Dustin K Ragan1, James A Bankson. 1. Department of Imaging Physics, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Abstract
PURPOSE: To determine whether Dixon-based fat separation techniques can provide more robust removal of lipid signals from multiple-mouse magnetic resonance imaging (MRI)-acquired images than conventional frequency selective chemical saturation techniques. MATERIALS AND METHODS: A two-point Dixon technique was implemented using a RARE-based pulse sequence and techniques for multivolume fat suppression were evaluated using a 4-element array of volume resonators at 4.7 T. Images were acquired of both phantoms and mice. RESULTS: Fat saturation was achieved on all four channels of the multiple mouse acquisition with the Dixon technique, while failures of fat saturation were found with chemical saturation techniques. CONCLUSION: This proof of concept study found that Dixon fat separation provided more reliable and homogenous fat suppression than chemical saturation in phantoms and in vivo.
PURPOSE: To determine whether Dixon-based fat separation techniques can provide more robust removal of lipid signals from multiple-mouse magnetic resonance imaging (MRI)-acquired images than conventional frequency selective chemical saturation techniques. MATERIALS AND METHODS: A two-point Dixon technique was implemented using a RARE-based pulse sequence and techniques for multivolume fat suppression were evaluated using a 4-element array of volume resonators at 4.7 T. Images were acquired of both phantoms and mice. RESULTS: Fat saturation was achieved on all four channels of the multiple mouse acquisition with the Dixon technique, while failures of fat saturation were found with chemical saturation techniques. CONCLUSION: This proof of concept study found that Dixon fat separation provided more reliable and homogenous fat suppression than chemical saturation in phantoms and in vivo.
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