Literature DB >> 20017489

Potato virus X as a novel platform for potential biomedical applications.

Nicole F Steinmetz1, Marianne E Mertens, Rebecca E Taurog, John E Johnson, Ulrich Commandeur, Rainer Fischer, Marianne Manchester.   

Abstract

We demonstrate that nanoparticles formed from the rod-shaped plant virus Potato virus X (PVX) can serve as a novel platform for biomedical applications. Bioconjugation protocols including amine modification and "click" chemistry allowed the efficient functionalization of PVX with biotins, dyes, and PEGs. Fluorescent-labeled and PEGylated PVX particles revealed that different fluorescent labels have a profound effect on PVX-cell interactions. Applying bioconjugation chemistries to PVX opens the door for chemical functionalization with targeting and therapeutic molecules.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20017489      PMCID： PMC2958517          DOI： 10.1021/nl9035753

Source DB:  PubMed          Journal:  Nano Lett        ISSN： 1530-6984            Impact factor:   11.189


  38 in total

Review 1.  Structure-based engineering of an icosahedral virus for nanomedicine and nanotechnology.

Authors:  N F Steinmetz; T Lin; G P Lomonossoff; J E Johnson
Journal:  Curr Top Microbiol Immunol       Date:  2009       Impact factor: 4.291

2.  Digital memory device based on tobacco mosaic virus conjugated with nanoparticles.

Authors:  Ricky J Tseng; Chunglin Tsai; Liping Ma; Jianyong Ouyang; Cengiz S Ozkan; Yang Yang
Journal:  Nat Nanotechnol       Date:  2006-10       Impact factor: 39.213

Review 3.  Plant viruses as biotemplates for materials and their use in nanotechnology.

Authors:  Mark Young; Debbi Willits; Masaki Uchida; Trevor Douglas
Journal:  Annu Rev Phytopathol       Date:  2008       Impact factor: 13.078

4.  Dual-surface modification of the tobacco mosaic virus.

Authors:  Tara L Schlick; Zhebo Ding; Ernest W Kovacs; Matthew B Francis
Journal:  J Am Chem Soc       Date:  2005-03-23       Impact factor: 15.419

5.  Expression of multiple foreign epitopes presented as synthetic antigens on the surface of Potato virus X particles.

Authors:  K Uhde; R Fischer; U Commandeur
Journal:  Arch Virol       Date:  2004-10-20       Impact factor: 2.574

6.  PEGylated viral nanoparticles for biomedicine: the impact of PEG chain length on VNP cell interactions in vitro and ex vivo.

Authors:  Nicole F Steinmetz; Marianne Manchester
Journal:  Biomacromolecules       Date:  2009-04-13       Impact factor: 6.988

7.  Natural supramolecular building blocks. Wild-type cowpea mosaic virus.

Authors:  Qian Wang; Eiton Kaltgrad; Tianwei Lin; John E Johnson; M G Finn
Journal:  Chem Biol       Date:  2002-07

8.  N-Terminal segment of potato virus X coat protein subunits is glycosylated and mediates formation of a bound water shell on the virion surface.

Authors:  Lyudmila A Baratova; Nataliya V Fedorova; Eugenie N Dobrov; Elena V Lukashina; Andrey N Kharlanov; Vitaly V Nasonov; Marina V Serebryakova; Stanislav V Kozlovsky; Olga V Zayakina; Nina P Rodionova
Journal:  Eur J Biochem       Date:  2004-08

Review 9.  Chemistry for peptide and protein PEGylation.

Authors:  M J Roberts; M D Bentley; J M Harris
Journal:  Adv Drug Deliv Rev       Date:  2002-06-17       Impact factor: 15.470

Review 10.  A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors.

Authors:  Ron Hardman
Journal:  Environ Health Perspect       Date:  2006-02       Impact factor: 9.031
View more
  33 in total

1.  A potential nanobiotechnology platform based on infectious bursal disease subviral particles.

Authors:  Omid Taghavian; Manoj K Mandal; Nicole F Steinmetz; Stefan Rasche; Holger Spiegel; Rainer Fischer; Stefan Schillberg
Journal:  RSC Adv       Date:  2012-01-09       Impact factor: 3.361

2.  Transferrin-mediated targeting of bacteriophage HK97 nanoparticles into tumor cells.

Authors:  Rick K Huang; Nicole F Steinmetz; Chi-Yu Fu; Marianne Manchester; John E Johnson
Journal:  Nanomedicine (Lond)       Date:  2011-01       Impact factor: 5.307

3.  Potato virus X, a filamentous plant viral nanoparticle for doxorubicin delivery in cancer therapy.

Authors:  Duc H T Le; Karin L Lee; Sourabh Shukla; Ulrich Commandeur; Nicole F Steinmetz
Journal:  Nanoscale       Date:  2017-02-09       Impact factor: 7.790

4.  Biodistribution and clearance of a filamentous plant virus in healthy and tumor-bearing mice.

Authors:  Sourabh Shukla; Amy M Wen; Nadia R Ayat; Ulrich Commandeur; Ramamurthy Gopalkrishnan; Ann-Marie Broome; Kristen W Lozada; Ruth A Keri; Nicole F Steinmetz
Journal:  Nanomedicine (Lond)       Date:  2013-07-09       Impact factor: 5.307

Review 5.  Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine.

Authors:  Amy M Wen; Pooja H Rambhia; Roger H French; Nicole F Steinmetz
Journal:  J Biol Phys       Date:  2013-04-19       Impact factor: 1.365

6.  Viral nanoparticles as macromolecular devices for new therapeutic and pharmaceutical approaches.

Authors:  Simone Grasso; Luca Santi
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2010-07-06

7.  Engineering of Brome mosaic virus for biomedical applications.

Authors:  Ibrahim Yildiz; Irina Tsvetkova; Amy M Wen; Sourabh Shukla; M Hema Masarapu; Bogdan Dragnea; Nicole F Steinmetz
Journal:  RSC Adv       Date:  2012-01-23       Impact factor: 3.361

Review 8.  Virus-Based Nanoparticles as Versatile Nanomachines.

Authors:  Kristopher J Koudelka; Andrzej S Pitek; Marianne Manchester; Nicole F Steinmetz
Journal:  Annu Rev Virol       Date:  2015-09-25       Impact factor: 10.431

9.  Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X.

Authors:  Karin L Lee; Sourabh Shukla; Mengzhi Wu; Nadia R Ayat; Caroline E El Sanadi; Amy M Wen; John F Edelbrock; Jonathan K Pokorski; Ulrich Commandeur; George R Dubyak; Nicole F Steinmetz
Journal:  Acta Biomater       Date:  2015-03-10       Impact factor: 8.947

10.  A new application of plant virus nanoparticles as drug delivery in breast cancer.

Authors:  Neda Esfandiari; Mohsen Karimi Arzanani; Masoud Soleimani; Mina Kohi-Habibi; Winnie E Svendsen
Journal:  Tumour Biol       Date:  2015-08-19
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.