Literature DB >> 20090966

(-)-Bacillamide C: the convergent approach.

Wei Wang1, Shannon Joyner, Kareem Andrew Sameer Khoury, Alexander Dömling.   

Abstract

The newly discovered natural product bacillamide C and several derivatives were convergently synthesized for the first time and in only three steps. The key transformation constitutes a thiazole Ugi multicomponent reaction. These compounds will serve to elucidate chemical biology and SAR of this potent anti-algae natural product and shows the synthetic pathway to related natural products.

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Year:  2009        PMID: 20090966     DOI: 10.1039/b918214d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  6 in total

Review 1.  Chemistry and biology of multicomponent reactions.

Authors:  Alexander Dömling; Wei Wang; Kan Wang
Journal:  Chem Rev       Date:  2012-03-22       Impact factor: 60.622

2.  1,4-Thienodiazepine-2,5-diones via MCR (II): scaffold hopping by Gewald and Ugi-deprotection-cyclization strategy.

Authors:  Yijun Huang; Alexander Dömling
Journal:  Chem Biol Drug Des       Date:  2010-06-09       Impact factor: 2.817

Review 3.  Thiazole and oxazole alkaloids: isolation and synthesis.

Authors:  Danilo Davyt; Gloria Serra
Journal:  Mar Drugs       Date:  2010-11-05       Impact factor: 5.118

4.  The role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89.

Authors:  Lei Yuwen; Feng-Li Zhang; Qi-Hua Chen; Shuang-Jun Lin; Yi-Lei Zhao; Zhi-Yong Li
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379

Review 5.  Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics.

Authors:  Gijs Koopmanschap; Eelco Ruijter; Romano Va Orru
Journal:  Beilstein J Org Chem       Date:  2014-03-04       Impact factor: 2.883

6.  Algicidal Activity of Bacillamide Alkaloids and Their Analogues against Marine and Freshwater Harmful Algae.

Authors:  Bo Wang; Yuanyuan Tao; Qisheng Liu; Na Liu; Zhong Jin; Xiaohua Xu
Journal:  Mar Drugs       Date:  2017-08-07       Impact factor: 5.118

  6 in total

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