Literature DB >> 20059235

Whole-body, real-time preclinical imaging of quantum dot fluorescence with time-gated detection.

Andrzej May, Srabani Bhaumik, Sanjiv S Gambhir, Chun Zhan, Siavash Yazdanfar.   

Abstract

We describe a wide-field preclinical imaging system optimized for time-gated detection of quantum dot fluorescence emission. As compared to continuous wave measurements, image contrast was substantially improved by suppression of short-lifetime background autofluorescence. Real-time (8 frames/s) biological imaging of subcutaneous quantum dot injections is demonstrated simultaneously in multiple living mice.

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Year:  2009        PMID: 20059235      PMCID: PMC2801727          DOI: 10.1117/1.3269675

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN: 1083-3668            Impact factor:   3.170


  16 in total

1.  Fluorescence decay time of single semiconductor nanocrystals.

Authors:  Germar Schlegel; Jolanta Bohnenberger; Inga Potapova; Alf Mews
Journal:  Phys Rev Lett       Date:  2002-03-14       Impact factor: 9.161

2.  Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking.

Authors:  Maxime Dahan; Sabine Lévi; Camilla Luccardini; Philippe Rostaing; Béatrice Riveau; Antoine Triller
Journal:  Science       Date:  2003-10-17       Impact factor: 47.728

Review 3.  Quantum dots for live cells, in vivo imaging, and diagnostics.

Authors:  X Michalet; F F Pinaud; L A Bentolila; J M Tsay; S Doose; J J Li; G Sundaresan; A M Wu; S S Gambhir; S Weiss
Journal:  Science       Date:  2005-01-28       Impact factor: 47.728

4.  Solution control of radiative and nonradiative lifetimes: a novel contribution to quantum dot blinking suppression.

Authors:  Vasiliy Fomenko; David J Nesbitt
Journal:  Nano Lett       Date:  2007-12-21       Impact factor: 11.189

5.  A comparison between a time domain and continuous wave small animal optical imaging system.

Authors:  S Keren; O Gheysens; C S Levin; S S Gambhir
Journal:  IEEE Trans Med Imaging       Date:  2008-01       Impact factor: 10.048

6.  In vivo simultaneous monitoring of two fluorophores with lifetime contrast using a full-field time domain system.

Authors:  David J Hall; Ulas Sunar; Salman Farshchi-Heydari; Sung-Ho Han
Journal:  Appl Opt       Date:  2009-04-01       Impact factor: 1.980

7.  Stroboscopic fluorescence lifetime imaging.

Authors:  Mark D Holton; Oscar R Silvestre; Rachel J Errington; Paul J Smith; Daniel R Matthews; Paul Rees; Huw D Summers
Journal:  Opt Express       Date:  2009-03-30       Impact factor: 3.894

8.  In vivo cancer targeting and imaging with semiconductor quantum dots.

Authors:  Xiaohu Gao; Yuanyuan Cui; Richard M Levenson; Leland W K Chung; Shuming Nie
Journal:  Nat Biotechnol       Date:  2004-07-18       Impact factor: 54.908

9.  Predicting in vivo fluorescence lifetime behavior of near-infrared fluorescent contrast agents using in vitro measurements.

Authors:  Walter J Akers; Mikhail Y Berezin; Hyeran Lee; Samuel Achilefu
Journal:  J Biomed Opt       Date:  2008 Sep-Oct       Impact factor: 3.170

10.  Fluorescence lifetime imaging of quantum dot labeled DNA microarrays.

Authors:  Gerard Giraud; Holger Schulze; Till T Bachmann; Colin J Campbell; Andrew R Mount; Peter Ghazal; Mizanur R Khondoker; Alan J Ross; Stuart W J Ember; Ilenia Ciani; Chaker Tlili; Anthony J Walton; Jonathan G Terry; Jason Crain
Journal:  Int J Mol Sci       Date:  2009-04-24       Impact factor: 6.208

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  7 in total

1.  Low-frequency wide-field fluorescence lifetime imaging using a high-power near-infrared light-emitting diode light source.

Authors:  Sylvain Gioux; Stephen J Lomnes; Hak Soo Choi; John V Frangioni
Journal:  J Biomed Opt       Date:  2010 Mar-Apr       Impact factor: 3.170

Review 2.  Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation.

Authors:  Sylvain Gioux; Hak Soo Choi; John V Frangioni
Journal:  Mol Imaging       Date:  2010-10       Impact factor: 4.488

3.  In vivo validation of quantitative frequency domain fluorescence tomography.

Authors:  Yuting Lin; Michael Ghijsen; Orhan Nalcioglu; Gultekin Gulsen
Journal:  J Biomed Opt       Date:  2012-12       Impact factor: 3.170

4.  Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging.

Authors:  Ahmet Erten; David Hall; Carl Hoh; Hop S Tran Cao; Sharmeela Kaushal; Sadik Esener; Robert M Hoffman; Michael Bouvet; James Chen; Santosh Kesari; Milan Makale
Journal:  J Biomed Opt       Date:  2010 Nov-Dec       Impact factor: 3.170

5.  Highly efficient detection in fluorescence tomography of quantum dots using time-gated acquisition and ultrafast pulsed laser.

Authors:  Xiaofeng Zhang; Cristian T Badea
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2011-01-23

6.  Assembly and targeting of liposomal nanoparticles encapsulating quantum dots.

Authors:  Rajesh Mukthavaram; Wolf Wrasidlo; David Hall; Santosh Kesari; Milan Makale
Journal:  Bioconjug Chem       Date:  2011-08-01       Impact factor: 4.774

7.  Imaging workflow and calibration for CT-guided time-domain fluorescence tomography.

Authors:  Kenneth M Tichauer; Robert W Holt; Fadi El-Ghussein; Qun Zhu; Hamid Dehghani; Frederic Leblond; Brian W Pogue
Journal:  Biomed Opt Express       Date:  2011-10-05       Impact factor: 3.732

  7 in total

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