Literature DB >> 20040588

GWAF: an R package for genome-wide association analyses with family data.

Ming-Huei Chen1, Qiong Yang.   

Abstract

SUMMARY: GWAF, Genome-Wide Association analyses with Family, is an R package designed for GWAF. It implements association tests between a batch of genotyped or imputed single nucleotide polymorphisms (SNPs) and a binary or continuous trait with user specified genetic model, and generates informative results from the analyses. In addition, GWAF provides functions to visualize results. We evaluated GWAF using a simulated continuous trait and a binary trait dichotomized from the simulated continuous trait with real genotype data from the Framingham Heart Study's SNP Health Association Resource project.

Mesh：

Year:  2009        PMID： 20040588      PMCID： PMC2852219          DOI： 10.1093/bioinformatics/btp710

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  3 in total

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3.  Multipoint quantitative-trait linkage analysis in general pedigrees.

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  3 in total
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9.  Linkage Analysis of High-density SNPs Confirms Keratoconus Locus at 5q Chromosomal Region.

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