Literature DB >> 20109118

A randomized clinical trial of secondary prevention among women hospitalized with coronary heart disease.

Lori Mosca1, Allison H Christian, Heidi Mochari-Greenberger, Paul Kligfield, Sidney C Smith.   

Abstract

BACKGROUND: Secondary prevention improves survival, yet implementation is suboptimal. We tested the impact of a systematic hospital-based educational intervention vs. usual care to improve rates of adherence to secondary prevention guidelines among women hospitalized with coronary heart disease (CHD), according to their ethnic status.
METHODS: Women (n = 304, 52% minorities) hospitalized with CHD were randomly assigned to a systematic secondary prevention educational intervention vs. usual care. Adherence to goals for smoking cessation, weight management, physical activity, blood pressure <140/90 mm Hg, low-density lipoprotein cholesterol (LDL-C) <100 mg/dL (2.59 mmol/L), and use of aspirin/anticoagulants, beta-blockers, and angiotensin-converting enzyme (ACE) inhibitors were assessed at 6 months.
RESULTS: On admission, minority women were less likely than white women to meet the goals for blood pressure (OR = 0.46, 95% CI 0.26-0.80), LDL-C (OR = 0.57, CI 0.33-0.94), and weight management (OR = 0.40, 95% CI 0.20-0.82). There was no difference between the intervention and usual care groups in a summary score of goals met at study completion; however, minority women in the intervention group were 2.4 times more likely (95% CI 1.13-5.03) to reach the blood pressure goal at 6 months compared with minority women in usual care. White women in the intervention group were 2.86 times more likely (95% CI 1.06-7.68) to report use of beta-blockers at 6 months compared with white women in usual care. In a logistic regression model, the interaction term for ethnic status and group assignment was significant for achieving the blood pressure goal (p = 0.009).
CONCLUSIONS: A healthcare systems approach to educate women about secondary prevention and blood pressure control may differentially benefit ethnic minority women compared with white women.

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Mesh:

Year:  2010        PMID: 20109118      PMCID: PMC2864471          DOI: 10.1089/jwh.2009.1481

Source DB:  PubMed          Journal:  J Womens Health (Larchmt)        ISSN: 1540-9996            Impact factor:   2.681


  27 in total

1.  AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: A statement for healthcare professionals from the American Heart Association and the American College of Cardiology.

Authors:  S C Smith; S N Blair; R O Bonow; L M Brass; M D Cerqueira; K Dracup; V Fuster; A Gotto; S M Grundy; N H Miller; A Jacobs; D Jones; R M Krauss; L Mosca; I Ockene; R C Pasternak; T Pearson; M A Pfeffer; R D Starke; K A Taubert
Journal:  Circulation       Date:  2001-09-25       Impact factor: 29.690

2.  A case-management program of medium intensity does not improve cardiovascular risk factor control in coronary artery disease patients: the Heartcare I trial.

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3.  Improved treatment of coronary heart disease by implementation of a Cardiac Hospitalization Atherosclerosis Management Program (CHAMP).

Authors:  G C Fonarow; A Gawlinski; S Moughrabi; J H Tillisch
Journal:  Am J Cardiol       Date:  2001-04-01       Impact factor: 2.778

Review 4.  Evidence-based guidelines for cardiovascular disease prevention in women: 2007 update.

Authors:  Lori Mosca; Carole L Banka; Emelia J Benjamin; Kathy Berra; Cheryl Bushnell; Rowena J Dolor; Theodore G Ganiats; Antoinette S Gomes; Heather L Gornik; Clarissa Gracia; Martha Gulati; Constance K Haan; Debra R Judelson; Nora Keenan; Ellie Kelepouris; Erin D Michos; L Kristin Newby; Suzanne Oparil; Pamela Ouyang; Mehmet C Oz; Diana Petitti; Vivian W Pinn; Rita F Redberg; Rosalyn Scott; Katherine Sherif; Sidney C Smith; George Sopko; Robin H Steinhorn; Neil J Stone; Kathryn A Taubert; Barbara A Todd; Elaine Urbina; Nanette K Wenger
Journal:  Circulation       Date:  2007-02-19       Impact factor: 29.690

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Authors:  Rajendra H Mehta; Cecelia K Montoye; Meg Gallogly; Patricia Baker; Angela Blount; Jessica Faul; Canopy Roychoudhury; Steven Borzak; Susan Fox; Mary Franklin; Marge Freundl; Eva Kline-Rogers; Thomas LaLonde; Michele Orza; Robert Parrish; Martha Satwicz; Mary Jo Smith; Paul Sobotka; Stuart Winston; Arthur A Riba; Kim A Eagle
Journal:  JAMA       Date:  2002-03-13       Impact factor: 56.272

6.  Clinical reality of coronary prevention guidelines: a comparison of EUROASPIRE I and II in nine countries. EUROASPIRE I and II Group. European Action on Secondary Prevention by Intervention to Reduce Events.

Authors: 
Journal:  Lancet       Date:  2001-03-31       Impact factor: 79.321

7.  Brief intervention during hospital admission to help patients to give up smoking after myocardial infarction and bypass surgery: randomised controlled trial.

Authors:  Peter Hajek; Tamara Z Taylor; Peter Mills
Journal:  BMJ       Date:  2002-01-12

8.  Sex bias and underutilization of lipid-lowering therapy in patients with coronary artery disease at academic medical centers in the United States and Canada. Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT) Investigators.

Authors:  M Miller; R Byington; D Hunninghake; B Pitt; C D Furberg
Journal:  Arch Intern Med       Date:  2000-02-14

9.  Trends and disparities in coronary heart disease, stroke, and other cardiovascular diseases in the United States: findings of the national conference on cardiovascular disease prevention.

Authors:  R Cooper; J Cutler; P Desvigne-Nickens; S P Fortmann; L Friedman; R Havlik; G Hogelin; J Marler; P McGovern; G Morosco; L Mosca; T Pearson; J Stamler; D Stryer; T Thom
Journal:  Circulation       Date:  2000-12-19       Impact factor: 29.690

10.  Breath carbon monoxide as an indication of smoking habit.

Authors:  E T Middleton; A H Morice
Journal:  Chest       Date:  2000-03       Impact factor: 9.410

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Journal:  Cochrane Database Syst Rev       Date:  2012-05-16

2.  When it comes to lifestyle recommendations, more is sometimes less: a meta-analysis of theoretical assumptions underlying the effectiveness of interventions promoting multiple behavior domain change.

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Journal:  Psychol Bull       Date:  2014-12-22       Impact factor: 17.737

3.  The effects of a cardiac rehabilitation program tailored for women on global quality of life: a randomized clinical trial.

Authors:  Theresa M Beckie; Jason W Beckstead
Journal:  J Womens Health (Larchmt)       Date:  2010-09-16       Impact factor: 2.681

  3 in total

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