Literature DB >> 2011494

Structural and transcriptional analysis of a human subtelomeric repeat.

J F Cheng1, C L Smith, C R Cantor.   

Abstract

A human subtelomeric repeat (designated as the HST repeat) has been isolated and characterized from a yeast artificial chromosome containing one human telomere. This repeat is located immediately adjacent to the telomeric T2AG3 repeats at the extreme termini of the human chromosomes. The DNA sequence of 3.6 kb of the HST repeat has been determined. The HST repeat spans over 3.6 kb in length, and contains one evolutionarily conserved CpG-rich region. The copy number of the HST repeat varies among telomeres. Genomic hybridization experiments suggest that the HST repeat consists of two distinct segments, and the distal portions of the HST repeat are also distributed elsewhere in the genome. In HeLa cells, the HST repeat sequence appears to be transcribed into a 6 kb polyadenylated RNA and a variety of non-polyadenylated RNA species.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 2011494      PMCID： PMC333545          DOI： 10.1093/nar/19.1.149

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  38 in total

1.  Isolation of a telomeric DNA sequence from Drosophila melanogaster.

Authors:  G M Rubin
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1978

2.  RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination.

Authors:  H Lehrach; D Diamond; J M Wozney; H Boedtker
Journal:  Biochemistry       Date:  1977-10-18       Impact factor: 3.162

3.  A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids.

Authors:  C A Kozak; J B Lawrence; F H Ruddle
Journal:  Exp Cell Res       Date:  1977-03-01       Impact factor: 3.905

4.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

Review 5.  Molecular basis for trypanosome antigenic variation.

Authors:  P Borst; G A Cross
Journal:  Cell       Date:  1982-06       Impact factor: 41.582

6.  DNA rearrangements involving the genes for variant antigens in Trypanosoma brucei.

Authors:  P Borst; A C Frasch; A Bernards; L H Van der Ploeg; J H Hoeijmakers; A C Arnberg; G A Cross
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1981

7.  The Huntington disease locus is most likely within 325 kilobases of the chromosome 4p telomere.

Authors:  N A Doggett; J F Cheng; C L Smith; C R Cantor
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205

8.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

9.  Rat insulin genes: construction of plasmids containing the coding sequences.

Authors:  A Ullrich; J Shine; J Chirgwin; R Pictet; E Tischer; W J Rutter; H M Goodman
Journal:  Science       Date:  1977-06-17       Impact factor: 47.728

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
View more
  7 in total

1.  Origin of human chromosome 2: an ancestral telomere-telomere fusion.

Authors:  J W IJdo; A Baldini; D C Ward; S T Reeders; R A Wells
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

2.  Isolation and characterization of a mouse subtelomeric sequence.

Authors:  D Broccoli; O J Miller; D A Miller
Journal:  Chromosoma       Date:  1992-04       Impact factor: 4.316

3.  Characterization of terminal deletions at 7q32 and 22q13.3 healed by De novo telomere addition.

Authors:  H Varley; S Di; S W Scherer; N J Royle
Journal:  Am J Hum Genet       Date:  2000-08-01       Impact factor: 11.025

4.  Characterization of Arabidopsis thaliana telomeres isolated in yeast.

Authors:  E J Richards; S Chao; A Vongs; J Yang
Journal:  Nucleic Acids Res       Date:  1992-08-11       Impact factor: 16.971

5.  ST-1, a 39-kilodalton protein in Trypanosoma brucei, exhibits a dual affinity for the duplex form of the 29-base-pair subtelomeric repeat and its C-rich strand.

Authors:  J E Eid; B Sollner-Webb
Journal:  Mol Cell Biol       Date:  1995-01       Impact factor: 4.272

6.  The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics.

Authors:  E J Louis; E S Naumova; A Lee; G Naumov; J E Haber
Journal:  Genetics       Date:  1994-03       Impact factor: 4.562

7.  Non-coding RNA derived from a conservative subtelomeric tandem repeat in chicken and Japanese quail somatic cells.

Authors:  Irina Trofimova; Darya Popova; Elena Vasilevskaya; Alla Krasikova
Journal:  Mol Cytogenet       Date:  2014-12-23       Impact factor: 2.009
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.