BACKGROUND:Intrauterine contraception can provide adolescents with effective, long-term contraception as well as with other health benefits. In adult populations, intrauterine contraception rates highly in patient satisfaction and safety. It is rarely prescribed to adolescents because of limited data. STUDY DESIGN: Multicenter, randomized, controlled, participant-blinded pilot study of 14-18-year-old females assigned to the Copper T 380A intrauterine device or the Levonorgestrel Intrauterine System. Participants were followed up for 6 months following insertion. RESULTS:We enrolled 23 participants; 12 received theLevonorgestrel Intrauterine System, and 11 received the Copper T 380A. At 6 months, the continuation rates were 75% for the Levonorgestrel Intrauterine System users and 45% for the Copper T 380A users (p=.15). Two Copper T 380A users experienced partial expulsion. Heavy bleeding and pelvic pain were the most commonly reported side effects. Participants rated both methods favorably. CONCLUSIONS: This study shows that at 6 months, though not statistically significant, adolescent continuation rates trended towards being greater with the Levonorgestrel Intrauterine System compared to the Copper T 380A. These pilot data will be helpful in the design of a larger trial of intrauterine contraception use among adolescents.
RCT Entities:
BACKGROUND: Intrauterine contraception can provide adolescents with effective, long-term contraception as well as with other health benefits. In adult populations, intrauterine contraception rates highly in patient satisfaction and safety. It is rarely prescribed to adolescents because of limited data. STUDY DESIGN: Multicenter, randomized, controlled, participant-blinded pilot study of 14-18-year-old females assigned to the CopperT 380A intrauterine device or the Levonorgestrel Intrauterine System. Participants were followed up for 6 months following insertion. RESULTS: We enrolled 23 participants; 12 received the Levonorgestrel Intrauterine System, and 11 received the CopperT 380A. At 6 months, the continuation rates were 75% for the Levonorgestrel Intrauterine System users and 45% for the CopperT 380A users (p=.15). Two CopperT 380A users experienced partial expulsion. Heavy bleeding and pelvic pain were the most commonly reported side effects. Participants rated both methods favorably. CONCLUSIONS: This study shows that at 6 months, though not statistically significant, adolescent continuation rates trended towards being greater with the Levonorgestrel Intrauterine System compared to the CopperT 380A. These pilot data will be helpful in the design of a larger trial of intrauterine contraception use among adolescents.
Authors: Sharon L Achilles; Beatrice A Chen; Jessica K Lee; Aileen M Gariepy; Mitchell D Creinin Journal: Contraception Date: 2015-08-18 Impact factor: 3.375
Authors: Natalia I Douglas; Tatiana U Pavlova; Tatiana E Burtseva; Yana G Rad; Palmira G Petrova; Jon Ø Odland Journal: Int J Circumpolar Health Date: 2014-10-30 Impact factor: 1.228