Literature DB >> 20089957

Projected effect of dietary salt reductions on future cardiovascular disease.

Kirsten Bibbins-Domingo1, Glenn M Chertow, Pamela G Coxson, Andrew Moran, James M Lightwood, Mark J Pletcher, Lee Goldman.   

Abstract

BACKGROUND: The U.S. diet is high in salt, with the majority coming from processed foods. Reducing dietary salt is a potentially important target for the improvement of public health.
METHODS: We used the Coronary Heart Disease (CHD) Policy Model to quantify the benefits of potentially achievable, population-wide reductions in dietary salt of up to 3 g per day (1200 mg of sodium per day). We estimated the rates and costs of cardiovascular disease in subgroups defined by age, sex, and race; compared the effects of salt reduction with those of other interventions intended to reduce the risk of cardiovascular disease; and determined the cost-effectiveness of salt reduction as compared with the treatment of hypertension with medications.
RESULTS: Reducing dietary salt by 3 g per day is projected to reduce the annual number of new cases of CHD by 60,000 to 120,000, stroke by 32,000 to 66,000, and myocardial infarction by 54,000 to 99,000 and to reduce the annual number of deaths from any cause by 44,000 to 92,000. All segments of the population would benefit, with blacks benefiting proportionately more, women benefiting particularly from stroke reduction, older adults from reductions in CHD events, and younger adults from lower mortality rates. The cardiovascular benefits of reduced salt intake are on par with the benefits of population-wide reductions in tobacco use, obesity, and cholesterol levels. A regulatory intervention designed to achieve a reduction in salt intake of 3 g per day would save 194,000 to 392,000 quality-adjusted life-years and $10 billion to $24 billion in health care costs annually. Such an intervention would be cost-saving even if only a modest reduction of 1 g per day were achieved gradually between 2010 and 2019 and would be more cost-effective than using medications to lower blood pressure in all persons with hypertension.
CONCLUSIONS: Modest reductions in dietary salt could substantially reduce cardiovascular events and medical costs and should be a public health target. 2010 Massachusetts Medical Society

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Year:  2010        PMID: 20089957      PMCID: PMC3066566          DOI: 10.1056/NEJMoa0907355

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  36 in total

1.  Double-blind randomised trial of modest salt restriction in older people.

Authors:  F P Cappuccio; N D Markandu; C Carney; G A Sagnella; G A MacGregor
Journal:  Lancet       Date:  1997-09-20       Impact factor: 79.321

2.  The urgent need to reduce sodium consumption.

Authors:  Stephen Havas; Barry D Dickinson; Modena Wilson
Journal:  JAMA       Date:  2007-09-26       Impact factor: 56.272

3.  By how much does dietary salt reduction lower blood pressure? III--Analysis of data from trials of salt reduction.

Authors:  M R Law; C D Frost; N J Wald
Journal:  BMJ       Date:  1991-04-06

4.  Relative contributions of dietary sodium sources.

Authors:  R D Mattes; D Donnelly
Journal:  J Am Coll Nutr       Date:  1991-08       Impact factor: 3.169

5.  Incidence and occurrence of total (first-ever and recurrent) stroke.

Authors:  G R Williams; J G Jiang; D B Matchar; G P Samsa
Journal:  Stroke       Date:  1999-12       Impact factor: 7.914

6.  Coronary heart disease attributable to passive smoking: CHD Policy Model.

Authors:  James M Lightwood; Pamela G Coxson; Kirsten Bibbins-Domingo; Lawrence W Williams; Lee Goldman
Journal:  Am J Prev Med       Date:  2009-01       Impact factor: 5.043

Review 7.  Chronic disease prevention: health effects and financial costs of strategies to reduce salt intake and control tobacco use.

Authors:  Perviz Asaria; Dan Chisholm; Colin Mathers; Majid Ezzati; Robert Beaglehole
Journal:  Lancet       Date:  2007-12-11       Impact factor: 79.321

8.  Cost-effectiveness of chlorthalidone, amlodipine, and lisinopril as first-step treatment for patients with hypertension: an analysis of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Authors:  Paul A Heidenreich; Barry R Davis; Jeffrey A Cutler; Curt D Furberg; David R Lairson; Michael G Shlipak; Sara L Pressel; Chuke Nwachuku; Lee Goldman
Journal:  J Gen Intern Med       Date:  2008-01-29       Impact factor: 5.128

9.  Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP).

Authors:  Nancy R Cook; Jeffrey A Cutler; Eva Obarzanek; Julie E Buring; Kathryn M Rexrode; Shiriki K Kumanyika; Lawrence J Appel; Paul K Whelton
Journal:  BMJ       Date:  2007-04-20

10.  Adolescent overweight and future adult coronary heart disease.

Authors:  Kirsten Bibbins-Domingo; Pamela Coxson; Mark J Pletcher; James Lightwood; Lee Goldman
Journal:  N Engl J Med       Date:  2007-12-06       Impact factor: 91.245

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3.  Using stress testing to guide primary prevention of coronary heart disease among intermediate-risk patients: a cost-effectiveness analysis.

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Journal:  Circulation       Date:  2011-12-05       Impact factor: 29.690

4.  Heart disease and stroke statistics--2012 update: a report from the American Heart Association.

Authors:  Véronique L Roger; Alan S Go; Donald M Lloyd-Jones; Emelia J Benjamin; Jarett D Berry; William B Borden; Dawn M Bravata; Shifan Dai; Earl S Ford; Caroline S Fox; Heather J Fullerton; Cathleen Gillespie; Susan M Hailpern; John A Heit; Virginia J Howard; Brett M Kissela; Steven J Kittner; Daniel T Lackland; Judith H Lichtman; Lynda D Lisabeth; Diane M Makuc; Gregory M Marcus; Ariane Marelli; David B Matchar; Claudia S Moy; Dariush Mozaffarian; Michael E Mussolino; Graham Nichol; Nina P Paynter; Elsayed Z Soliman; Paul D Sorlie; Nona Sotoodehnia; Tanya N Turan; Salim S Virani; Nathan D Wong; Daniel Woo; Melanie B Turner
Journal:  Circulation       Date:  2011-12-15       Impact factor: 29.690

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Authors:  Susan M Kansagra; Thomas A Farley
Journal:  Am J Public Health       Date:  2011-10-20       Impact factor: 9.308

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Authors:  Nick Wilson; Tony Blakely; Rachel H Foster; David Hadorn; Theo Vos
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Review 7.  Epidemiology, diagnosis and management of hypertension among patients on chronic dialysis.

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Journal:  Nat Rev Nephrol       Date:  2016-08-30       Impact factor: 28.314

Review 8.  The crosstalk of gut microbiota and chronic kidney disease: role of inflammation, proteinuria, hypertension, and diabetes mellitus.

Authors:  Mehmet Kanbay; Emine M Onal; Baris Afsar; Tuncay Dagel; Aslihan Yerlikaya; Adrian Covic; Nosratola D Vaziri
Journal:  Int Urol Nephrol       Date:  2018-05-04       Impact factor: 2.370

9.  Impact on cardiovascular disease events of the implementation of Argentina's national tobacco control law.

Authors:  Jonatan Konfino; Daniel Ferrante; Raul Mejia; Pamela Coxson; Andrew Moran; Lee Goldman; Eliseo J Pérez-Stable
Journal:  Tob Control       Date:  2012-10-23       Impact factor: 7.552

10.  Sodium intake in a cross-sectional, representative sample of New York City adults.

Authors:  Sonia Y Angell; Stella Yi; Donna Eisenhower; Bonnie D Kerker; Christine J Curtis; Katherine Bartley; Lynn D Silver; Thomas A Farley
Journal:  Am J Public Health       Date:  2014-01-16       Impact factor: 9.308

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