Literature DB >> 20107659

Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes.

Adrian Fegan1, Pravin S Shirude, Liming Ying, Shankar Balasubramanian.   

Abstract

FRET analysis has been used to examine the folded conformations and differing kinetic stabilities of two DNA G-quadruplexes (c-kit 1 and c-kit 2) derived from sequences found in the promoter of the c-kit proto-oncogene.

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Year:  2009        PMID： 20107659      PMCID： PMC3044463          DOI： 10.1039/b920680a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

1.  Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer.

Authors:  Liming Ying; Jeremy J Green; Haitao Li; David Klenerman; Shankar Balasubramanian
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-25       Impact factor: 11.205

2.  Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.

Authors:  Adam Siddiqui-Jain; Cory L Grand; David J Bearss; Laurence H Hurley
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-23       Impact factor: 11.205

3.  Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter.

Authors:  Thomas S Dexheimer; Daekyu Sun; Laurence H Hurley
Journal:  J Am Chem Soc       Date:  2006-04-26       Impact factor: 15.419

4.  Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein.

Authors:  M K Raghuraman; T R Cech
Journal:  Nucleic Acids Res       Date:  1990-08-11       Impact factor: 16.971

5.  A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics.

Authors:  Shang-Te Danny Hsu; Peter Varnai; Anthony Bugaut; Anthony P Reszka; Stephen Neidle; Shankar Balasubramanian
Journal:  J Am Chem Soc       Date:  2009-09-23       Impact factor: 15.419

6.  Putative DNA quadruplex formation within the human c-kit oncogene.

Authors:  Sarah Rankin; Anthony P Reszka; Julian Huppert; Mire Zloh; Gary N Parkinson; Alan K Todd; Sylvain Ladame; Shankar Balasubramanian; Stephen Neidle
Journal:  J Am Chem Soc       Date:  2005-08-03       Impact factor: 15.419

7.  Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

Authors:  Y Yarden; W J Kuang; T Yang-Feng; L Coussens; S Munemitsu; T J Dull; E Chen; J Schlessinger; U Francke; A Ullrich
Journal:  EMBO J       Date:  1987-11       Impact factor: 11.598

8.  Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.

Authors:  Daekyu Sun; Kexiao Guo; Jadrian J Rusche; Laurence H Hurley
Journal:  Nucleic Acids Res       Date:  2005-10-20       Impact factor: 16.971

9.  Highly prevalent putative quadruplex sequence motifs in human DNA.

Authors:  Alan K Todd; Matthew Johnston; Stephen Neidle
Journal:  Nucleic Acids Res       Date:  2005-05-24       Impact factor: 16.971

10.  Prevalence of quadruplexes in the human genome.

Authors:  Julian L Huppert; Shankar Balasubramanian
Journal:  Nucleic Acids Res       Date:  2005-05-24       Impact factor: 16.971
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  2 in total

1.  Double-stranded flanking ends affect the folding kinetics and conformational equilibrium of G-quadruplexes forming sequences within the promoter of KIT oncogene.

Authors:  Guglielmo Vesco; Marco Lamperti; Domenico Salerno; Claudia Adriana Marrano; Valeria Cassina; Riccardo Rigo; Enrico Buglione; Maria Bondani; Giulia Nicoletto; Francesco Mantegazza; Claudia Sissi; Luca Nardo
Journal:  Nucleic Acids Res       Date:  2021-09-27       Impact factor: 16.971

2.  Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.

Authors:  Wenhua Zhou; Kogularamanan Suntharalingam; Nigel J Brand; Paul J R Barton; Ramon Vilar; Liming Ying
Journal:  PLoS One       Date:  2013-01-09       Impact factor: 3.240
  2 in total

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