Literature DB >> 20032256

Evaluation of diagnostic tests for Clostridium difficile infection.

Jonathan Swindells1, Nigel Brenwald, Nathan Reading, Beryl Oppenheim.   

Abstract

We evaluated toxigenic Clostridium difficile detection by a lateral flow assay for antigen and toxin, an enzyme immunoassay, and two commercial PCR methods. Compared to the cell cytotoxicity neutralization assay and toxigenic culture, both toxin detection methods lacked sensitivity. PCR following combined antigen and toxin detection provided the most useful diagnostic information.

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Year:  2009        PMID: 20032256      PMCID: PMC2815642          DOI: 10.1128/JCM.01579-09

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  14 in total

Review 1.  Clostridium difficile testing: after 20 years, still challenging.

Authors:  Tracy D Wilkins; David M Lyerly
Journal:  J Clin Microbiol       Date:  2003-02       Impact factor: 5.948

2.  Effective detection of toxigenic Clostridium difficile by a two-step algorithm including tests for antigen and cytotoxin.

Authors:  John R Ticehurst; Deborah Z Aird; Lisa M Dam; Anita P Borek; John T Hargrove; Karen C Carroll
Journal:  J Clin Microbiol       Date:  2006-03       Impact factor: 5.948

3.  Evaluation of real-time PCR and conventional diagnostic methods for the detection of Clostridium difficile-associated diarrhoea in a prospective multicentre study.

Authors:  Renate J van den Berg; Norbert Vaessen; Hubert P Endtz; Tanja Schülin; Eric R van der Vorm; Ed J Kuijper
Journal:  J Med Microbiol       Date:  2007-01       Impact factor: 2.472

4.  PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes.

Authors:  S L Stubbs; J S Brazier; G L O'Neill; B I Duerden
Journal:  J Clin Microbiol       Date:  1999-02       Impact factor: 5.948

Review 5.  Laboratory diagnosis of Clostridium difficile-associated diarrhoea: a plea for culture.

Authors:  Michel Delmée; Johan Van Broeck; Anne Simon; Michèle Janssens; Véronique Avesani
Journal:  J Med Microbiol       Date:  2005-02       Impact factor: 2.472

6.  Yield of stool culture with isolate toxin testing versus a two-step algorithm including stool toxin testing for detection of toxigenic Clostridium difficile.

Authors:  Megan E Reller; Clara A Lema; Trish M Perl; Mian Cai; Tracy L Ross; Kathleen A Speck; Karen C Carroll
Journal:  J Clin Microbiol       Date:  2007-09-05       Impact factor: 5.948

7.  Performance of the TechLab C. DIFF CHEK-60 enzyme immunoassay (EIA) in combination with the C. difficile Tox A/B II EIA kit, the Triage C. difficile panel immunoassay, and a cytotoxin assay for diagnosis of Clostridium difficile-associated diarrhea.

Authors:  Heather Snell; Meredith Ramos; Sue Longo; Michael John; Zafar Hussain
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948

8.  Rapid and reliable diagnostic algorithm for detection of Clostridium difficile.

Authors:  Lukas Fenner; Andreas F Widmer; Gisela Goy; Sonja Rudin; Reno Frei
Journal:  J Clin Microbiol       Date:  2007-11-21       Impact factor: 5.948

9.  Laboratory diagnosis of clostridium difficile infection. An evaluation of tests for faecal toxin, glutamate dehydrogenase, lactoferrin and toxigenic culture in the diagnostic laboratory.

Authors:  M W D Wren; M Sivapalan; R Kinson; N R Shetty
Journal:  Br J Biomed Sci       Date:  2009       Impact factor: 3.829

10.  A European survey of diagnostic methods and testing protocols for Clostridium difficile.

Authors:  F Barbut; M Delmée; J S Brazier; J C Petit; I R Poxton; M Rupnik; V Lalande; C Schneider; P Mastrantonio; R Alonso; E Kuipjer; M Tvede
Journal:  Clin Microbiol Infect       Date:  2003-10       Impact factor: 8.067

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  52 in total

1.  The effect of hospital-acquired infection with Clostridium difficile on length of stay in hospital.

Authors:  Alan J Forster; Monica Taljaard; Natalie Oake; Kumanan Wilson; Virginia Roth; Carl van Walraven
Journal:  CMAJ       Date:  2011-12-05       Impact factor: 8.262

2.  Glutamate dehydrogenase for laboratory diagnosis of Clostridium difficile infection.

Authors:  Simon D Goldenberg; Penny R Cliff; Gary L French
Journal:  J Clin Microbiol       Date:  2010-08       Impact factor: 5.948

3.  Laboratory diagnosis of Clostridium difficile infection.

Authors:  S D Goldenberg; P R Cliff; G L French
Journal:  J Clin Microbiol       Date:  2010-08       Impact factor: 5.948

4.  Assessment of Clostridium difficile infections by quantitative detection of tcdB toxin by use of a real-time cell analysis system.

Authors:  Alex B Ryder; Ying Huang; Haijing Li; Min Zheng; Xiaobo Wang; Charles W Stratton; Xiao Xu; Yi-Wei Tang
Journal:  J Clin Microbiol       Date:  2010-08-18       Impact factor: 5.948

5.  The effect of statins on the outcome of Clostridium difficile infection in hospitalized patients.

Authors:  A Atamna; D Yahav; N Eliakim-Raz; E Goldberg; H Ben-Zvi; A Barsheshet; A Elis; J Bishara
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2016-02-10       Impact factor: 3.267

Review 6.  Laboratory diagnosis of Clostridium difficile infection can molecular amplification methods move us out of uncertainty?

Authors:  Fred C Tenover; Ellen Jo Baron; Lance R Peterson; David H Persing
Journal:  J Mol Diagn       Date:  2011-08-18       Impact factor: 5.568

7.  The Daniel K. Inouye College of Pharmacy Scripts: Updates on Clostridium difficile Infection: Advances in Laboratory Testing to Aid Diagnosis and Treatment.

Authors:  Louis Lteif
Journal:  Hawaii J Med Public Health       Date:  2017-02

8.  Laboratory detection of Clostridium difficile in piglets in Australia.

Authors:  Daniel R Knight; Michele M Squire; Thomas V Riley
Journal:  J Clin Microbiol       Date:  2014-08-13       Impact factor: 5.948

Review 9.  Clostridium difficile and inflammatory bowel disease: role in pathogenesis and implications in treatment.

Authors:  Orna Nitzan; Mazen Elias; Bibiana Chazan; Raul Raz; Walid Saliba
Journal:  World J Gastroenterol       Date:  2013-11-21       Impact factor: 5.742

10.  Methods for determining disease burden and calibrating national surveillance data in the United Kingdom: the second study of infectious intestinal disease in the community (IID2 study).

Authors:  Sarah J O'Brien; Greta Rait; Paul R Hunter; James J Gray; Frederick J Bolton; David S Tompkins; Jim McLauchlin; Louise H Letley; Goutam K Adak; John M Cowden; Meirion R Evans; Keith R Neal; Gillian E Smith; Brian Smyth; Clarence C Tam; Laura C Rodrigues
Journal:  BMC Med Res Methodol       Date:  2010-05-05       Impact factor: 4.615

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