Literature DB >> 20019353

Commentary: update on animal models for NTP studies.

Angela P King-Herbert1, Robert C Sills, John R Bucher.   

Abstract

Based on recommendations of participants at the National Toxicology Program (NTP) workshop "Animal Models for the NTP Cancer Bioassay: Strains and Stocks-Should We Switch?" some modifications to the NTP rodent cancer bioassay were made. The B6C3F1 remains the mouse model used in the cancer bioassay. The use of multiple strains of mice will be explored through a new branch within the NTP, the Host Susceptibility Branch. Several rat models were evaluated; the Harlan Sprague Dawley rat is currently being used in the NTP studies.

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Year:  2009        PMID： 20019353     DOI： 10.1177/0192623309356450

Source DB:  PubMed          Journal:  Toxicol Pathol        ISSN： 0192-6233            Impact factor:   1.902


  17 in total

1.  Comparison of NTP historical control tumor incidence rates in female Harlan Sprague Dawley and Fischer 344/N Rats.

Authors:  Gregg E Dinse; Shyamal D Peddada; Shawn F Harris; Susan A Elmore
Journal:  Toxicol Pathol       Date:  2010-07-09       Impact factor: 1.902

Review 2.  The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms).

Authors:  Robert R Maronpot; Abraham Nyska; Jennifer E Foreman; Yuval Ramot
Journal:  Crit Rev Toxicol       Date:  2016-06-09       Impact factor: 5.635

3.  Generic Hockey-Stick Model for Estimating Benchmark Dose and Potency: Performance Relative to BMDS and Application to Anthraquinone.

Authors:  Kenneth T Bogen
Journal:  Dose Response       Date:  2010-10-21       Impact factor: 2.658

4.  Proceedings of the 2014 National Toxicology Program Satellite Symposium.

Authors:  Susan A Elmore; Michelle C Cora; Margarita M Gruebbel; Schantel A Hayes; Jessica S Hoane; Haruko Koizumi; Rachel Peters; Thomas J Rosol; Bhanu P Singh; Kathleen A Szabo
Journal:  Toxicol Pathol       Date:  2014-11-09       Impact factor: 1.902

5.  F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfβ Dysregulation.

Authors:  J B Harvey; H-H L Hong; S Bhusari; T-V Ton; Y Wang; J F Foley; S D Peddada; M Hooth; M DeVito; A Nyska; A R Pandiri; M J Hoenerhoff
Journal:  Vet Pathol       Date:  2015-03-02       Impact factor: 2.221

6.  Mammary Gland Evaluation in Juvenile Toxicity Studies: Temporal Developmental Patterns in the Male and Female Harlan Sprague-Dawley Rat.

Authors:  Adam J Filgo; Julie F Foley; Samantha Puvanesarajah; Aditi R Borde; Bentley R Midkiff; Casey E Reed; Vesna A Chappell; Lydia B Alexander; Pretish R Borde; Melissa A Troester; Schantel A Hayes Bouknight; Suzanne E Fenton
Journal:  Toxicol Pathol       Date:  2016-09-09       Impact factor: 1.902

7.  Exome Sequencing of Fresh-frozen or Formalin-fixed Paraffin-embedded B6C3F1/N Mouse Hepatocellular Carcinomas Arising Either Spontaneously or due to Chronic Chemical Exposure.

Authors:  Scott S Auerbach; Miaofei Xu; B Alex Merrick; Mark J Hoenerhoff; Dhiral Phadke; Debra J Taxman; Ruchir Shah; Hue-Hua L Hong; Thai-Vu Ton; Ramesh C Kovi; Robert C Sills; Arun R Pandiri
Journal:  Toxicol Pathol       Date:  2018-07-25       Impact factor: 1.902

8.  Gender differences in chemical carcinogenesis in National Toxicology Program 2-year bioassays.

Authors:  Sandeep Kadekar; Shyamal Peddada; Ilona Silins; John E French; Johan Högberg; Ulla Stenius
Journal:  Toxicol Pathol       Date:  2012-05-14       Impact factor: 1.902

9.  Prenatal and early-life exposure to high-level diesel exhaust particles leads to increased locomotor activity and repetitive behaviors in mice.

Authors:  Keerthi Thirtamara Rajamani; Shannon Doherty-Lyons; Crystal Bolden; Daniel Willis; Carol Hoffman; Judith Zelikoff; Lung-Chi Chen; Howard Gu
Journal:  Autism Res       Date:  2013-03-11       Impact factor: 5.216

10.  Creation and preliminary characterization of a Tp53 knockout rat.

Authors:  Aaron McCoy; Cynthia L Besch-Williford; Craig L Franklin; Edward J Weinstein; Xiaoxia Cui
Journal:  Dis Model Mech       Date:  2012-08-23       Impact factor: 5.758
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