Literature DB >> 20054671

Sustained release tablets containing soluble polymethacrylates: comparison with tableted polymethacrylate IPEC polymers.

Wasfy M Obeidat1, Alaa H Abuznait, Al-Sayed A Sallam.   

Abstract

The objective of this study was to compare a novel sustained release tablet formulation that has the potential to be used for drugs of different physicochemical properties using a binary mixture of polymethacrylate polymers in their salt forms with the polymethacrylate interpolyelectrolyte complex (IPEC) tablets in terms of drug release and compactness. Also, we aimed to compare this formulation with an IPEC tablet in terms of drug release. Tablets prepared using Eudragit E-Citrate and Eudragit L-Sodium were more convenient, easier to prepare, and showed better sustained release and compactness characteristics compared to IPEC tablets of similar concentrations and preparation methods.

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Year:  2010        PMID： 20054671      PMCID： PMC2850471          DOI： 10.1208/s12249-009-9348-5

Source DB:  PubMed          Journal:  AAPS PharmSciTech        ISSN： 1530-9932            Impact factor:   3.246


  16 in total

1.  Artificial neural networks in the modeling and optimization of aspirin extended release tablets with Eudragit L 100 as matrix substance.

Authors:  Svetlana Ibrić; Milica Jovanović; Zorica Djurić; Jelena Parojcić; Slobodan D Petrović; Ljiljana Solomun; Biljana Stupar
Journal:  AAPS PharmSciTech       Date:  2003       Impact factor: 3.246

Review 2.  Hydrogels for oral delivery of therapeutic proteins.

Authors:  Nicholas A Peppas; Kristy M Wood; James O Blanchette
Journal:  Expert Opin Biol Ther       Date:  2004-06       Impact factor: 4.388

3.  Characterization of Eudragit E100/Carbomer 940P interpolyelectrolyte complexes using swellability measurements.

Authors:  T V Kabanova; E R Zhdanova; R I Moustafine
Journal:  J Control Release       Date:  2006-11-28       Impact factor: 9.776

4.  Swellability testing of chitosan/Eudragit L100-55 interpolyelectrolyte complexes for colonic drug delivery.

Authors:  E B Margulis; R I Moustafine
Journal:  J Control Release       Date:  2006-11-28       Impact factor: 9.776

5.  Design of new polymer carriers based of Eudragit E PO/Eudragit L100-55 interpolyelectrolyte complexes using swellability measurements.

Authors:  R I Moustafine; O V Bobyleva
Journal:  J Control Release       Date:  2006-11-28       Impact factor: 9.776

6.  Eudragit E as coating material for the pH-controlled drug release in the topical treatment of inflammatory bowel disease (IBD).

Authors:  C S Leopold; D Eikeler
Journal:  J Drug Target       Date:  1998       Impact factor: 5.121

7.  Manufacture of slow-release matrix granules by wet granulation with an aqueous dispersion of quaternary poly(meth)acrylates in the fluidized bed.

Authors:  Guido Radtke; Klaus Knop; Bernhard C Lippold
Journal:  Drug Dev Ind Pharm       Date:  2002-11       Impact factor: 3.225

8.  Physicochemical characterization and drug release properties of Eudragit E PO/Eudragit L 100-55 interpolyelectrolyte complexes.

Authors:  Rouslan I Moustafine; Igor M Zaharov; Vera A Kemenova
Journal:  Eur J Pharm Biopharm       Date:  2005-12-27       Impact factor: 5.571

9.  In vitro evaluation of a system for pH-controlled peroral delivery of metformin.

Authors:  G Di Colo; S Falchi; Y Zambito
Journal:  J Control Release       Date:  2002-04-23       Impact factor: 9.776

10.  Incorporation of polymeric nanoparticles into solid dosage forms.

Authors:  C Schmidt; R Bodmeier
Journal:  J Control Release       Date:  1999-02-01       Impact factor: 9.776
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  3 in total

1.  Accelerated healing of cutaneous leishmaniasis in non-healing BALB/c mice using water soluble amphotericin B-polymethacrylic acid.

Authors:  Karina Corware; Debra Harris; Ian Teo; Matthew Rogers; Kikkeri Naresh; Ingrid Müller; Sunil Shaunak
Journal:  Biomaterials       Date:  2011-07-31       Impact factor: 12.479

2.  Nebulised amphotericin B-polymethacrylic acid nanoparticle prophylaxis prevents invasive aspergillosis.

Authors:  Khojasteh Shirkhani; Ian Teo; Darius Armstrong-James; Sunil Shaunak
Journal:  Nanomedicine       Date:  2015-03-16       Impact factor: 5.307

3.  Influence of different types of low substituted hydroxypropyl cellulose on tableting, disintegration, and floating behaviour of floating drug delivery systems.

Authors:  Péter Diós; Tivadar Pernecker; Sándor Nagy; Szilárd Pál; Attila Dévay
Journal:  Saudi Pharm J       Date:  2014-10-07       Impact factor: 4.330
  3 in total

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