Literature DB >> 25228458

[Characteristics of urinary incontinence in the elderly].

A Wiedemann1, R Anding, R Kirschner-Hermanns.   

Abstract

Geriatric patients are defined as being over 70 years of age and are vulnerable due to multimedication and multimorbidity. The typical incontinence type in geriatric patients is the overactive bladder syndrome as a result of anatomical alterations and the influence of conditions which typically occur in the elderly, e.g. diabetes mellitus, vaginal atrophy, constipation, neurological affections and dementia. This multimorbidity leads to multimedication but many pharmaceutical compounds aimed at indications of diseases distant from the urinary tract can also influence the continence situation. This has been proven for cardiac medications, such as alpha-blockers and diuretics, neurological drug therapy and analgesics. Diagnostic investigations in geriatric patients are usually non-invasive and include geriatric assessment to quantify incontinence symptoms but invasive diagnostic tools are required if the primary therapy fails or an operative intervention is planned. Pharmacotherapy considers the special requirements of the very old patient with cognitive impairment and vulnerability due to falls or delirium. In the group of anticholinergic drugs, trospium chloride seems to be the favorite substance to treat this group of patients because this hydrophilic compound is considered to be unable to cross the blood-brain barrier and therefore minimizes the risk of side effects in the central nervous system (CNS).

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Year:  2014        PMID: 25228458     DOI: 10.1007/s00120-014-3608-z

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  42 in total

1.  Voiding dysfunction and Parkinson's disease: urodynamic abnormalities and urinary symptoms.

Authors:  I Araki; M Kitahara; T Oida; S Kuno
Journal:  J Urol       Date:  2000-11       Impact factor: 7.450

2.  Population-based survey of urinary incontinence, overactive bladder, and other lower urinary tract symptoms in five countries: results of the EPIC study.

Authors:  Debra E Irwin; Ian Milsom; Steinar Hunskaar; Kate Reilly; Zoe Kopp; Sender Herschorn; Karin Coyne; Con Kelleher; Christian Hampel; Walter Artibani; Paul Abrams
Journal:  Eur Urol       Date:  2006-10-02       Impact factor: 20.096

3.  Medically recognized urinary incontinence and risks of hospitalization, nursing home admission and mortality.

Authors:  D H Thom; M N Haan; S K Van Den Eeden
Journal:  Age Ageing       Date:  1997-09       Impact factor: 10.668

4.  Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases.

Authors:  L E Tune; F W Bylsma; D C Hilt
Journal:  J Neuropsychiatry Clin Neurosci       Date:  1992       Impact factor: 2.198

5.  Donepezil overdose: a tenfold dosing error.

Authors:  G Shepherd; W Klein-Schwartz; R Edwards
Journal:  Ann Pharmacother       Date:  1999 Jul-Aug       Impact factor: 3.154

6.  Behavioral therapy to enable women with urge incontinence to discontinue drug treatment: a randomized trial.

Authors:  Kathryn L Burgio; Stephen R Kraus; Shawn Menefee; Diane Borello-France; Marlene Corton; Harry W Johnson; Veronica Mallett; Peggy Norton; Mary P FitzGerald; Kimberly J Dandreo; Holly E Richter; Thomas Rozanski; Michael Albo; Halina M Zyczynski; Gary E Lemack; Toby C Chai; Salil Khandwala; Jan Baker; Linda Brubaker; Anne M Stoddard; Patricia S Goode; Betsy Nielsen-Omeis; Charles W Nager; Kimberly Kenton; Sharon L Tennstedt; John W Kusek; T Debuene Chang; Leroy M Nyberg; William Steers
Journal:  Ann Intern Med       Date:  2008-08-05       Impact factor: 25.391

7.  Severity of urinary incontinence of nursing home residents correlates with malnutrition, dementia and loss of mobility.

Authors:  Achim Rose; Anne Thimme; Carolin Halfar; Hans Georg Nehen; Herbert Rübben
Journal:  Urol Int       Date:  2013-03-08       Impact factor: 2.089

8.  The anticholinergic risk scale and anticholinergic adverse effects in older persons.

Authors:  James L Rudolph; Marci J Salow; Michael C Angelini; Regina E McGlinchey
Journal:  Arch Intern Med       Date:  2008-03-10

9.  Relationship between drug use and urinary incontinence in elderly women.

Authors:  L A Shimp; T J Wells; C A Brink; A C Diokno; G L Gillis
Journal:  Drug Intell Clin Pharm       Date:  1988-10

10.  The effect of angiotensin inhibition on urinary incontinence: data from the National Health and Nutrition Examination Survey (2001-2008).

Authors:  Christopher S Elliott; Craig V Comiter
Journal:  Neurourol Urodyn       Date:  2013-08-29       Impact factor: 2.696

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