Literature DB >> 20050926

Genetic influences on 'environmental' factors.

A A E Vinkhuyzen1, S van der Sluis, E J C de Geus, D I Boomsma, D Posthuma.   

Abstract

Childhood environment, social environment and behavior, leisure time activities and life events have been hypothesized to contribute to individual differences in cognitive abilities and physical and emotional well-being. These factors are often labeled 'environmental', suggesting they shape but not reflect individual differences in behavior. The aim of this study is to test the hypothesis that these factors are not randomly distributed across the population but reflect heritable individual differences. Self-report data on Childhood Environment, Social Environment and Behavior, Leisure Time Activities and Life Events were obtained from 560 adult twins and siblings (mean age 47.11 years). Results clearly show considerable genetic influences on these factors with mean broad heritability of 0.49 (0.00-0.87). This suggests that what we think of as measures of 'environment' are better described as external factors that might be partly under genetic control. Understanding causes of individual differences in external factors may aid in clarifying the intricate nature between genetic and environmental influences on complex traits.

Mesh:

Year:  2009        PMID: 20050926     DOI: 10.1111/j.1601-183X.2009.00554.x

Source DB:  PubMed          Journal:  Genes Brain Behav        ISSN: 1601-183X            Impact factor:   3.449


  23 in total

Review 1.  Unravelling the effects of the environment and host genotype on the gut microbiome.

Authors:  Aymé Spor; Omry Koren; Ruth Ley
Journal:  Nat Rev Microbiol       Date:  2011-04       Impact factor: 60.633

Review 2.  The continuing value of twin studies in the omics era.

Authors:  Jenny van Dongen; P Eline Slagboom; Harmen H M Draisma; Nicholas G Martin; Dorret I Boomsma
Journal:  Nat Rev Genet       Date:  2012-07-31       Impact factor: 53.242

3.  Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD.

Authors:  Rachel Yehuda; Janine D Flory; Laura C Pratchett; Joseph Buxbaum; Marcus Ising; Florian Holsboer
Journal:  Psychopharmacology (Berl)       Date:  2010-08-13       Impact factor: 4.530

Review 4.  Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature.

Authors:  Eshim S Jami; Anke R Hammerschlag; Meike Bartels; Christel M Middeldorp
Journal:  Transl Psychiatry       Date:  2021-04-01       Impact factor: 6.222

5.  Expanding the environment: gene × school-level SES interaction on reading comprehension.

Authors:  Sara A Hart; Brooke Soden; Wendy Johnson; Christopher Schatschneider; Jeanette Taylor
Journal:  J Child Psychol Psychiatry       Date:  2013-06-01       Impact factor: 8.982

6.  Widespread covariation of early environmental exposures and trait-associated polygenic variation.

Authors:  E Krapohl; L J Hannigan; J-B Pingault; H Patel; N Kadeva; C Curtis; G Breen; S J Newhouse; T C Eley; P F O'Reilly; R Plomin
Journal:  Proc Natl Acad Sci U S A       Date:  2017-10-16       Impact factor: 11.205

7.  inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains.

Authors:  Matthew R Olm; Alexander Crits-Christoph; Keith Bouma-Gregson; Brian A Firek; Michael J Morowitz; Jillian F Banfield
Journal:  Nat Biotechnol       Date:  2021-01-18       Impact factor: 68.164

8.  Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs.

Authors:  E Krapohl; R Plomin
Journal:  Mol Psychiatry       Date:  2015-03-10       Impact factor: 15.992

9.  Genetic origin of the relationship between parental negativity and behavior problems from early childhood to adolescence: a longitudinal genetically sensitive study.

Authors:  Silvia Alemany; Frühling V Rijsdijk; Claire Margaret Alison Haworth; Lourdes Fañanás; Robert Plomin
Journal:  Dev Psychopathol       Date:  2013-05

10.  The role of parental genotype in predicting offspring years of education: evidence for genetic nurture.

Authors:  Emily A Willoughby; Matt McGue; William G Iacono; Aldo Rustichini; James J Lee
Journal:  Mol Psychiatry       Date:  2019-08-23       Impact factor: 13.437

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.