BACKGROUND: There are difficulties in transcatheter closure of patent ductus arteriosus (PDA) in infants. METHODS AND RESULTS: The 46 infants (mean age 6.2+/-2.7 months; mean body weight 6.3+/-1.6 kg) who underwent PDA closure using the Amplatzer duct occluder (ADO). The indication for using an ADO was a ductus diameter > or =2.5 or 3 mm. Device diameter selected was 1-3 mm larger than ductal diameter. The mean systolic pulmonary artery pressure was 40.9+/-18.2 mmHg. The mean Qp/Qs ratio was 3.1+/-1.2. The mean ductus diameter was 3.3+/-0.8 mm. ADO was successfully deployed in 45 patients. Failure occurred in 1 case. The mean diameter of device used was 5.4+/-1.1 mm. No severe complications occurred. At the 1-month echocardiographic follow-up, a small residual shunt was present in 4 of 45 patients and had disappeared in all 4 patients at the 3-month follow-up. One patient developed a moderate degree of left ventricular outflow tract obstruction 2.3 years after the procedure. CONCLUSIONS: Transcatheter closure of PDA in infants using the ADO is a safe and effective method.
BACKGROUND: There are difficulties in transcatheter closure of patent ductus arteriosus (PDA) in infants. METHODS AND RESULTS: The 46 infants (mean age 6.2+/-2.7 months; mean body weight 6.3+/-1.6 kg) who underwent PDA closure using the Amplatzer duct occluder (ADO). The indication for using an ADO was a ductus diameter > or =2.5 or 3 mm. Device diameter selected was 1-3 mm larger than ductal diameter. The mean systolic pulmonary artery pressure was 40.9+/-18.2 mmHg. The mean Qp/Qs ratio was 3.1+/-1.2. The mean ductus diameter was 3.3+/-0.8 mm. ADO was successfully deployed in 45 patients. Failure occurred in 1 case. The mean diameter of device used was 5.4+/-1.1 mm. No severe complications occurred. At the 1-month echocardiographic follow-up, a small residual shunt was present in 4 of 45 patients and had disappeared in all 4 patients at the 3-month follow-up. One patient developed a moderate degree of left ventricular outflow tract obstruction 2.3 years after the procedure. CONCLUSIONS: Transcatheter closure of PDA in infants using the ADO is a safe and effective method.
Authors: Carl H Backes; Sharon L Cheatham; Grace M Deyo; Scott Leopold; Molly K Ball; Charles V Smith; Vidu Garg; Ralf J Holzer; John P Cheatham; Darren P Berman Journal: J Am Heart Assoc Date: 2016-02-12 Impact factor: 5.501
Authors: Howaida G El-Said; Andras Bratincsak; Susan R Foerster; Joshua J Murphy; Julie Vincent; Ralf Holzer; Diego Porras; John Moore; Lisa Bergersen Journal: J Am Heart Assoc Date: 2013-11-27 Impact factor: 5.501