Literature DB >> 20014782

Total synthesis of the anti-apoptotic agents iso- and bongkrekic acids.

Antoine Francais1, Antonio Leyva, Gorka Etxebarria-Jardi, Steven V Ley.   

Abstract

The first convergent total synthesis of isobongkrekic acid is reported involving three different stereospecific palladium cross-couplings for the formation of the diene units. Access to bongkrekic acid by this route is also demonstrated. These syntheses involve the formation of several potentially general building blocks.

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Year:  2010        PMID： 20014782     DOI： 10.1021/ol902676t

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Catalytic Enantioselective Peroxidation of α,β-Unsaturated Aldehydes for the Asymmetric Synthesis of Biologically Important Chiral Endoperoxides.

Authors:  Lin Hu; Xiaojie Lu; Li Deng
Journal:  J Am Chem Soc       Date:  2015-06-29       Impact factor: 15.419

2.  Nonenzymatic dynamic kinetic resolution of secondary alcohols via enantioselective acylation: synthetic and mechanistic studies.

Authors:  Sarah Yunmi Lee; Jaclyn M Murphy; Atsushi Ukai; Gregory C Fu
Journal:  J Am Chem Soc       Date:  2012-08-30       Impact factor: 15.419

3.  Brønsted acid catalyzed asymmetric propargylation of aldehydes.

Authors:  Pankaj Jain; Hao Wang; Kendall N Houk; Jon C Antilla
Journal:  Angew Chem Int Ed Engl       Date:  2011-12-28       Impact factor: 15.336

4.  Asymmetric Total Synthesis of (-)-Phaeocaulisin A.

Authors:  Áron Péter; Giacomo E M Crisenza; David J Procter
Journal:  J Am Chem Soc       Date:  2022-04-13       Impact factor: 16.383

5.  Diastereo- and enantioselective reactions of bis(pinacolato)diboron, 1,3-enynes, and aldehydes catalyzed by an easily accessible bisphosphine-Cu complex.

Authors:  Fanke Meng; Fredrik Haeffner; Amir H Hoveyda
Journal:  J Am Chem Soc       Date:  2014-08-04       Impact factor: 15.419
  5 in total

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