Literature DB >> 20059752

The number of lung transplants can be safely doubled using extended criteria donors; a single-center review.

Caroline Meers1, Dirk Van Raemdonck, Geert M Verleden, Willy Coosemans, Herbert Decaluwe, Paul De Leyn, Philippe Nafteux, Toni Lerut.   

Abstract

Relaxing the standard lung donor criteria may significantly increase the reported 15% organ yield but post-transplant recipient outcome should be carefully monitored. Charts from all consecutive deceased organ donors within our hospital network were reviewed over a 2-year period. Reasons for lung refusals and number of lungs transplanted were analysed. Hospital outcome including early recipient survival was compared between standard- and extended criteria donors. Out of 283 referrals, 164 (58%) qualified as donor of any organ. The majority (65.9%) of these effective donors were declined for lung donation because of chest X-ray abnormalities (20%), age >70 years (13%), poor oxygenation (10%), or aspiration (9%). Out of 56 (34.1%) accepted lung donors, 50 transplants were performed at our center, 23 from standard criteria donors versus 27 from extended criteria donors. There were no significant differences in hospital outcome and in early survival between lung recipients from both donor groups. Lung acceptance rate (34.1%) in our donor network is 10-20% higher than reported figures. The number of lung transplants in our center doubled by accepting extended criteria donors. This policy did not negatively influence our results after lung transplantation.

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Year:  2010        PMID: 20059752     DOI: 10.1111/j.1432-2277.2009.01033.x

Source DB:  PubMed          Journal:  Transpl Int        ISSN: 0934-0874            Impact factor:   3.782


  23 in total

Review 1.  History of lung transplantation.

Authors:  Federico Venuta; Dirk Van Raemdonck
Journal:  J Thorac Dis       Date:  2017-12       Impact factor: 2.895

Review 2.  The Future of Lung Transplantation.

Authors:  Katherine A Young; Daniel F Dilling
Journal:  Chest       Date:  2018-08-29       Impact factor: 9.410

3.  Procedure Preference and Intention-to-Treat Outcomes after Listing for Lung Transplantation among U.S. Adults. A Cohort Study.

Authors:  Michaela R Anderson; Ashley Tabah; Arindam RoyChoudhury; David J Lederer
Journal:  Ann Am Thorac Soc       Date:  2019-02

Review 4.  Lung transplantation: a treatment option in end-stage lung disease.

Authors:  Marc Hartert; Omer Senbaklavacin; Bernhard Gohrbandt; Berthold M Fischer; Roland Buhl; Christian-Friedrich Vahld
Journal:  Dtsch Arztebl Int       Date:  2014-02-14       Impact factor: 5.594

5.  Variability in donor organ offer acceptance and lung transplantation survival.

Authors:  Michael S Mulvihill; Hui J Lee; Jeremy Weber; Ashley Y Choi; Morgan L Cox; Babatunde A Yerokun; Muath A Bishawi; Jacob Klapper; Maragatha Kuchibhatla; Matthew G Hartwig
Journal:  J Heart Lung Transplant       Date:  2020-01-21       Impact factor: 10.247

Review 6.  Does the use of extended criteria donors influence early and long-term results of lung transplantation?

Authors:  Marco Schiavon; Pierre-Emmanuel Falcoz; Nicola Santelmo; Gilbert Massard
Journal:  Interact Cardiovasc Thorac Surg       Date:  2011-11-25

Review 7.  Primary graft dysfunction.

Authors:  Yoshikazu Suzuki; Edward Cantu; Jason D Christie
Journal:  Semin Respir Crit Care Med       Date:  2013-07-02       Impact factor: 3.119

Review 8.  Lung donor selection criteria.

Authors:  John Chaney; Yoshikazu Suzuki; Edward Cantu; Victor van Berkel
Journal:  J Thorac Dis       Date:  2014-08       Impact factor: 2.895

9.  Organomatics and organometrics: Novel platforms for long-term whole-organ culture.

Authors:  Bote G Bruinsma; Martin L Yarmush; Korkut Uygun
Journal:  Technology (Singap World Sci)       Date:  2014-03

10.  Sequence of refusals for donor quality, organ utilization, and survival after lung transplantation.

Authors:  Eshita Singh; Marc Schecter; Christopher Towe; Raheel Rizwan; Bryant Roosevelt; James Tweddell; M Monir Hossain; David Morales; Farhan Zafar
Journal:  J Heart Lung Transplant       Date:  2018-08-17       Impact factor: 10.247

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