Literature DB >> 20047330

Small molecules and stem cells. Potency and lineage commitment: the new quest for the fountain of youth.

Agnès I Lukaszewicz1, Michael K McMillan, Michael Kahn.   

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Year:  2010        PMID: 20047330      PMCID: PMC2865574          DOI: 10.1021/jm901361d

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  112 in total

Review 1.  The Hedgehog and Wnt signalling pathways in cancer.

Authors:  J Taipale; P A Beachy
Journal:  Nature       Date:  2001-05-17       Impact factor: 49.962

2.  Isolation of a stem cell for neurons and glia from the mammalian neural crest.

Authors:  D L Stemple; D J Anderson
Journal:  Cell       Date:  1992-12-11       Impact factor: 41.582

Review 3.  Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current views.

Authors:  Donald G Phinney; Darwin J Prockop
Journal:  Stem Cells       Date:  2007-09-27       Impact factor: 6.277

4.  A small molecule primes embryonic stem cells for differentiation.

Authors:  Shoutian Zhu; Heiko Wurdak; Jian Wang; Costas A Lyssiotis; Eric C Peters; Charles Y Cho; Xu Wu; Peter G Schultz
Journal:  Cell Stem Cell       Date:  2009-05-08       Impact factor: 24.633

5.  A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.

Authors:  Li Ding; Maciej Paszkowski-Rogacz; Anja Nitzsche; Mikolaj Michal Slabicki; Anne-Kristin Heninger; Ingrid de Vries; Ralf Kittler; Magno Junqueira; Andrej Shevchenko; Herbert Schulz; Norbert Hubner; Michael Xavier Doss; Agapios Sachinidis; Juergen Hescheler; Roberto Iacone; Konstantinos Anastassiadis; A Francis Stewart; M Teresa Pisabarro; Antonio Caldarelli; Ina Poser; Mirko Theis; Frank Buchholz
Journal:  Cell Stem Cell       Date:  2009-04-02       Impact factor: 24.633

6.  High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.

Authors:  Sabrina C Desbordes; Dimitris G Placantonakis; Anthony Ciro; Nicholas D Socci; Gabsang Lee; Hakim Djaballah; Lorenz Studer
Journal:  Cell Stem Cell       Date:  2008-06-05       Impact factor: 24.633

7.  Induced pluripotent stem cells generated without viral integration.

Authors:  Matthias Stadtfeld; Masaki Nagaya; Jochen Utikal; Gordon Weir; Konrad Hochedlinger
Journal:  Science       Date:  2008-09-25       Impact factor: 47.728

8.  A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected].

Authors:  Katayoon H Emami; Cu Nguyen; Hong Ma; Dae Hoon Kim; Kwang Won Jeong; Masakatsu Eguchi; Randall T Moon; Jia-Ling Teo; Se Woong Oh; Hak Yeop Kim; Sung Hwan Moon; Jong Ryul Ha; Michael Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205

9.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors:  Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal:  Nat Biotechnol       Date:  2007-11-30       Impact factor: 54.908

10.  Lineage-specific requirements of beta-catenin in neural crest development.

Authors:  Lisette Hari; Véronique Brault; Maurice Kléber; Hye-Youn Lee; Fabian Ille; Rainer Leimeroth; Christian Paratore; Ueli Suter; Rolf Kemler; Lukas Sommer
Journal:  J Cell Biol       Date:  2002-12-09       Impact factor: 10.539

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  12 in total

Review 1.  Generation of pluripotent stem cells without the use of genetic material.

Authors:  Akon Higuchi; Qing-Dong Ling; S Suresh Kumar; Murugan A Munusamy; Abdullah A Alarfaj; Yung Chang; Shih-Hsuan Kao; Ke-Chen Lin; Han-Chow Wang; Akihiro Umezawa
Journal:  Lab Invest       Date:  2014-11-03       Impact factor: 5.662

Review 2.  The Role of the Microenvironment in Controlling the Fate of Bioprinted Stem Cells.

Authors:  Lauren N West-Livingston; Jihoon Park; Sang Jin Lee; Anthony Atala; James J Yoo
Journal:  Chem Rev       Date:  2020-06-19       Impact factor: 60.622

Review 3.  Can we safely target the WNT pathway?

Authors:  Michael Kahn
Journal:  Nat Rev Drug Discov       Date:  2014-07       Impact factor: 84.694

4.  Hairy and Enhancer of Split 6 (Hes6) Deficiency in Mouse Impairs Neuroblast Differentiation in Dentate Gyrus Without Affecting Cell Proliferation and Integration into Mature Neurons.

Authors:  Sung Min Nam; Yo Na Kim; Jong Whi Kim; Dong Soo Kyeong; Seo Hyun Lee; Yeri Son; Jae Hoon Shin; Jaesang Kim; Sun Shin Yi; Yeo Sung Yoon; Je Kyung Seong
Journal:  Cell Mol Neurobiol       Date:  2015-06-24       Impact factor: 5.046

Review 5.  Molecular characterization of heterogeneous mesenchymal stem cells with single-cell transcriptomes.

Authors:  Zhongjun Li; Chao Zhang; Leslie P Weiner; Yiqiang Zhang; Jiang F Zhong
Journal:  Biotechnol Adv       Date:  2012-12-21       Impact factor: 14.227

6.  Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.

Authors:  Kouichi Hasegawa; Shin-ya Yasuda; Jia-Ling Teo; Cu Nguyen; Michael McMillan; Chih-Lin Hsieh; Hirofumi Suemori; Norio Nakatsuji; Masashi Yamamoto; Tomoyuki Miyabayashi; Carolyn Lutzko; Martin F Pera; Michael Kahn
Journal:  Stem Cells Transl Med       Date:  2011-12-07       Impact factor: 6.940

7.  Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model.

Authors:  Ena Ray Banerjee; Michael A Laflamme; Thalia Papayannopoulou; Michael Kahn; Charles E Murry; William R Henderson
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

8.  Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin.

Authors:  King Chi Chan; Lai Sheung Chan; Joseph Chok Yan Ip; Carman Lo; Timothy Tak Chun Yip; Roger Kai Cheong Ngan; Ricky Ngok Shun Wong; Kwok Wai Lo; Wai Tong Ng; Anne Wing Mui Lee; George Sai Wah Tsao; Michael Kahn; Maria Li Lung; Nai Ki Mak
Journal:  Sci Rep       Date:  2015-04-21       Impact factor: 4.379

9.  Phenotypic Assessment and the Discovery of Topiramate.

Authors:  Bruce E Maryanoff
Journal:  ACS Med Chem Lett       Date:  2016-06-13       Impact factor: 4.345

10.  The small molecule Wnt signaling modulator ICG-001 improves contractile function in chronically infarcted rat myocardium.

Authors:  Tomoyo Sasaki; Hyosook Hwang; Cu Nguyen; Robert A Kloner; Michael Kahn
Journal:  PLoS One       Date:  2013-09-12       Impact factor: 3.240

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