Literature DB >> 20023392

AMPK: A metabolic checkpoint that regulates the growth of EGFR activated glioblastomas.

Deliang Guo, Timothy F Cloughesy, Caius G Radu, Paul S Mischel.   

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Year:  2010        PMID： 20023392      PMCID： PMC3180897          DOI： 10.4161/cc.9.2.10540

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  13 in total

Review 1.  The hallmarks of cancer.

Authors:  D Hanahan; R A Weinberg
Journal:  Cell       Date:  2000-01-07       Impact factor: 41.582

Review 2.  PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors.

Authors:  Ingo K Mellinghoff; Tim F Cloughesy; Paul S Mischel
Journal:  Clin Cancer Res       Date:  2007-01-15       Impact factor: 12.531

3.  Regulation of endothelial cell cycle by laminar versus oscillatory flow: distinct modes of interactions of AMP-activated protein kinase and Akt pathways.

Authors:  Deliang Guo; Shu Chien; John Y-J Shyy
Journal:  Circ Res       Date:  2007-02-01       Impact factor: 17.367

4.  Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies.

Authors:  Jayne M Stommel; Alec C Kimmelman; Haoqiang Ying; Roustem Nabioullin; Aditya H Ponugoti; Ruprecht Wiedemeyer; Alexander H Stegh; James E Bradner; Keith L Ligon; Cameron Brennan; Lynda Chin; Ronald A DePinho
Journal:  Science       Date:  2007-09-13       Impact factor: 47.728

5.  Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation.

Authors:  Bin Zheng; Joseph H Jeong; John M Asara; Yuan-Ying Yuan; Scott R Granter; Lynda Chin; Lewis C Cantley
Journal:  Mol Cell       Date:  2009-01-30       Impact factor: 17.970

6.  The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.

Authors:  Deliang Guo; Isabel J Hildebrandt; Robert M Prins; Horacio Soto; Mary M Mazzotta; Julie Dang; Johannes Czernin; John Y-J Shyy; Andrew D Watson; Michael Phelps; Caius G Radu; Timothy F Cloughesy; Paul S Mischel
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-22       Impact factor: 11.205

7.  AMPK phosphorylation of raptor mediates a metabolic checkpoint.

Authors:  Dana M Gwinn; David B Shackelford; Daniel F Egan; Maria M Mihaylova; Annabelle Mery; Debbie S Vasquez; Benjamin E Turk; Reuben J Shaw
Journal:  Mol Cell       Date:  2008-04-25       Impact factor: 17.970

Review 8.  Therapeutic strategies for inhibiting oncogenic BRAF signaling.

Authors:  Ensar Halilovic; David B Solit
Journal:  Curr Opin Pharmacol       Date:  2008-08-03       Impact factor: 5.547

Review 9.  Understanding the Warburg effect: the metabolic requirements of cell proliferation.

Authors:  Matthew G Vander Heiden; Lewis C Cantley; Craig B Thompson
Journal:  Science       Date:  2009-05-22       Impact factor: 47.728

10.  Comprehensive genomic characterization defines human glioblastoma genes and core pathways.

Authors: 
Journal:  Nature       Date:  2008-09-04       Impact factor: 49.962
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  20 in total

1.  microRNA-29 mediates a novel negative feedback loop to regulate SCAP/SREBP-1 and lipid metabolism.

Authors:  Peng Ru; Deliang Guo
Journal:  RNA Dis       Date:  2017-03-20

2.  An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.

Authors:  Deliang Guo; Felicia Reinitz; Mary Youssef; Cynthia Hong; David Nathanson; David Akhavan; Daisuke Kuga; Ali Nael Amzajerdi; Horacio Soto; Shaojun Zhu; Ivan Babic; Kazuhiro Tanaka; Julie Dang; Akio Iwanami; Beatrice Gini; Jason Dejesus; Dominique D Lisiero; Tiffany T Huang; Robert M Prins; Patrick Y Wen; H Ian Robins; Michael D Prados; Lisa M Deangelis; Ingo K Mellinghoff; Minesh P Mehta; C David James; Arnab Chakravarti; Timothy F Cloughesy; Peter Tontonoz; Paul S Mischel
Journal:  Cancer Discov       Date:  2011-09-15       Impact factor: 39.397

3.  Metformin inhibits leptin-induced growth and migration of glioblastoma cells.

Authors:  Rita Ferla; Eva Haspinger; Eva Surmacz
Journal:  Oncol Lett       Date:  2012-08-03       Impact factor: 2.967

Review 4.  Lipid metabolism emerges as a promising target for malignant glioma therapy.

Authors:  Deliang Guo; Erica Hlavin Bell; Arnab Chakravarti
Journal:  CNS Oncol       Date:  2013-05

Review 5.  Targeting SREBP-1-driven lipid metabolism to treat cancer.

Authors:  Deliang Guo; Erica Hlavin Bell; Paul Mischel; Arnab Chakravarti
Journal:  Curr Pharm Des       Date:  2014       Impact factor: 3.116

6.  Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.

Authors:  William H Chappell; Stephen L Abrams; Richard A Franklin; Michelle M LaHair; Giuseppe Montalto; Melchiorre Cervello; Alberto M Martelli; Ferdinando Nicoletti; Saverio Candido; Massimo Libra; Jerry Polesel; Renato Talamini; Michele Milella; Agostino Tafuri; Linda S Steelman; James A McCubrey
Journal:  Cell Cycle       Date:  2012-11-16       Impact factor: 4.534

7.  Metformin influences progression in diabetic glioblastoma patients.

Authors:  Sebastian Adeberg; Denise Bernhardt; Semi Ben Harrabi; Tilman Bostel; Angela Mohr; Christian Koelsche; Christian Diehl; Stefan Rieken; Juergen Debus
Journal:  Strahlenther Onkol       Date:  2015-09-02       Impact factor: 3.621

8.  SCAP links glucose to lipid metabolism in cancer cells.

Authors:  Deliang Guo
Journal:  Mol Cell Oncol       Date:  2016-01-08

9.  Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.

Authors:  Feng Geng; Xiang Cheng; Xiaoning Wu; Ji Young Yoo; Chunming Cheng; Jeffrey Yunhua Guo; Xiaokui Mo; Peng Ru; Brian Hurwitz; Sung-Hak Kim; Jose Otero; Vinay Puduvalli; Etienne Lefai; Jianjie Ma; Ichiro Nakano; Craig Horbinski; Balveen Kaur; Arnab Chakravarti; Deliang Guo
Journal:  Clin Cancer Res       Date:  2016-06-08       Impact factor: 12.531

10.  Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors.

Authors:  Christopher J Matheson; Kimberly A Casalvieri; Donald S Backos; Mohammed Minhajuddin; Craig T Jordan; Philip Reigan
Journal:  Eur J Med Chem       Date:  2020-04-16       Impact factor: 6.514
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