Literature DB >> 20021994

Family outcomes from a randomized control trial of relapse prevention therapy in first-episode psychosis.

John F M Gleeson1, Sue M Cotton, Mario Alvarez-Jimenez, Darryl Wade, Kingsley Crisp, Belinda Newman, Daniela Spiliotacopoulos, Patrick D McGorry.   

Abstract

OBJECTIVE: We have previously reported that our combined individual and family cognitive-behavioral therapy (CBT) relapse prevention therapy (RPT) was effective in reducing relapse rates compared to treatment as usual (TAU) within a specialist program for young, first-episode psychosis patients who had reached remission on positive symptoms. Here, we report the outcomes for family participants of DSM-IV-diagnosed first-episode psychosis patients recruited between November 2003 and May 2005 over a 2.5-year follow-up period. The primary hypothesis was that, compared to family members receiving TAU, family participants who received RPT would have significantly improved appraisals of stressors related to caregiving. Secondary hypotheses were that RPT would be associated with reduced expressed emotion and improved psychological distress.
METHOD: Family members were assessed at baseline and at 7-month, 12-month, 18-month, 24-month, and 30-month follow-up on appraisal of caregiving, expressed emotion, and psychological distress using the Experience of Caregiving Inventory, The Family Questionnaire, and the General Health Questionnaire of 28 Items, respectively. The family component of RPT was based on family behavioral therapy for schizophrenia with a specific focus on psychoeducation and CBT for relapse prevention.
RESULTS: Thirty-two families received RPT, and 31 families received TAU. There were significant group effects for aspects of the appraisal of caregiving, including negative symptoms, positive personal experiences, and total positive score on the Experience of Caregiving Inventory. Time effects were evident for emotional overinvolvement and for aspects of the appraisal of caregiving. There were no significant effects for psychological distress.
CONCLUSIONS: The relatives of patients who received RPT perceived less stress related to their relative's negative symptoms and an increase in perceived opportunities to make a positive contribution to the care of their relative compared to carers in the TAU condition. Cognitive-behavioral therapy for relapse prevention showed promise in improving the experience of caregiving for family members of first-episode psychosis patients over a 2.5-year follow-up period. TRIAL REGISTRATION: anzctr.org.au Identifier: ACTRN12605000514606. Copyright 2010 Physicians Postgraduate Press, Inc.

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Year:  2009        PMID: 20021994     DOI: 10.4088/JCP.08m04672yel

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  22 in total

1.  Comprehensive early intervention for patients with first-episode psychosis in Japan (J-CAP): study protocol for a randomised controlled trial.

Authors:  Shinsuke Koike; Atsushi Nishida; Syudo Yamasaki; Kayo Ichihashi; Sanae Maegawa; Tatsunobu Natsubori; Hirohiko Harima; Kiyoto Kasai; Izumi Fujita; Masanori Harada; Yuji Okazaki
Journal:  Trials       Date:  2011-06-20       Impact factor: 2.279

2.  A randomized controlled trial of bibliotherapy for carers of young people with first-episode psychosis.

Authors:  Terence V McCann; Dan I Lubman; Sue M Cotton; Brendan Murphy; Kingsley Crisp; Lisa Catania; Claudia Marck; John F M Gleeson
Journal:  Schizophr Bull       Date:  2012-11-20       Impact factor: 9.306

3.  The impact of first episode psychosis on sibling quality of life.

Authors:  Siann Bowman; Mario Alvarez-Jimenez; Darryl Wade; Linsey Howie; Patrick McGorry
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2014-01-22       Impact factor: 4.328

4.  Taking care of the carers: support for families of persons with early psychosis.

Authors:  Cheryl Corcoran
Journal:  World Psychiatry       Date:  2017-10       Impact factor: 49.548

5.  A randomized controlled trial of relapse prevention therapy for first-episode psychosis patients: outcome at 30-month follow-up.

Authors:  John F M Gleeson; Sue M Cotton; Mario Alvarez-Jimenez; Darryl Wade; Donna Gee; Kingsley Crisp; Tracey Pearce; Daniela Spiliotacopoulos; Belinda Newman; Patrick D McGorry
Journal:  Schizophr Bull       Date:  2011-11-29       Impact factor: 9.306

6.  Early psychosis research at Orygen, The National Centre of Excellence in Youth Mental Health.

Authors:  S M Cotton; K M Filia; A Ratheesh; K Pennell; S Goldstone; P D McGorry
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2016-01       Impact factor: 4.328

7.  Caregiver distress in first-episode psychosis: the role of subjective appraisal, over-involvement and symptomatology.

Authors:  Jens Einar Jansen; Ulrik Helt Haahr; Susanne Harder; Anne Marie Trauelsen; Hanne-Grethe Lyse; Marlene Buch Pedersen; Erik Simonsen
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2014-07-23       Impact factor: 4.328

8.  Caregiver Positive and Negative Appraisals: Effects of the National Alliance on Mental Illness Family-to-Family Intervention.

Authors:  Michael J Toohey; Anjana Muralidharan; Deborah Medoff; Alicia Lucksted; Lisa Dixon
Journal:  J Nerv Ment Dis       Date:  2016-02       Impact factor: 2.254

9.  Psychological interventions for psychosis in adolescents.

Authors:  Soumitra S Datta; Rhea Daruvala; Ajit Kumar
Journal:  Cochrane Database Syst Rev       Date:  2020-07-03

10.  Psychosocial interventions for people with both severe mental illness and substance misuse.

Authors:  Glenn E Hunt; Nandi Siegfried; Kirsten Morley; Carrie Brooke-Sumner; Michelle Cleary
Journal:  Cochrane Database Syst Rev       Date:  2019-12-12
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