Literature DB >> 2001109

Handwashing and cohorting in prevention of hospital acquired infections with respiratory syncytial virus.

D Isaacs1, H Dickson, C O'Callaghan, R Sheaves, A Winter, E R Moxon.   

Abstract

Hospital acquired infections with respiratory syncytial virus are a major problem. The virus is spread predominantly by infected nasal secretions and we investigated whether we could reduce its incidence by cohorting babies on each ward into designated areas and encouraging staff and parents to wash their hands. We examined the incidence of hospital acquired infection due to respiratory syncytial virus in all children less than 2 years old and in those with congenital heart disease. In 1986-7, before any intervention, 18 (4.2%) of 425 hospitalised children less than 2 years old developed hospital acquired infection due to respiratory syncytial virus. In 1987-8, after intervention, five (0.6%) of 840 children developed hospital acquired infection but there were fewer ward admissions with community acquired infections due to the virus. In 1988-9, when there were more community acquired infections than 1986-7, six (1.1%) of 552 children developed hospital acquired infection. In 1986-7, eight (34.8%) of 23 children less than 2 years old with congenital heart disease developed hospital acquired infection due to respiratory syncytial virus; all eight were among 11 children with congenital heart disease hospitalised for more than 14 days. In 1987-8, one (3.3%) of 30 children with congenital heart disease developed hospital acquired infection due to respiratory syncytial virus and in 1988-9 there was one (2.1%) case out of 47 children with congenital heart disease. Handwashing and cohorting significantly reduce the incidence of nosocomial respiratory syncytial virus infection.

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Year:  1991        PMID: 2001109      PMCID: PMC1792812          DOI: 10.1136/adc.66.2.227

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  14 in total

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Journal:  J Pediatr       Date:  1988-11       Impact factor: 4.406

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Authors:  D Isaacs; C R Bangham; A J McMichael
Journal:  Lancet       Date:  1987-10-03       Impact factor: 79.321

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Journal:  J Infect Dis       Date:  1980-01       Impact factor: 5.226

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Journal:  N Engl J Med       Date:  1975-12-25       Impact factor: 91.245

7.  Respiratory syncytial virus infections in infants: quantitation and duration of shedding.

Authors:  C B Hall; R G Douglas; J M Geiman
Journal:  J Pediatr       Date:  1976-07       Impact factor: 4.406

8.  The use of eye-nose goggles to control nosocomial respiratory syncytial virus infection.

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Journal:  JAMA       Date:  1986-11-21       Impact factor: 56.272

9.  Prevention of nosocomial respiratory syncytial virus infections through compliance with glove and gown isolation precautions.

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Journal:  N Engl J Med       Date:  1987-08-06       Impact factor: 91.245

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Journal:  N Engl J Med       Date:  1986-07-10       Impact factor: 91.245

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  34 in total

1.  2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Health Care Settings.

Authors:  Jane D Siegel; Emily Rhinehart; Marguerite Jackson; Linda Chiarello
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Review 2.  Physical interventions to interrupt or reduce the spread of respiratory viruses.

Authors:  Tom Jefferson; Chris B Del Mar; Liz Dooley; Eliana Ferroni; Lubna A Al-Ansary; Ghada A Bawazeer; Mieke L van Driel; Sreekumaran Nair; Mark A Jones; Sarah Thorning; John M Conly
Journal:  Cochrane Database Syst Rev       Date:  2011-07-06

Review 3.  Bronchiolitis.

Authors:  Thomas Bourke; Michael Shields
Journal:  BMJ Clin Evid       Date:  2011-04-11

Review 4.  Management of acute bronchiolitis.

Authors:  K Rakshi; J M Couriel
Journal:  Arch Dis Child       Date:  1994-11       Impact factor: 3.791

Review 5.  Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs.

Authors:  Günter Kampf; Axel Kramer
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

Review 6.  Bronchiolitis. Origins and optimal management.

Authors:  M L Everard
Journal:  Drugs       Date:  1995-06       Impact factor: 9.546

Review 7.  Epidemiology and prevention of pediatric viral respiratory infections in health-care institutions.

Authors:  D A Goldmann
Journal:  Emerg Infect Dis       Date:  2001 Mar-Apr       Impact factor: 6.883

Review 8.  Clinical relevance of prevention of respiratory syncytial virus lower respiratory tract infection in preterm infants born between 33 and 35 weeks gestational age.

Authors:  X Carbonell-Estrany; L Bont; G Doering; J-B Gouyon; M Lanari
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-07-16       Impact factor: 3.267

Review 9.  Bronchiolitis.

Authors:  Juan Manuel Lozano
Journal:  BMJ Clin Evid       Date:  2007-10-10

Review 10.  Physical interventions to interrupt or reduce the spread of respiratory viruses: systematic review.

Authors:  Tom Jefferson; Chris Del Mar; Liz Dooley; Eliana Ferroni; Lubna A Al-Ansary; Ghada A Bawazeer; Mieke L van Driel; Ruth Foxlee; Alessandro Rivetti
Journal:  BMJ       Date:  2009-09-21
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