Martin O'malley; Joan Sweet; Peter Chung
Journal:  Can Urol Assoc J       Date:  2017-12-01       Impact factor: 1.862

Review 6.  Contemporary management of stage I and II seminoma.

Authors:  Peter Chung; Padraig Warde
Journal:  Curr Urol Rep       Date:  2013-10       Impact factor: 3.092

Review 7.  Dissecting the Evolving Risk of Relapse over Time in Surveillance for Testicular Cancer.

Authors:  Madhur Nayan; Robert J Hamilton
Journal:  Adv Urol       Date:  2018-02-19

8.  Feasibility of low-dose CT with model-based iterative image reconstruction in follow-up of patients with testicular cancer.

Authors:  Kevin P Murphy; Lee Crush; Siobhan B O'Neill; James Foody; Micheál Breen; Adrian Brady; Paul J Kelly; Derek G Power; Paul Sweeney; Jackie Bye; Owen J O'Connor; Michael M Maher; Kevin N O'Regan
Journal:  Eur J Radiol Open       Date:  2016-02-16
  8 in total

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