Andrew E Firth1, John F Atkins. 1. BioSciences Institute, University College Cork, Cork, Ireland. A.Firth@ucc.ie
Abstract
BACKGROUND: Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software. Recently we have been using a number of complementary approaches to systematically identify previously undetected overlapping genes in RNA virus genomes. In this article we gather together a number of promising candidate new overlapping genes that may be of interest to the community. RESULTS: Overlapping gene predictions are presented for the astroviruses, seadornaviruses, cytorhabdoviruses and coronaviruses (families Astroviridae, Reoviridae, Rhabdoviridae and Coronaviridae, respectively).
BACKGROUND: Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software. Recently we have been using a number of complementary approaches to systematically identify previously undetected overlapping genes in RNA virus genomes. In this article we gather together a number of promising candidate new overlapping genes that may be of interest to the community. RESULTS: Overlapping gene predictions are presented for the astroviruses, seadornaviruses, cytorhabdoviruses and coronaviruses (families Astroviridae, Reoviridae, Rhabdoviridae and Coronaviridae, respectively).
Authors: Ezequiel Balmori Melian; Edward Hinzman; Tomoko Nagasaki; Andrew E Firth; Norma M Wills; Amanda S Nouwens; Bradley J Blitvich; Jason Leung; Anneke Funk; John F Atkins; Roy Hall; Alexander A Khromykh Journal: J Virol Date: 2009-11-11 Impact factor: 5.103
Authors: Joseph J Carter; Matthew D Daugherty; Xiaojie Qi; Anjali Bheda-Malge; Gregory C Wipf; Kristin Robinson; Ann Roman; Harmit S Malik; Denise A Galloway Journal: Proc Natl Acad Sci U S A Date: 2013-07-11 Impact factor: 11.205