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Literature DB >> 20086140

In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp.

Mohammad J Najafzadeh¹, Hamid Badali, Maria Teresa Illnait-Zaragozi, G Sybren De Hoog, Jacques F Meis.

Abstract

The in vitro activities of eight antifungal drugs against clinical isolates of Fonsecaea pedrosoi (n = 21), Fonsecaea monophora (n = 25), and Fonsecaea nubica (n = 9) were tested. The resulting MIC(90)s for all strains (n = 55) were as follows, in increasing order: posaconazole, 0.063 microg/ml; itraconazole, 0.125 microg/ml; isavuconazole, 0.25 microg/ml; voriconazole, 0.5 microg/ml; amphotericin B, 2 microg/ml; caspofungin, 2 microg/ml; anidulafungin, 2 microg/ml; and fluconazole, 32 microg/ml.

Entities: Species

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Year: 2010 PMID： 20086140 PMCID： PMC2849378 DOI： 10.1128/AAC.01655-09

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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