Literature DB >> 20069388

Transcriptional target-based expression cloning of immunoregulatory molecules.

Rebecca L Lamason1, Stefanie M Lew, Joel L Pomerantz.   

Abstract

Immunologic research has benefited tremendously from expression-cloning strategies designed to isolate genes responsible for a wide variety of immunomodulatory activities, including cytokines, receptors, signaling proteins, and transcription factors. Here, we discuss the use of expression-cloning strategies that have been modified to detect cDNAs that influence gene expression as assayed by a transcriptional reporter. We summarize our experience with these screens, review important parameters, and discuss potential modifications.

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Year:  2010        PMID： 20069388      PMCID： PMC2892239          DOI： 10.1007/s12026-009-8148-z

Source DB:  PubMed          Journal:  Immunol Res        ISSN： 0257-277X            Impact factor:   2.829


  13 in total

1.  Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

Authors:  Janet D Siliciano; Joleen Kajdas; Diana Finzi; Thomas C Quinn; Karen Chadwick; Joseph B Margolick; Colin Kovacs; Stephen J Gange; Robert F Siliciano
Journal:  Nat Med       Date:  2003-05-18       Impact factor: 53.440

2.  CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex.

Authors:  Joel L Pomerantz; Elissa M Denny; David Baltimore
Journal:  EMBO J       Date:  2002-10-01       Impact factor: 11.598

3.  Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.

Authors:  Hung-Chih Yang; Lin Shen; Robert F Siliciano; Joel L Pomerantz
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-31       Impact factor: 11.205

4.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

Authors:  F J Palella; K M Delaney; A C Moorman; M O Loveless; J Fuhrer; G A Satten; D J Aschman; S D Holmberg
Journal:  N Engl J Med       Date:  1998-03-26       Impact factor: 91.245

Review 5.  NF-kappaB and the immune response.

Authors:  M S Hayden; A P West; S Ghosh
Journal:  Oncogene       Date:  2006-10-30       Impact factor: 9.867

6.  Requirement for CARMA1 in antigen receptor-induced NF-kappa B activation and lymphocyte proliferation.

Authors:  Takeshi Egawa; Björn Albrecht; Benoît Favier; Mary-Jean Sunshine; Kanchan Mirchandani; William O'Brien; Margot Thome; Dan R Littman
Journal:  Curr Biol       Date:  2003-07-15       Impact factor: 10.834

7.  The MAGUK family protein CARD11 is essential for lymphocyte activation.

Authors:  Hiromitsu Hara; Teiji Wada; Chris Bakal; Ivona Kozieradzki; Shinobu Suzuki; Nobutaka Suzuki; Mai Nghiem; Emily K Griffiths; Connie Krawczyk; Birgit Bauer; Fulvio D'Acquisto; Sankar Ghosh; Wen Chen Yeh; Gottfried Baier; Robert Rottapel; Josef M Penninger
Journal:  Immunity       Date:  2003-06       Impact factor: 31.745

8.  Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

Authors:  Jesse E Jun; Lauren E Wilson; Carola G Vinuesa; Sylvie Lesage; Mathieu Blery; Lisa A Miosge; Matthew C Cook; Edyta M Kucharska; Hiromitsu Hara; Josef M Penninger; Heather Domashenz; Nancy A Hong; Richard J Glynne; Keats A Nelms; Christopher C Goodnow
Journal:  Immunity       Date:  2003-06       Impact factor: 31.745

9.  A requirement for CARMA1 in TCR-induced NF-kappa B activation.

Authors:  Donghai Wang; Yun You; Sara M Case; Linda M McAllister-Lucas; Lin Wang; Peter S DiStefano; Gabriel Nuñez; John Bertin; Xin Lin
Journal:  Nat Immunol       Date:  2002-08-05       Impact factor: 25.606

10.  CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation.

Authors:  Olivier Gaide; Benoît Favier; Daniel F Legler; David Bonnet; Brian Brissoni; Salvatore Valitutti; Claude Bron; Jürg Tschopp; Margot Thome
Journal:  Nat Immunol       Date:  2002-08-05       Impact factor: 25.606
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  2 in total

1.  A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival.

Authors:  Waipan Chan; Thomas B Schaffer; Joel L Pomerantz
Journal:  Mol Cell Biol       Date:  2012-11-12       Impact factor: 4.272

2.  A protease-independent function for SPPL3 in NFAT activation.

Authors:  Stefanie L Makowski; Zhaoquan Wang; Joel L Pomerantz
Journal:  Mol Cell Biol       Date:  2014-11-10       Impact factor: 4.272
  2 in total

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