BACKGROUND: We aimed to determine predictors of morbidity in patients undergoing microvascular free flap reconstruction of the head and neck. METHODS: We prospectively evaluated 796 cases between 1999 and 2007 using univariate and multivariate analysis to determine predictors of morbidity and prolonged hospital stay. RESULTS: Two hundred thirty-nine patients (30%) developed major complications. Age, body mass index (BMI), American Society of Anesthesiology (ASA) score, Kaplan Feinstein comorbidity index (KFI) score, preoperative hemoglobin, and tracheostomy were independent predictors of major complication. Predictors of prolonged hospital stay included age, recent weight loss, alcohol excess, ASA, KFI, preoperative hemoglobin, mucosal surgery, anesthesia duration, and crystalloid replacement volume. CONCLUSION: Several variables are associated with an increased risk of development of major complications following free flap reconstruction of the head and neck. Although many of these variables are irreversible, they aid risk stratification of patients undergoing free flap reconstruction, and assist clinicians in making treatment decisions, consenting, and providing patients with realistic expectations regarding their perioperative course.
BACKGROUND: We aimed to determine predictors of morbidity in patients undergoing microvascular free flap reconstruction of the head and neck. METHODS: We prospectively evaluated 796 cases between 1999 and 2007 using univariate and multivariate analysis to determine predictors of morbidity and prolonged hospital stay. RESULTS: Two hundred thirty-nine patients (30%) developed major complications. Age, body mass index (BMI), American Society of Anesthesiology (ASA) score, Kaplan Feinstein comorbidity index (KFI) score, preoperative hemoglobin, and tracheostomy were independent predictors of major complication. Predictors of prolonged hospital stay included age, recent weight loss, alcohol excess, ASA, KFI, preoperative hemoglobin, mucosal surgery, anesthesia duration, and crystalloid replacement volume. CONCLUSION: Several variables are associated with an increased risk of development of major complications following free flap reconstruction of the head and neck. Although many of these variables are irreversible, they aid risk stratification of patients undergoing free flap reconstruction, and assist clinicians in making treatment decisions, consenting, and providing patients with realistic expectations regarding their perioperative course.
Authors: Mahmoud I Awad; Frank L Palmer; Lei Kou; Changhong Yu; Pablo H Montero; Andrew G Shuman; Ian Ganly; Jatin P Shah; Michael W Kattan; Snehal G Patel Journal: JAMA Otolaryngol Head Neck Surg Date: 2015-11 Impact factor: 6.223
Authors: Carol M Lewis; Thomas A Aloia; Weiming Shi; Ira Martin; Stephen Y Lai; Jesse C Selber; Amy C Hessel; Matthew M Hanasono; Katherine A Hutcheson; Geoffrey L Robb; Randal S Weber Journal: JAMA Otolaryngol Head Neck Surg Date: 2016-04 Impact factor: 6.223
Authors: Joseph Zenga; Jeffrey D Sharon; Paul Santiago; Brian Nussenbaum; Bruce H Haughey; Ida K Fox; Terence M Myckatyn; Jason A Diaz; Michael R Chicoine Journal: J Neurol Surg B Skull Base Date: 2015-05-22
Authors: Bryan J Dooley; Daniella Karassawa Zanoni; Marlena R Mcgill; Mahmoud I Awad; Jatin P Shah; Richard J Wong; Clara Broad; Babak J Mehrara; Ian Ganly; Snehal G Patel Journal: Head Neck Date: 2019-10-08 Impact factor: 3.147
Authors: Gabriel de la Garza; Oleg Militsakh; Aru Panwar; Tabitha L Galloway; Jeffrey B Jorgensen; Levi G Ledgerwood; Katelyn Kaiser; Collin Kitzerow; Yelizaveta Shnayder; Colin A Neumann; Samir S Khariwala; W Chad Spanos; Nitin A Pagedar Journal: Head Neck Date: 2015-08-13 Impact factor: 3.147
Authors: Aladine A Elsamadicy; Owoicho Adogwa; Victoria D Vuong; Amanda Sergesketter; Gireesh Reddy; Joseph Cheng; Carlos A Bagley; Isaac O Karikari Journal: J Spine Surg Date: 2017-09