Literature DB >> 20106398

Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database.

Subroto Paul1, Nasser K Altorki, Shubin Sheng, Paul C Lee, David H Harpole, Mark W Onaitis, Brendon M Stiles, Jeffrey L Port, Thomas A D'Amico.   

Abstract

BACKGROUND: Several single-institution series have demonstrated that compared with open thoracotomy, video-assisted thoracoscopic lobectomy may be associated with fewer postoperative complications. In the absence of randomized trials, we queried the Society of Thoracic Surgeons database to compare postoperative mortality and morbidity following open and video-assisted thoracoscopic lobectomy. A propensity-matched analysis using a large national database may enable a more comprehensive comparison of postoperative outcomes.
METHODS: All patients having lobectomy as the primary procedure via thoracoscopy or thoracotomy were identified in the Society of Thoracic Surgeons database from 2002 to 2007. After exclusions, 6323 patients were identified: 5042 having thoracotomy, 1281 having thoracoscopy. A propensity analysis was performed, incorporating preoperative variables, and the incidence of postoperative complications was compared.
RESULTS: Matching based on propensity scores produced 1281 patients in each group for analysis of postoperative outcomes. After video-assisted thoracoscopic lobectomy, 945 patients (73.8%) had no complications, compared with 847 patients (65.3%) who had lobectomy via thoracotomy (P < .0001). Compared with open lobectomy, video-assisted thoracoscopic lobectomy was associated with a lower incidence of arrhythmias [n = 93 (7.3%) vs 147 (11.5%); P = .0004], reintubation [n = 18 (1.4%) vs 40 (3.1%); P = .0046], and blood transfusion [n = 31 (2.4%) vs n = 60 (4.7%); P = .0028], as well as a shorter length of stay (4.0 vs 6.0 days; P < .0001) and chest tube duration (3.0 vs 4.0 days; P < .0001). There was no difference in operative mortality between the 2 groups.
CONCLUSIONS: Video-assisted thoracoscopic lobectomy is associated with a lower incidence of complications compared with lobectomy via thoracotomy. For appropriate candidates, video-assisted thoracoscopic lobectomy may be the preferred strategy for appropriately selected patients with lung cancer. 2010 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2010        PMID: 20106398     DOI: 10.1016/j.jtcvs.2009.08.026

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  213 in total

1.  Video-assisted thoracoscopic surgery (VATS) anatomic lung resection.

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2.  Self-perceived video-assisted thoracic surgery lobectomy proficiency by recent graduates of North American thoracic residencies.

Authors:  Daniel J Boffa; Sidharta Gangadharan; Michael Kent; Faraz Kerendi; Mark Onaitis; Edward Verrier; Eric Roselli
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Review 3.  Video-assisted thoracic surgery for lung cancer.

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Journal:  Gen Thorac Cardiovasc Surg       Date:  2012-03-28

4.  Improving lung cancer outcomes by improving the quality of surgical care.

Authors:  Raymond U Osarogiagbon; Thomas A D'Amico
Journal:  Transl Lung Cancer Res       Date:  2015-08

5.  Editorial comment on: "Major morbidity after video-assisted thoracic surgery lung resections: a comparison between the European Society of Thoracic Surgeons definition and the Thoracic Morbidity and Mortality system" by Sandri A, et al.

Authors:  Pierre-Emmanuel Falcoz
Journal:  J Thorac Dis       Date:  2015-09       Impact factor: 2.895

6.  Troubleshooting thoracoscopic anterior mediastinal surgery: lessons learned from thoracoscopic lobectomy.

Authors:  Sameer A Hirji; Scott S Balderson; Mark F Berry; Thomas A D'Amico
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7.  Major morbidity after video-assisted thoracic surgery lung resections: a comparison between the European Society of Thoracic Surgeons definition and the Thoracic Morbidity and Mortality system.

Authors:  Alberto Sandri; Kostas Papagiannopoulos; Richard Milton; Emmanuel Kefaloyannis; Nilanjan Chaudhuri; Emily Poyser; Nicholas Spencer; Alessandro Brunelli
Journal:  J Thorac Dis       Date:  2015-07       Impact factor: 2.895

8.  Quality Measures in Clinical Stage I Non-Small Cell Lung Cancer: Improved Performance Is Associated With Improved Survival.

Authors:  Pamela Samson; Traves Crabtree; Stephen Broderick; Daniel Kreisel; A Sasha Krupnick; G Alexander Patterson; Bryan Meyers; Varun Puri
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9.  Indication for VATS sublobar resections in early lung cancer.

Authors:  Antonio E Martin-Ucar; Maria Delgado Roel
Journal:  J Thorac Dis       Date:  2013-08       Impact factor: 2.895

Review 10.  Contraindications of video-assisted thoracoscopic surgical lobectomy and determinants of conversion to open.

Authors:  Jennifer M Hanna; Mark F Berry; Thomas A D'Amico
Journal:  J Thorac Dis       Date:  2013-08       Impact factor: 2.895

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