Literature DB >> 20036609

Head and neck cancer surgery in the elderly--does age influence the postoperative course?

Pedro Ricardo Milet1, Yann Mallet, Sophie El Bedoui, Nicolas Penel, Véronique Servent, Jean-Louis Lefebvre.   

Abstract

There are few data focusing on postoperative course after major head and neck cancer surgery in the elderly compared with the younger population. The aim of this study was to assess the impact of age on postoperative outcomes. At hospital admission, we prospectively collected data from 261 patients separated into two groups with regard to their age (those >or= 70 years and those < 70 years). Twenty-nine of them were over 70 years old. Median length of stay was similar in both populations (22 vs. 21 days, p=0.66). Incidence of severe postoperative complications was similar: surgical site infection (6/29 vs. 89/232, p=0.77), pneumonia (4/29 vs. 29/232, p=0.13) and infection caused by multi-resistant pathogens (1/29 vs. 14/232, p=0.08). There was no significant increase in postoperative deaths (4/29 vs. 6/232, p=0.12). The impact of age on postoperative deaths was assessed after adjustment for potential risk factors. In a logistic regression model, postoperative death risk remained insignificantly increased in the elderly (adjusted Odds Ratio=3.3 [0.7-14.9], p=0.22). In our experience, the postoperative course in elderly patients is not significantly different from that than in younger patients.

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Year:  2009        PMID: 20036609     DOI: 10.1016/j.oraloncology.2009.10.002

Source DB:  PubMed          Journal:  Oral Oncol        ISSN: 1368-8375            Impact factor:   5.337


  10 in total

1.  [Clinical aspects of transoral laser surgery and neck dissection for oro- and hypopharyngeal cancer in elderly patients].

Authors:  A Teymoortash; J Kunzmann; H Daniel; N Franke; J A Werner; S Hoch
Journal:  HNO       Date:  2014-05       Impact factor: 1.284

Review 2.  Squamous cell carcinoma of the head and neck in the elderly.

Authors:  Jasenka Gugić; Primož Strojan
Journal:  Rep Pract Oncol Radiother       Date:  2012-08-10

3.  [Head and neck cancer in the elderly-current aspects].

Authors:  B Höing; S Lang; M Stuschke; S Hansen
Journal:  HNO       Date:  2020-03       Impact factor: 1.284

4.  Analysis of outcome for elderly patients after microvascular flap surgery: a monocentric retrospective cohort study.

Authors:  Henning Hanken; Evgeny Barsukov; Friedemann Göhler; Susanne Sehner; Ralf Smeets; Benedicta Beck-Broichsitter; Max Heiland; Kilian Kreutzer; Alexander Gröbe
Journal:  Clin Oral Investig       Date:  2019-05-08       Impact factor: 3.573

5.  Incidence and risk factors for morbidity and mortality in elderly head and neck cancer patients undergoing major oncological surgery.

Authors:  Shin Hyuk Yoo; Jong-Lyel Roh; Seung-Ho Choi; Soon Yuhl Nam; Sang Yoon Kim
Journal:  J Cancer Res Clin Oncol       Date:  2016-03-16       Impact factor: 4.553

6.  Free flap reconstruction for head and neck cancer can be safely performed in both young and elderly patients after careful patient selection.

Authors:  Thomas T A Peters; Sophie F Post; Boukje A C van Dijk; Jan L N Roodenburg; Bernard F A M van der Laan; Paul M N Werker; Gyorgy B Halmos
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-09-13       Impact factor: 2.503

Review 7.  Treatment of older patients with head and neck cancer: a review.

Authors:  Noam A VanderWalde; Mary Fleming; Jared Weiss; Bhishamjit S Chera
Journal:  Oncologist       Date:  2013-05-01

8.  The role of age in treatment decisions for oral cavity squamous cell carcinoma: Analysis of the National Cancer Database.

Authors:  Thomas F Barrett; Angela L Mazul; Katelyn O Stepan; C Burton Wood; Randall C Paniello; Jose P Zevallos; Sean Massa; Ryan S Jackson; Nicole C Schmitt; Joseph Zenga; Stephen Y Kang; Patrik Pipkorn; Jason T Rich; Sidharth V Puram
Journal:  Oral Oncol       Date:  2021-05-12       Impact factor: 5.972

9.  The association, clinicopathological significance, and diagnostic value of CDH1 promoter methylation in head and neck squamous cell carcinoma: a meta-analysis of 23 studies.

Authors:  Zhisen Shen; Chongchang Zhou; Jinyun Li; Hongxia Deng; Qun Li; Jian Wang
Journal:  Onco Targets Ther       Date:  2016-10-31       Impact factor: 4.147

10.  Diagnostic and therapeutic features associated with modification of quality-of-life's outcomes between one and six months after major surgery for head and neck cancer.

Authors:  Margherita Gobbo; Federica Bullo; Giuseppe Perinetti; Annalisa Gatto; Giulia Ottaviani; Matteo Biasotto; Giancarlo Tirelli
Journal:  Braz J Otorhinolaryngol       Date:  2015-12-18
  10 in total

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