Literature DB >> 20013090

Prospective study of exclusive strontium-/yttrium-90 beta-irradiation of primary and recurrent pterygia with no prior surgical excision. Clinical outcome of long-term follow-up.

Iraklis Vastardis1, Bojan Pajic, Richard H Greiner, Brigitte Pajic-Eggspuehler, Daniel M Aebersold.   

Abstract

PURPOSE: To evaluate the consecutive treatment results regarding pterygium recurrence and the efficacy of exclusive strontium-/yttrium-90 beta-irradiation for primary and recurrent pterygia and to analyze the functional outcome. PATIENTS AND METHODS: Between October 1974 and December 2005, 58 primary and 21 recurrent pterygia were exclusively treated with strontium-/yttrium-90 beta-irradiation with doses ranging from 3,600 to 5,500 cGy. The follow-up time was 46.6 +/- 26.7 months, with a median of 46.5 months.
RESULTS: The treatment led to a size reduction in all pterygia (p < 0.0001). Neither recurrences nor side effects were observed during therapy and follow-up in this study. Best-corrected visual acuity increased (p = 0.0064). Corneal astigmatism was reduced in recurrent pterygia (p = 0.009).
CONCLUSION: Exclusive strontium-/yttrium-90 beta-irradiation of pterygia is a very efficient and well-tolerated treatment, with remarkable aesthetic and rehabilitative results in comparison to conventional treatments, especially for recurrent lesions which have undergone prior surgical excision.

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Year:  2009        PMID: 20013090     DOI: 10.1007/s00066-009-2000-1

Source DB:  PubMed          Journal:  Strahlenther Onkol        ISSN: 0179-7158            Impact factor:   3.621


  48 in total

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9.  Prospective study on exclusive, nonsurgical strontium-/yttrium-90 irradiation of pterygia.

Authors:  Bojan Pajic; Andreas Pallas; Daniel Aebersold; Guenther Gruber; Richard H Greiner
Journal:  Strahlenther Onkol       Date:  2004-08       Impact factor: 3.621

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  6 in total

1.  [Pterygium. Etiology, clinical aspects and novel adjuvant therapies].

Authors:  L M Heindl; C Cursiefen
Journal:  Ophthalmologe       Date:  2010-06       Impact factor: 1.059

2.  Reirradiation of spinal column metastases: comparison of several treatment techniques and dosimetric validation for the use of VMAT.

Authors:  Florian Stieler; Dirk Wolff; Linda Bauer; Hans-Jörg Wertz; Frederik Wenz; Frank Lohr
Journal:  Strahlenther Onkol       Date:  2011-06-27       Impact factor: 3.621

3.  [The significance of radiation therapy for symptomatic vertebral hemangiomas (SVH)].

Authors:  Reinhard Heyd; M Heinrich Seegenschmiedt; Dirk Rades; Cornelia Winkler; Hans T Eich; Frank Bruns; Georg Gosheger; Normann Willich; Oliver Micke
Journal:  Strahlenther Onkol       Date:  2010-07-29       Impact factor: 3.621

4.  Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study.

Authors:  Bojan Pajic; Daniel M Aebersold; Andreas Eggspuehler; Frederik R Theler; Harald P Studer
Journal:  Sensors (Basel)       Date:  2017-05-24       Impact factor: 3.576

5.  Changes of Corneal Biomechanical Properties upon Exclusive Ytt-/Sr-90 Irradiation of Pterygium.

Authors:  Fritz Rigendinger; Daniel M Aebersold; Zeljka Cvejic; Bojan Pajic
Journal:  Sensors (Basel)       Date:  2021-02-02       Impact factor: 3.576

6.  Portfolio of prospective clinical trials including brachytherapy: an analysis of the ClinicalTrials.gov database.

Authors:  Nikola Cihoric; Alexandros Tsikkinis; Cristina Gutierrez Miguelez; Vratislav Strnad; Ivan Soldatovic; Pirus Ghadjar; Branislav Jeremic; Alan Dal Pra; Daniel M Aebersold; Kristina Lössl
Journal:  Radiat Oncol       Date:  2016-03-22       Impact factor: 3.481

  6 in total

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