BACKGROUND: Previous studies have suggested that egg consumption may increase the risk of colorectal cancer and some other cancers. However, the evidence is still limited. To further explore the association between egg intake and cancer risk we conducted a case-control study of 11 cancer sites in Uruguay between 1996 and 2004, including 3,539 cancer cases and 2,032 hospital controls. RESULTS: In the multivariable model with adjustment for age, sex (when applicable), residence, education, income, interviewer, smoking, alcohol intake, intake of fruits and vegetables, grains, dairy products, fatty foods, meat, energy intake and BMI, there was a significant increase in the odds of cancers of the oral cavity and pharynx (OR= 2.02, 95% CI: 1.19-3.44), upper aerodigestive tract (OR= 1.67, 95% CI: 1.17-2.37), colorectum (OR= 1.64, 95% CI: 1.02-2.63), lung (OR= 1.59, 95% CI: 1.10-2.29), breast (OR= 2.86, 95% CI: 1.66-4.92), prostate (OR= 1.89, 95% CI: 1.15-3.10), bladder (OR= 2.23, 95% CI: 1.30-3.83) and all cancer sites combined (OR= 1.71, 95% CI: 1.35-2.17) with a high vs low egg intake. CONCLUSIONS: We found an association between higher intake of eggs and increased risk of several cancers. Further prospective studies of these associations are warranted.
BACKGROUND: Previous studies have suggested that egg consumption may increase the risk of colorectal cancer and some other cancers. However, the evidence is still limited. To further explore the association between egg intake and cancer risk we conducted a case-control study of 11 cancer sites in Uruguay between 1996 and 2004, including 3,539 cancer cases and 2,032 hospital controls. RESULTS: In the multivariable model with adjustment for age, sex (when applicable), residence, education, income, interviewer, smoking, alcohol intake, intake of fruits and vegetables, grains, dairy products, fatty foods, meat, energy intake and BMI, there was a significant increase in the odds of cancers of the oral cavity and pharynx (OR= 2.02, 95% CI: 1.19-3.44), upper aerodigestive tract (OR= 1.67, 95% CI: 1.17-2.37), colorectum (OR= 1.64, 95% CI: 1.02-2.63), lung (OR= 1.59, 95% CI: 1.10-2.29), breast (OR= 2.86, 95% CI: 1.66-4.92), prostate (OR= 1.89, 95% CI: 1.15-3.10), bladder (OR= 2.23, 95% CI: 1.30-3.83) and all cancer sites combined (OR= 1.71, 95% CI: 1.35-2.17) with a high vs low egg intake. CONCLUSIONS: We found an association between higher intake of eggs and increased risk of several cancers. Further prospective studies of these associations are warranted.
Authors: Shu-Chun Chuang; Mazda Jenab; Julia E Heck; Cristina Bosetti; Renato Talamini; Keitaro Matsuo; Xavier Castellsague; Silvia Franceschi; Rolando Herrero; Deborah M Winn; Carlo La Vecchia; Hal Morgenstern; Zuo-Feng Zhang; Fabio Levi; Luigino Dal Maso; Karl Kelsey; Michael D McClean; Thomas Vaughan; Philip Lazarus; Joshua Muscat; Heribert Ramroth; Chu Chen; Stephen M Schwartz; Jose Eluf-Neto; Richard B Hayes; Mark Purdue; Stefania Boccia; Gabriella Cadoni; David Zaridze; Sergio Koifman; Maria Paula Curado; Wolfgang Ahrens; Simone Benhamou; Elena Matos; Pagona Lagiou; Neonilla Szeszenia-Dabrowska; Andrew F Olshan; Leticia Fernandez; Ana Menezes; Antonio Agudo; Alexander W Daudt; Franco Merletti; Gary J Macfarlane; Kristina Kjaerheim; Dana Mates; Ivana Holcatova; Stimson Schantz; Guo-Pei Yu; Lorenzo Simonato; Hermann Brenner; Heiko Mueller; David I Conway; Peter Thomson; Eleonora Fabianova; Ariana Znaor; Peter Rudnai; Claire M Healy; Gilles Ferro; Paul Brennan; Paolo Boffetta; Mia Hashibe Journal: Cancer Causes Control Date: 2011-10-29 Impact factor: 2.506
Authors: F Bravi; C Bosetti; M Filomeno; F Levi; W Garavello; S Galimberti; E Negri; C La Vecchia Journal: Br J Cancer Date: 2013-10-22 Impact factor: 7.640