| Literature DB >> 20045145 |
Holger Stepan1, Susan Kralisch, Katrin Klostermann, Susanne Schrey, Constanze Reisenbüchler, Michael Verlohren, Hans-Joachim Verlohren, Kathrin Drynda, Matthias Blüher, Michael Stumvoll, Jürgen Kratzsch, Peter Kovacs, Mathias Fasshauer.
Abstract
The objective of the study was to investigate serum levels of the insulin-sensitizing adipokine vaspin in patients with gestational diabetes mellitus (GDM) and preeclampsia (PE) as compared with healthy controls of similar gestational age. Vaspin serum levels were quantified by enzyme-linked immunosorbent assay in control (n = 102), GDM (n = 40), and PE (n = 22) subjects. Median maternal vaspin concentrations were not significantly different in GDM, PE, and control subjects. Furthermore, vaspin did not significantly correlate to clinical and biochemical measures of renal function, glucose, and lipid metabolism, as well as inflammation. Circulating vaspin levels are not significantly different between GDM, PE, and control subjects and do not correlate with insulin sensitivity in pregnant subjects.Entities:
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Year: 2009 PMID： 20045145 DOI： 10.1016/j.metabol.2009.11.001
Source DB: PubMed Journal: Metabolism ISSN： 0026-0495 Impact factor: 8.694