Literature DB >> 20011441

Local management of rectal neoplasia.

John Touzios1, Kirk A Ludwig.   

Abstract

The treatment of rectal neoplasia, whether benign or malignant, challenges the surgeon. The challenge in treating rectal cancer is selecting the proper approach for the appropriate patient. In a small number of rectal cancer patients local excision may be the best approach. In an attempt to achieve two goals-cure of disease with a low rate of local failure and maintenance of function and quality of life-multiple approaches can be utilized. The key to obtaining a good outcome for any one patient is balancing the competing factors that impact on these goals. Any effective treatment aimed at controlling rectal cancer in the pelvis must take into account the disease in the bowel wall itself and the disease, or potential disease, in the mesorectum. The major downside of local excision techniques is the potential of leaving untreated disease in the mesorectum. Local management techniques avoid the potential morbidity, mortality, and functional consequences of a major abdominal radical resection and are thus quite effective in achieving the maintenance of function and quality of life goal. The issue for the transanal techniques is how they fare in achieving the first goal-cure of the cancer while keeping local recurrence rates to an absolute minimum. Without removing both the rectum and the mesorectum there is no completely accurate way to determine whether a rectal cancer has moved outside the bowel wall, so any decision on local management of a rectal neoplasm is a calculated risk. For benign neoplasia, the challenge is removing the lesion without having to resort to a major abdominal procedure.

Entities:  

Keywords:  Cancer; neoplasms; rectum; transanal; villous adenoma

Year:  2008        PMID: 20011441      PMCID: PMC2780249          DOI: 10.1055/s-0028-1089945

Source DB:  PubMed          Journal:  Clin Colon Rectal Surg        ISSN: 1530-9681


  49 in total

1.  Local excision of rectal cancer revisited: ACOSOG protocol Z6041.

Authors:  David M Ota; Heidi Nelson
Journal:  Ann Surg Oncol       Date:  2006-11-14       Impact factor: 5.344

2.  Transanal endoscopic microsurgical resection of pT1 rectal tumors.

Authors:  Nadine Duhan Floyd; Theodore J Saclarides
Journal:  Dis Colon Rectum       Date:  2006-02       Impact factor: 4.585

3.  Variables correlated with the risk of lymph node metastasis in early rectal cancer.

Authors:  J T Brodsky; G K Richard; A M Cohen; B D Minsky
Journal:  Cancer       Date:  1992-01-15       Impact factor: 6.860

4.  Conservative treatment of distal rectal cancer by local excision.

Authors:  J J DeCosse; R J Wong; S H Quan; N B Friedman; S S Sternberg
Journal:  Cancer       Date:  1989-01-15       Impact factor: 6.860

5.  High-dose preoperative radiation and full-thickness local excision. A new option for patients with select cancers of the rectum.

Authors:  G Marks; M M Mohiuddin; L Masoni; L Pecchioli
Journal:  Dis Colon Rectum       Date:  1990-09       Impact factor: 4.585

6.  Number and size of lymph nodes and node metastases in rectal carcinomas.

Authors:  O Dworák
Journal:  Surg Endosc       Date:  1989       Impact factor: 4.584

Review 7.  Local excision of rectal carcinoma.

Authors:  R A Graham; L Garnsey; J M Jessup
Journal:  Am J Surg       Date:  1990-09       Impact factor: 2.565

8.  Is the increasing rate of local excision for stage I rectal cancer in the United States justified?: a nationwide cohort study from the National Cancer Database.

Authors:  Y Nancy You; Nancy N Baxter; Andrew Stewart; Heidi Nelson
Journal:  Ann Surg       Date:  2007-05       Impact factor: 12.969

9.  Technique and results of transanal endoscopic microsurgery in early rectal cancer.

Authors:  G Buess; B Mentges; K Manncke; M Starlinger; H D Becker
Journal:  Am J Surg       Date:  1992-01       Impact factor: 2.565

10.  Feasibility and accuracy of TRUS in the pre-treatment staging for rectal carcinoma in general practice.

Authors:  H Ptok; F Marusch; F Meyer; P Wendling; H J C Wenisch; W Sendt; T Manger; H Lippert; I Gastinger
Journal:  Eur J Surg Oncol       Date:  2006-03-06       Impact factor: 4.424

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  3 in total

1.  Oncological outcomes of transanal local excision for high risk T(1) rectal cancers.

Authors:  Ze-Yu Wu; Gang Zhao; Zhe Chen; Jia-Lin Du; Jin Wan; Feng Lin; Lin Peng
Journal:  World J Gastrointest Oncol       Date:  2012-04-15

Review 2.  Endoscopic submucosal dissection versus local excision for early rectal cancer: a systematic review and meta-analysis.

Authors:  S Wang; S Gao; W Yang; S Guo; Y Li
Journal:  Tech Coloproctol       Date:  2015-10-30       Impact factor: 3.781

3.  Giant rectal villous adenoma: Surgical approach with rectal eversion and perianal coloanal anastomosis.

Authors:  Renato Roriz-Silva; Alexei Almeida Andrade; Ivan Gregório Ivankovics
Journal:  Int J Surg Case Rep       Date:  2013-12-17
  3 in total

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