Literature DB >> 20026946

Trends in use of opioids for chronic noncancer pain among individuals with mental health and substance use disorders: the TROUP study.

Mark J Edlund1, Bradley C Martin, Andrea Devries, Ming-Yu Fan, Jennifer Brennan Braden, Mark D Sullivan.   

Abstract

OBJECTIVES: Use of prescription opioids for chronic pain is increasing, as is abuse of these medications, though the nature of the link between these trends is unclear. These increases may be most marked in patients with mental health (MH) and substance use disorders (SUDs). We analyzed trends between 2000 and 2005 in opioid prescribing among individuals with noncancer pain conditions (NCPC), with and without MH and SUDs.
METHODS: Secondary data analysis of longitudinal administrative data from 2 dissimilar populations: a national, commercially insured population and Arkansas Medicaid enrollees. We examined these opioid outcomes: (1) rates of any prescription opioid use in the past year, (2) rates of chronic use of prescription opioids (greater than 90 d in the past year), (3) mean days supply of opioids, (4) mean daily opioid dose in morphine equivalents, and (5) percentage of total opioid dose that was Schedule II opioids.
RESULTS: In 2000, among individuals with NCPC, chronic opioid use was more common among those with a MH or SUD than among those without in commercially insured (8% vs. 3%, P<0.001) and Arkansas Medicaid (20% vs. 13%, P<0.001) populations. Between 2000 and 2005, in commercially insured, rates of chronic opioid use increased by 34.9% among individuals with an MH or SUD and 27.8% among individuals without these disorders. In Arkansas Medicaid chronic, opioid use increased by 55.4% among individuals with an MH or SUD and 39.8% among those without. DISCUSSION: Chronic use of prescription opioids for NCPC is much higher and growing faster in patients with MH and SUDs than in those without these diagnoses. Clinicians should monitor the use of prescription opioids in these vulnerable groups to determine whether opioids are substituting for or interfering with appropriate MH and substance abuse treatment.

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Year:  2010        PMID: 20026946      PMCID: PMC2917238          DOI: 10.1097/AJP.0b013e3181b99f35

Source DB:  PubMed          Journal:  Clin J Pain        ISSN: 0749-8047            Impact factor:   3.442


  50 in total

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2.  Potent opioids for chronic musculoskeletal pain: flying blind?

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3.  Opioids and methadone equivalents for clinicians.

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4.  Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.

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5.  Source of drugs for prescription opioid analgesic abusers: a role for the Internet?

Authors:  Theodore J Cicero; Christopher Neil Shores; Alethea G Paradis; Matthew S Ellis
Journal:  Pain Med       Date:  2008-09       Impact factor: 3.750

6.  Association between mental health disorders, problem drug use, and regular prescription opioid use.

Authors:  Mark D Sullivan; Mark J Edlund; Lily Zhang; Jürgen Unützer; Kenneth B Wells
Journal:  Arch Intern Med       Date:  2006-10-23

7.  Pain medication beliefs and medication misuse in chronic pain.

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8.  Treatment needs associated with pain in substance use disorder patients: implications for concurrent treatment.

Authors:  Jodie A Trafton; Elizabeth M Oliva; Doyanne A Horst; Jared D Minkel; Keith Humphreys
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9.  Predicting aberrant drug behavior in patients treated for chronic pain: importance of abuse history.

Authors:  Edward Michna; Edgar L Ross; Wilfred L Hynes; Srdjan S Nedeljkovic; Sharonah Soumekh; David Janfaza; Diane Palombi; Robert N Jamison
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10.  Office visits and analgesic prescriptions for musculoskeletal pain in US: 1980 vs. 2000.

Authors:  Margaret A Caudill-Slosberg; Lisa M Schwartz; Steven Woloshin
Journal:  Pain       Date:  2004-06       Impact factor: 6.961

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  102 in total

1.  Depression and prescription opioid misuse among chronic opioid therapy recipients with no history of substance abuse.

Authors:  Alicia Grattan; Mark D Sullivan; Kathleen W Saunders; Cynthia I Campbell; Michael R Von Korff
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2.  Gender and nonmedical prescription opioid use and DSM-5 nonmedical prescription opioid use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions - III.

Authors:  Bradley T Kerridge; Tulshi D Saha; S Patricia Chou; Haitao Zhang; Jeesun Jung; W June Ruan; Sharon M Smith; Boji Huang; Deborah S Hasin
Journal:  Drug Alcohol Depend       Date:  2015-09-02       Impact factor: 4.492

Review 3.  Pain and Psychology-A Reciprocal Relationship.

Authors:  Nalini Vadivelu; Alice M Kai; Gopal Kodumudi; Karine Babayan; Manuel Fontes; Matthew M Burg
Journal:  Ochsner J       Date:  2017

4.  Prescription Opioid Use and Satisfaction With Care Among Adults With Musculoskeletal Conditions.

Authors:  Brian D Sites; Jordon Harrison; Michael D Herrick; Melissa M Masaracchia; Michael L Beach; Matthew A Davis
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5.  Factors Influencing Long-Term Opioid Use Among Opioid Naive Patients: An Examination of Initial Prescription Characteristics and Pain Etiologies.

Authors:  Anuj Shah; Corey J Hayes; Bradley C Martin
Journal:  J Pain       Date:  2017-07-13       Impact factor: 5.820

6.  Long-term chronic opioid therapy discontinuation rates from the TROUP study.

Authors:  Bradley C Martin; Ming-Yu Fan; Mark J Edlund; Andrea Devries; Jennifer Brennan Braden; Mark D Sullivan
Journal:  J Gen Intern Med       Date:  2011-07-13       Impact factor: 5.128

7.  Negative Affect-Related Factors Have the Strongest Association with Prescription Opioid Misuse in a Cross-Sectional Cohort of Patients with Chronic Pain.

Authors:  Gadi Gilam; John A Sturgeon; Dokyoung S You; Ajay D Wasan; Beth D Darnall; Sean C Mackey
Journal:  Pain Med       Date:  2020-02-01       Impact factor: 3.750

8.  Prescription drug monitoring program inquiry in psychiatric assessment: detection of high rates of opioid prescribing to a dual diagnosis population.

Authors:  Daniel T Hackman; Marion S Greene; Taya J Fernandes; Ashley M Brown; Eric R Wright; R Andrew Chambers
Journal:  J Clin Psychiatry       Date:  2014-07       Impact factor: 4.384

9.  Provider Experiences With the Identification, Management, and Treatment of Co-occurring Chronic Noncancer Pain and Substance Use in the Safety Net.

Authors:  Jamie Suki Chang; Margot Kushel; Christine Miaskowski; Rachel Ceasar; Kara Zamora; Emily Hurstak; Kelly R Knight
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10.  Primary care providers' views on chronic pain management among high-risk patients in safety net settings.

Authors:  Maya Vijayaraghavan; Joanne Penko; David Guzman; Christine Miaskowski; Margot B Kushel
Journal:  Pain Med       Date:  2012-07-30       Impact factor: 3.750

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