Literature DB >> 20024319

An enzymatic route to 5-deoxy-5-[18F]fluoro-D-ribose, a [18F]-fluorinated sugar for PET imaging.

Mayca Onega1, Juozas Domarkas, Hai Deng, Lutz F Schweiger, Timothy A D Smith, Andrew E Welch, Christophe Plisson, Antony D Gee, David O'Hagan.   

Abstract

An efficient two-step, one-pot, biotransformation involving the fluorinase enzyme is described for the synthesis of 5-deoxy-5-[(18)F]fluororibose, a novel [(18)F]-fluorinated sugar suitable for positron emission tomography (PET) applications.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 20024319     DOI： 10.1039/b919364b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Titania-catalyzed radiofluorination of tosylated precursors in highly aqueous medium.

Authors:  Maxim E Sergeev; Federica Morgia; Mark Lazari; Christopher Wang; R Michael van Dam
Journal:  J Am Chem Soc       Date:  2015-04-22       Impact factor: 15.419

Review 2.  Radiosyntheses using fluorine-18: the art and science of late stage fluorination.

Authors:  Erin L Cole; Megan N Stewart; Ryan Littich; Raphael Hoareau; Peter J H Scott
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295

3.  A coupled chlorinase-fluorinase system with a high efficiency of trans-halogenation and a shared substrate tolerance.

Authors:  H Sun; H Zhao; E L Ang
Journal:  Chem Commun (Camb)       Date:  2018-08-21       Impact factor: 6.222

4.  Identification of 5-Fluoro-5-Deoxy-Ribulose as a Shunt Fluorometabolite in Streptomyces sp. MA37.

Authors:  Linrui Wu; Ming Him Tong; Kwaku Kyeremeh; Hai Deng
Journal:  Biomolecules       Date:  2020-07-10

5.  Characterization of a SAM-dependent fluorinase from a latent biosynthetic pathway for fluoroacetate and 4-fluorothreonine formation in Nocardia brasiliensis.

Authors:  Yaya Wang; Zixin Deng; Xudong Qu
Journal:  F1000Res       Date:  2014-02-19

6.  Biocatalytic synthesis of 2-fluoro-3-hydroxypropionic acid.

Authors:  Wei Liu; Shan Yuan; Miaomiao Jin; Mo Xian
Journal:  Front Bioeng Biotechnol       Date:  2022-08-17
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.