Literature DB >> 20041710

Highly efficient Cu(I)-catalyzed synthesis of N-heterocycles through a cyclization-triggered addition of alkynes.

Junbin Han1, Bo Xu, Gerald B Hammond.   

Abstract

An aminoalkyne (terminal or internal) and a terminal alkyne furnish functionalized five-, six-, and seven-membered N-heterocycles in excellent yields via a Cu(I)-catalyzed, one-pot, tandem hydroamination/alkynylation process.

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Year:  2010        PMID： 20041710     DOI： 10.1021/ja908883n

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  6 in total

1.  Accessing alternative reaction pathways of the intermolecular condensation between homo-propargyl alcohols and terminal alkynes through divergent gold catalysis.

Authors:  Courtney A Smith; Stephen E Motika; Lukasz Wojtas; Xiaodong Shi
Journal:  Chem Commun (Camb)       Date:  2017-02-16       Impact factor: 6.222

2.  Synthesis of Cyclic α-Aminophosphonates through Copper Catalyzed Enamine Activation.

Authors:  Junbin Han; Robert S Paton; Bo Xu; Gerald B Hammond
Journal:  Synthesis (Stuttg)       Date:  2013-02-01       Impact factor: 3.157

3.  Synthesis of Pyrrolidines and Pyrroles via Tandem Amination/Cyanation/Alkylation and Amination/Oxidation Sequences.

Authors:  Junbin Han; Zhichao Lu; Gerald B Hammond; Bo Xu
Journal:  European J Org Chem       Date:  2014-09-01

4.  A simple, multidimensional approach to high-throughput discovery of catalytic reactions.

Authors:  Daniel W Robbins; John F Hartwig
Journal:  Science       Date:  2011-09-09       Impact factor: 47.728

5.  Pinene-derived iminodiacetic acid (PIDA): a powerful ligand for stereoselective synthesis and iterative cross-coupling of C(sp3) boronate building blocks.

Authors:  Junqi Li; Martin D Burke
Journal:  J Am Chem Soc       Date:  2011-08-10       Impact factor: 15.419

6.  A Copper-Catalyzed Tandem Cyclization Reaction of Aminoalkynes with Alkynes for the Construction of Tetrahydropyrrolo[1,2-a]quinolines Scaffold.

Authors:  Can-Liang Ma; Jin-Hao Zhao; Yong Yang; Min-Kui Zhang; Chao Shen; Rong Sheng; Xiao-Wu Dong; Yong-Zhou Hu
Journal:  Sci Rep       Date:  2017-11-30       Impact factor: 4.379
  6 in total

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