Literature DB >> 2002557

Mutational analysis of the carboxyl terminus of the Moloney murine leukemia virus integration protein.

M J Roth1.   

Abstract

The integration protein (IN) is required for retrovirus DNA integration into the host DNA. The function of the C terminus of the Moloney murine leukemia virus IN protein was examined. The terminal 28 amino acids were found to be nonessential. A linker insertion at position 6025, within a 36-amino-acid insertion not found in any other retrovirus, also produced viable virus.

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Year:  1991        PMID： 2002557      PMCID： PMC240092     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Analysis of mutations in the integration function of Moloney murine leukemia virus: effects on DNA binding and cutting.

Authors:  M J Roth; P Schwartzberg; N Tanese; S P Goff
Journal:  J Virol       Date:  1990-10       Impact factor: 5.103

2.  Insertional mutagenesis of the Abelson murine leukemia virus genome: identification of mutants with altered kinase activity and defective transformation ability.

Authors:  R W Rees-Jones; S P Goff
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

3.  Nucleotide sequence of Moloney murine leukaemia virus.

Authors:  T M Shinnick; R A Lerner; J G Sutcliffe
Journal:  Nature       Date:  1981 Oct 15-21       Impact factor: 49.962

4.  Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase.

Authors:  S Goff; P Traktman; D Baltimore
Journal:  J Virol       Date:  1981-04       Impact factor: 5.103

5.  Construction of mutants of Moloney murine leukemia virus by suppressor-linker insertional mutagenesis: positions of viable insertion mutations.

Authors:  L I Lobel; S P Goff
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

6.  Plaque assay techniques for murine leukemia viruses.

Authors:  W P Rowe; W E Pugh; J W Hartley
Journal:  Virology       Date:  1970-12       Impact factor: 3.616

7.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

8.  Mutants and pseudorevertants of Moloney murine leukemia virus with alterations at the integration site.

Authors:  J Colicelli; S P Goff
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

9.  A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration.

Authors:  L A Donehower; H E Varmus
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

10.  Construction and analysis of deletion mutations in the pol gene of Moloney murine leukemia virus: a new viral function required for productive infection.

Authors:  P Schwartzberg; J Colicelli; S P Goff
Journal:  Cell       Date:  1984-07       Impact factor: 41.582
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  26 in total

1.  Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction.

Authors:  Brandon L Crowe; Ross C Larue; Chunhua Yuan; Sonja Hess; Mamuka Kvaratskhelia; Mark P Foster
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-08       Impact factor: 11.205

2.  Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteins.

Authors:  Jennifer Puglia; Tan Wang; Christine Smith-Snyder; Marie Cote; Michael Scher; Joelle N Pelletier; Sinu John; Colleen B Jonsson; Monica J Roth
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

3.  High-throughput, library-based selection of a murine leukemia virus variant to infect nondividing cells.

Authors:  Julie H Yu; David V Schaffer
Journal:  J Virol       Date:  2006-09       Impact factor: 5.103

4.  Mutational analysis of the envelope gene of Moloney murine leukemia virus.

Authors:  K D Gray; M J Roth
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103

5.  Plasmoviruses: nonviral/viral vectors for gene therapy.

Authors:  P Noguiez-Hellin; M R Meur; J L Salzmann; D Klatzmann
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-30       Impact factor: 11.205

6.  A chimeric Ty3/Moloney murine leukemia virus integrase protein is active in vivo.

Authors:  S L Dildine; J Respess; D Jolly; S B Sandmeyer
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

7.  Ty3 integrase mutants defective in reverse transcription or 3'-end processing of extrachromosomal Ty3 DNA.

Authors:  J Kirchner; S B Sandmeyer
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

8.  Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): naturally selected mutations in IN augment DNA synthesis.

Authors:  Marcus Padow; Lilin Lai; Champion Deivanayagam; Lawrence J DeLucas; Robert B Weiss; Diane M Dunn; Xiaoyun Wu; John C Kappes
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

9.  Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues.

Authors:  P M Cannon; W Wilson; E Byles; S M Kingsman; A J Kingsman
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

10.  Coordinated disintegration reactions mediated by Moloney murine leukemia virus integrase.

Authors:  G A Donzella; C B Jonsson; M J Roth
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103
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