Literature DB >> 25093472

Prescription drug monitoring program inquiry in psychiatric assessment: detection of high rates of opioid prescribing to a dual diagnosis population.

Daniel T Hackman, Marion S Greene, Taya J Fernandes, Ashley M Brown, Eric R Wright, R Andrew Chambers1.   

Abstract

OBJECTIVE: An epidemic of prescription drug abuse is disproportionately impacting the mentally ill. We examined the utility of a state prescription drug monitoring database for assessing recent controlled substance prescribing to patients presenting for dual diagnosis treatment.
METHOD: In a community mental health center that provides integrated dual diagnosis care, we queried the Indiana Scheduled Prescription Electronic Collection and Tracking (INSPECT) system for all cases that were open as of August 2, 2011, and had been practitioner-diagnosed (per DSM-IV criteria) by January 2, 2012. INSPECT provided a record of controlled substance dispensations to each patient; diagnostic evaluation was conducted blind from prescription data compilation covering the prior 12 months. Demographic data, insurance status, and DSM-IV diagnoses were compiled from the clinic's electronic medical record.
RESULTS: The sample (N = 201) was 51% female, 56% white, and two-thirds uninsured. Over 80% were dually diagnosed with substance use disorders and psychotic, mood, or anxiety disorders. Nicotine and alcohol disorders were identified in most, with about a third diagnosed with cannabis, cocaine, or opioid disorders. A majority of patients (n = 115) had been prescribed opioids in the prior year, with nearly 1 in 5 prescribed an opioid and benzodiazepine simultaneously. Patients were dispensed a mean of 4 opioid prescriptions and 213 opioid pills. More opioid prescriptions correlated with opioid dependence (OR = 1.08; 95% CI, 1.016-1.145), and more prescribers correlated with personality disorder diagnoses (OR = 1.112; 95% CI, 1.001-1.235). Higher rates and riskier patterns of controlled substance prescribing were identified in patients with Medicaid/Medicare insurance compared to uninsured patients.
CONCLUSIONS: Prescription drug monitoring is a powerful tool for assessing addictions and high frequencies of patient exposures to prescribed opioids in a dual diagnosis clinic. Improved prevention and treatment strategies for addictions as facilitated by more research and clinical use of prescription drug monitoring in psychiatric care are warranted. © Copyright 2014 Physicians Postgraduate Press, Inc.

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Year:  2014        PMID: 25093472      PMCID: PMC4401030          DOI: 10.4088/JCP.14m09020

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  39 in total

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2.  Usefulness of prescription monitoring programs for surveillance--analysis of Schedule II opioid prescription data in Massachusetts, 1996-2006.

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Journal:  Pharmacoepidemiol Drug Saf       Date:  2010-02       Impact factor: 2.890

3.  Mental health disorders and long-term opioid use among adolescents and young adults with chronic pain.

Authors:  Laura P Richardson; Joan E Russo; Wayne Katon; Carolyn A McCarty; Andrea DeVries; Mark J Edlund; Bradley C Martin; Mark Sullivan
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4.  Association between mental health disorders, problem drug use, and regular prescription opioid use.

Authors:  Mark D Sullivan; Mark J Edlund; Lily Zhang; Jürgen Unützer; Kenneth B Wells
Journal:  Arch Intern Med       Date:  2006-10-23

Review 5.  Adult hippocampal neurogenesis in the pathogenesis of addiction and dual diagnosis disorders.

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Journal:  Drug Alcohol Depend       Date:  2012-12-29       Impact factor: 4.492

Review 6.  A neurobiological basis for substance abuse comorbidity in schizophrenia.

Authors:  R A Chambers; J H Krystal; D W Self
Journal:  Biol Psychiatry       Date:  2001-07-15       Impact factor: 13.382

7.  The prevalence of DSM-IV personality disorders in psychiatric outpatients.

Authors:  Mark Zimmerman; Louis Rothschild; Iwona Chelminski
Journal:  Am J Psychiatry       Date:  2005-10       Impact factor: 18.112

8.  Mechanisms of prescription drug diversion among drug-involved club- and street-based populations.

Authors:  James A Inciardi; Hilary L Surratt; Steven P Kurtz; Theodore J Cicero
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Review 9.  Opioid epidemic in the United States.

Authors:  Laxmaiah Manchikanti; Standiford Helm; Bert Fellows; Jeffrey W Janata; Vidyasagar Pampati; Jay S Grider; Mark V Boswell
Journal:  Pain Physician       Date:  2012-07       Impact factor: 4.965

10.  Predictors of resolution of aberrant drug behavior in chronic pain patients treated in a structured opioid risk management program.

Authors:  Salimah H Meghani; Nancy L Wiedemer; William C Becker; Ed J Gracely; Rollin M Gallagher
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  7 in total

1.  High-Risk Prescribing to Medicaid Enrollees Receiving Opioid Analgesics: Individual- and County-Level Factors.

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2.  Medical use, non-medical use and use disorders of benzodiazepines and prescription opioids in adults: Differences by insurance status.

Authors:  Vítor Soares Tardelli; Thiago Marques Fidalgo; Julian Santaella; Silvia S Martins
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3.  Effect of a "pill mill" law on opioid prescribing and utilization: The case of Texas.

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Journal:  Drug Alcohol Depend       Date:  2015-12-31       Impact factor: 4.492

Review 4.  Sleep Management Among Patients with Substance Use Disorders.

Authors:  Subhajit Chakravorty; Ryan G Vandrey; Sean He; Michael D Stein
Journal:  Med Clin North Am       Date:  2018-07       Impact factor: 5.456

Review 5.  Pseudoaddiction: Fact or Fiction? An Investigation of the Medical Literature.

Authors:  Marion S Greene; R Andrew Chambers
Journal:  Curr Addict Rep       Date:  2015-10-01

6.  Prescription drug monitoring program data tracking of opioid addiction treatment outcomes in integrated dual diagnosis care involving injectable naltrexone.

Authors:  Ayesha Sajid; Aaron Whiteman; Richard L Bell; Marion S Greene; Eric A Engleman; R Andrew Chambers
Journal:  Am J Addict       Date:  2016-09-20

7.  Constructing a Real-Time Prescription Drug Monitoring System.

Authors:  Young-Taek Park; Youn Tae Lee; Emmanuel C Jo
Journal:  Healthc Inform Res       Date:  2016-07-31
  7 in total

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