Literature DB >> 20033654

KIR genotyping by multiplex PCR-SSP.

Smita Kulkarni1, Maureen P Martin, Mary Carrington.   

Abstract

Diversity across KIR haplotypes stems from differences in numbers of inhibitory and activating receptors, as well as allelic polymorphism of individual genes. The KIR locus has undergone large expansions and contractions over time and is believed to be coevolving with genes encoding its HLA class I ligands located within the MHC locus. KIR and HLA compound genotypes have been associated with susceptibility to or protection from infectious, autoimmune, reproductive, and malignant disorders. We describe here a simple and reliable multiplex PCR-SSP (sequence-specific priming) method for relatively rapid and inexpensive genotyping of 15 KIR genes using standard agarose gel electrophoresis.

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Year:  2010        PMID: 20033654      PMCID: PMC3464904          DOI: 10.1007/978-1-60761-362-6_25

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  22 in total

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Review 3.  The biology of human natural killer-cell subsets.

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5.  Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell-mediated lysis is inversely correlated with HLA class I antigen expression.

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6.  Genetic control of human NK cell repertoire.

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Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-25       Impact factor: 11.205

9.  Cutting edge: expansion of the KIR locus by unequal crossing over.

Authors:  Maureen P Martin; Arman Bashirova; James Traherne; John Trowsdale; Mary Carrington
Journal:  J Immunol       Date:  2003-09-01       Impact factor: 5.422

Review 10.  Biology of natural killer cells.

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Journal:  Adv Immunol       Date:  1989       Impact factor: 3.543

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  27 in total

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2.  CD8αα homodimers function as a coreceptor for KIR3DL1.

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3.  HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C12:02/C14:03.

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Journal:  Cell Rep       Date:  2016-11-22       Impact factor: 9.423

4.  Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis.

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Journal:  HLA       Date:  2018-12       Impact factor: 4.513

5.  Diversity of the KIR gene cluster in an urban Brazilian population.

Authors:  D G Augusto; L Zehnder-Alves; M R Pincerati; M P Martin; M Carrington; Maria Luiza Petzl-Erler
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6.  A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.

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7.  16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands.

Authors:  J A Hollenbach; D G Augusto; C Alaez; L Bubnova; I Fae; G Fischer; F F Gonzalez-Galarza; C Gorodezky; L Karabon; P Kusnierczyk; J Noble; O Rickards; C Roberts; M Schaffer; L Shi; S Tavoularis; E Trachtenberg; Y Yao; D Middleton
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8.  The differential impact of natural killer (NK) cell education via KIR2DL3 and KIR3DL1 on CCL4 secretion in the context of in-vitro HIV infection.

Authors:  I Lisovsky; G Isitman; A Tremblay-McLean; R Song; S DaFonseca; B Lebouchẻ; J-P Routy; J Bruneau; N F Bernard
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9.  Killer cell immunoglobulin-like receptor gene cluster predisposes to susceptibility to B-cell acute lymphoblastic leukemia in Chinese children.

Authors:  Mingyan Jiang; Xia Guo; Lixing Yuan; Ju Gao; Li Huo; Qiang Li
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10.  In contrast to HIV, KIR3DS1 does not influence outcome in HTLV-1 retroviral infection.

Authors:  Geraldine M O'Connor; Nafisa-Katrin Seich Al Basatena; Viviana Olavarria; Aidan MacNamara; Alison Vine; Qi Ying; Michie Hisada; Bernardo Galvão-Castro; Becca Asquith; Daniel W McVicar
Journal:  Hum Immunol       Date:  2012-05-17       Impact factor: 2.850

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