Literature DB >> 20012008

[The patient with diabetes in urologic practice: a special risk for lower urinary tract symptoms? Results of the Witten diabetes survey of 4071 type 2 diabetics].

A Wiedemann1, I Füsgen.   

Abstract

Due to demographic developments in industrial nations, age-correlated diseases such as diabetes are becoming more important. In conclusion, lower urinary tract symptoms (LUTS) are a frequent reason for searching treatment by urologists. The association between LUTS and benign prostatic hyperplasia or neurologic diseases is accepted. In contrast there is limited knowledge about the connection of diabetes mellitus and LUTS although an autonomic neuropathy due to diabetes makes urinary bladder dysfunction likely. The following survey covered data of 4071 patients with diabetes type 2 with a medium age of 67,4 years and a diabetes duration of 8,8 years. The incidence of LUTS in diabetic patients increases by increasing age, longer diabetes duration and concomitant diabetes complications e. G. erectile dysfunction. There was a difference in severity of LUTS in patients in urologic treatment or in treatment of a general practitioner: 81,1% of the patients in urologic treatment reported LUTS; in comparison 60,7% of patients being treated by general practitioners complained of LUTS. The LUTS being reported in urologic practice were more severe; e. G. the number of incontinence episodes per week of urologic patients was 7,5, the number of incontinence episodes in general practice 5,7. Lower urinary tract symptoms were most frequently classified as OAB in male patients and classified as mixed incontinence in females. The amount of patients with LUTS was higher in patients with diabetes complications (79,8% vs. 49,9%); there was only a small difference in the number of patients with LUTS stratified by co-medication (64% patients with LUTS without any co-medication; 72% patients with co-medication). The high number of diabetic patients with LUTS in general and urologic practice indicates an underestimation of the problem. LUTS in patients with type-2-diabetes should be screened as eye complications, erectile dysfunction or circulatory disorders by urologists and general practitioners.

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Year:  2010        PMID: 20012008     DOI: 10.1007/s00120-009-2176-0

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  27 in total

1.  Alterations in the formation of cyclic nucleotides and prostaglandins in the lower urinary tract of the diabetic rabbit.

Authors:  F H Mumtaz; C S Thompson; M A Khan; D P Mikhailidis; R J Morgan; G D Angelini; J Y Jeremy
Journal:  Urol Res       Date:  1999-12

2.  Diabetes induced decrease in detrusor smooth muscle force is associated with oxidative stress and overactivity of aldose reductase.

Authors:  Arun K Changolkar; Joseph A Hypolite; Michael Disanto; Peter J Oates; Alan J Wein; Samuel Chacko
Journal:  J Urol       Date:  2005-01       Impact factor: 7.450

3.  [Questionnaire survey on lower urinary tract symptoms (LUTS) for patients attending general practice clinics].

Authors:  Kikuo Okamura; Yoshikatsu Nojiri; Mitate Yamamoto; Mineo Kobayashi; Yoshihito Okamoto; Tadashi Yasui
Journal:  Nihon Ronen Igakkai Zasshi       Date:  2006-07

4.  Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study.

Authors:  Debra E Irwin; Ian Milsom; Steinar Hunskaar; Kate Reilly; Zoe Kopp; Sender Herschorn; Karin Coyne; Con Kelleher; Christian Hampel; Walter Artibani; Paul Abrams
Journal:  Eur Urol       Date:  2006-10-02       Impact factor: 20.096

5.  Glycosylated hemoglobin level and development of mild cognitive impairment or dementia in older women.

Authors:  K Yaffe; T Blackwell; R A Whitmer; K Krueger; E Barrett Connor
Journal:  J Nutr Health Aging       Date:  2006 Jul-Aug       Impact factor: 4.075

6.  Prostaglandin-release impairment in the bladder epithelium of streptozotocin-induced diabetic rats.

Authors:  C Pinna; R Zanardo; L Puglisi
Journal:  Eur J Pharmacol       Date:  2000-02-04       Impact factor: 4.432

7.  Oxidative stress plays a role in diabetes-induced bladder dysfunction in a rat model.

Authors:  Evette Beshay; Serge Carrier
Journal:  Urology       Date:  2004-11       Impact factor: 2.649

8.  Alterations in the nitric oxide synthase binding sites and non-adrenergic, non-cholinergic mediated smooth muscle relaxation in the diabetic rabbit bladder outlet: possible relevance to the pathogenesis of diabetic cystopathy.

Authors:  F H Mumtaz; M E Sullivan; C S Thompson; M R Dashwood; K M Naseem; K R Bruckdorfer; D P Mikhailidis; R J Morgan
Journal:  J Urol       Date:  1999-08       Impact factor: 7.450

9.  Alteration of M(3) subtype muscarinic receptors in the diabetic rat urinary bladder.

Authors:  Yat-Ching Tong; Juei-Tang Cheng
Journal:  Pharmacology       Date:  2002       Impact factor: 2.547

10.  Changed responsiveness of the detrusor in rabbits with alloxan induced hyperglycemia: possible role of 5-hydroxytryptamine for diabetic bladder dysfunction.

Authors:  Nobutaka Ichiyanagi; Toshihiko Tsujii; Hitoshi Masuda; Kazunori Kihara; Moritaka Goto; Hiroshi Azuma
Journal:  J Urol       Date:  2002-07       Impact factor: 7.450

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  2 in total

1.  Overactive bladder in diabetes mellitus patients: a questionnaire-based observational investigation.

Authors:  Giovanni Palleschi; Antonio Luigi Pastore; Cristina Maggioni; Andrea Fuschi; Luca Pacini; Vincenzo Petrozza; Antonio Carbone
Journal:  World J Urol       Date:  2013-10-08       Impact factor: 4.226

2.  [Characteristics of urinary incontinence in the elderly].

Authors:  A Wiedemann; R Anding; R Kirschner-Hermanns
Journal:  Urologe A       Date:  2014-10       Impact factor: 0.639

  2 in total

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