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Literature DB >> 20008334

WD40 repeats arrange histone tails for spreading of silencing.

Abstract

Direct binding of WD40 repeat of Embryonic Ectoderm Development (EED) in the Polycomb Repressor Complex 2 (PRC2) to the histone H3 tail regulates the H3K27 methyltrasnferase activity of PRC2. The binding activity is required for the methylation of H3K27 over long distance of a Drosophila chromosome from the UBX (Hox gene) promoter to the PBX upstream enhancer region, implying EED initiates propagation of this repressive mark.

Entities: Gene Species

Mesh：

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Year: 2009 PMID： 20008334 PMCID： PMC6283120 DOI： 10.1093/jmcb/mjp046

Source DB: PubMed Journal: J Mol Cell Biol ISSN： 1759-4685 Impact factor: 6.216

10 in total

Review 1. The diverse functions of histone lysine methylation.

Authors: Cyrus Martin; Yi Zhang
Journal: Nat Rev Mol Cell Biol Date: 2005-11 Impact factor: 94.444

Review 2. Polycomb silencing mechanisms and the management of genomic programmes.

Authors: Yuri B Schwartz; Vincenzo Pirrotta
Journal: Nat Rev Genet Date: 2007-01 Impact factor: 53.242

3. Ring1b-mediated H2A ubiquitination associates with inactive X chromosomes and is involved in initiation of X inactivation.

Authors: Jia Fang; Taiping Chen; Brian Chadwick; En Li; Yi Zhang
Journal: J Biol Chem Date: 2004-10-26 Impact factor: 5.157

Review 4. Spreading of silent chromatin: inaction at a distance.

Authors: Paul B Talbert; Steven Henikoff
Journal: Nat Rev Genet Date: 2006-10 Impact factor: 53.242

5. Diverse functions of WD40 repeat proteins in histone recognition.

Authors: Tamaki Suganuma; Samantha G Pattenden; Jerry L Workman
Journal: Genes Dev Date: 2008-05-15 Impact factor: 11.361

6. Structural basis of histone H4 recognition by p55.

Authors: Ji-Joon Song; Joseph D Garlick; Robert E Kingston
Journal: Genes Dev Date: 2008-04-28 Impact factor: 11.361

7. Imprinted X inactivation maintained by a mouse Polycomb group gene.

Authors: J Wang; J Mager; Y Chen; E Schneider; J C Cross; A Nagy; T Magnuson
Journal: Nat Genet Date: 2001-08 Impact factor: 38.330

8. RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena.

Authors: Yifan Liu; Sean D Taverna; Tara L Muratore; Jeffrey Shabanowitz; Donald F Hunt; C David Allis
Journal: Genes Dev Date: 2007-06-15 Impact factor: 11.361

9. An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.

Authors: Haitao Li; Mohammad R Motamedi; Calvin K Yip; Zhanxin Wang; Thomas Walz; Dinshaw J Patel; Danesh Moazed
Journal: Mol Cell Date: 2009-04-24 Impact factor: 17.970

10. Role of the polycomb protein EED in the propagation of repressive histone marks.

Authors: Raphael Margueron; Neil Justin; Katsuhito Ohno; Miriam L Sharpe; Jinsook Son; William J Drury; Philipp Voigt; Stephen R Martin; William R Taylor; Valeria De Marco; Vincenzo Pirrotta; Danny Reinberg; Steven J Gamblin
Journal: Nature Date: 2009-09-20 Impact factor: 49.962

10 in total

3 in total

1. The ASYMMETRIC LEAVES complex maintains repression of KNOX homeobox genes via direct recruitment of Polycomb-repressive complex2.

Authors: Mukesh Lodha; Cristina F Marco; Marja C P Timmermans
Journal: Genes Dev Date: 2013-03-06 Impact factor: 11.361

2. Direct interaction between the WD40 repeat protein WDR-23 and SKN-1/Nrf inhibits binding to target DNA.

Authors: Chi K Leung; Koichi Hasegawa; Ying Wang; Andrew Deonarine; Lanlan Tang; Johji Miwa; Keith P Choe
Journal: Mol Cell Biol Date: 2014-06-09 Impact factor: 4.272

3. Interaction of SET domains with histones and nucleic acid structures in active chromatin.

Authors: Wladyslaw A Krajewski; Oleg L Vassiliev
Journal: Clin Epigenetics Date: 2011-01-14 Impact factor: 6.551

3 in total