INTRODUCTION: The Improving Outcomes Guidance (IOG) for patients with carcinoma of the penis states that treatment should be provided supraregionally to populations of 4 million or greater who treat over 25 cases of penis cancer each year. This study assesses the impact of this guidance on the management and outcomes of patients with the disease in our region. PATIENTS AND METHODS: We retrospectively compared the records of 44 patients with carcinoma of the penis treated in our institution between 1969 and 1990 with 101 patients treated between 2002 and 2006, i.e. after supraregional centralisation of the service. RESULTS: There was no significant change in the stage or grade of the tumours. However, the results show that, in modern times, there was a significant increase in the amount of penis-preserving and nodal surgery as well as a fall in mortality. The improved survival is greatest in patients with poorly-differentiated disease who may, therefore, have benefited from aggressive nodal surgery. CONCLUSIONS: The centralisation of surgery for carcinoma of the penis results in improved outcomes both in terms of penis preservation and improved survival and this supports the IOG guidance.
INTRODUCTION: The Improving Outcomes Guidance (IOG) for patients with carcinoma of the penis states that treatment should be provided supraregionally to populations of 4 million or greater who treat over 25 cases of penis cancer each year. This study assesses the impact of this guidance on the management and outcomes of patients with the disease in our region. PATIENTS AND METHODS: We retrospectively compared the records of 44 patients with carcinoma of the penis treated in our institution between 1969 and 1990 with 101 patients treated between 2002 and 2006, i.e. after supraregional centralisation of the service. RESULTS: There was no significant change in the stage or grade of the tumours. However, the results show that, in modern times, there was a significant increase in the amount of penis-preserving and nodal surgery as well as a fall in mortality. The improved survival is greatest in patients with poorly-differentiated disease who may, therefore, have benefited from aggressive nodal surgery. CONCLUSIONS: The centralisation of surgery for carcinoma of the penis results in improved outcomes both in terms of penis preservation and improved survival and this supports the IOG guidance.
Authors: Jong Kil Nam; Dong Hoon Lee; Sung Woo Park; Sung Chul Kam; Ki Soo Lee; Tae Hyo Kim; Taek Sang Kim; Cheol Kyu Oh; Hyun Jun Park; Tae Nam Kim Journal: World J Mens Health Date: 2017-04 Impact factor: 5.400
Authors: Maximilian Pallauf; Marie C Hempel; Marie C Hupe; Matthias May; Marlene Haccius; Dorothea Weckermann; Steffen Lebentrau; Bernd Hoschke; Ulrike Necknig; Jesco Pfitzenmaier; Lukas Manka; Philipp Nuhn; Peter Törzsök; Lukas Lusuardi; Axel S Merseburger Journal: Adv Ther Date: 2020-10-10 Impact factor: 3.845
Authors: Steffen Lebentrau; Gamal Anton Wakileh; Martin Schostak; Hans-Peter Schmid; Rodrigo Suarez-Ibarrola; Axel S Merseburger; Georg C Hutterer; Ulrike H Necknig; Michael Rink; Martin Bögemann; Luis Alex Kluth; Armin Pycha; Maximilian Burger; Sabine D Brookman-May; Johannes Bründl; Matthias May Journal: Front Oncol Date: 2021-11-29 Impact factor: 6.244
Authors: Marco Bandini; Mohamed Ahmed; Giuseppe Basile; Nicholas Watkin; Viraj Master; Yao Zhu; Gagan Prakash; Alejandro Rodriguez; Mbaaga K Ssebakumba; Riccardo Leni; Giuseppe Ottone Cirulli; Ben Ayres; Rachel Compitello; Filippo Pederzoli; Pankaj M Joshi; Sanjay B Kulkarni; Francesco Montorsi; Guru Sonpavde; Andrea Necchi; Philippe E Spiess Journal: Nat Rev Urol Date: 2021-12-22 Impact factor: 16.430