Literature DB >> 20005011

Medication errors recovered by emergency department pharmacists.

Jeffrey M Rothschild1, William Churchill, Abbie Erickson, Kristin Munz, Jeremiah D Schuur, Claudia A Salzberg, Daniel Lewinski, Rita Shane, Roshanak Aazami, John Patka, Rondell Jaggers, Aaron Steffenhagen, Steve Rough, David W Bates.   

Abstract

STUDY
OBJECTIVE: We assess the impact of emergency department (ED) pharmacists on reducing potentially harmful medication errors.
METHODS: We conducted this observational study in 4 academic EDs. Trained pharmacy residents observed a convenience sample of ED pharmacists' activities. The primary outcome was medication errors recovered by pharmacists, including errors intercepted before reaching the patient (near miss or potential adverse drug event), caught after reaching the patient but before causing harm (mitigated adverse drug event), or caught after some harm but before further or worsening harm (ameliorated adverse drug event). Pairs of physician and pharmacist reviewers confirmed recovered medication errors and assessed their potential for harm. Observers were unblinded and clinical outcomes were not evaluated.
RESULTS: We conducted 226 observation sessions spanning 787 hours and observed pharmacists reviewing 17,320 medications ordered or administered to 6,471 patients. We identified 504 recovered medication errors, or 7.8 per 100 patients and 2.9 per 100 medications. Most of the recovered medication errors were intercepted potential adverse drug events (90.3%), with fewer mitigated adverse drug events (3.9%) and ameliorated adverse drug events (0.2%). The potential severities of the recovered errors were most often serious (47.8%) or significant (36.2%). The most common medication classes associated with recovered medication errors were antimicrobial agents (32.1%), central nervous system agents (16.2%), and anticoagulant and thrombolytic agents (14.1%). The most common error types were dosing errors, drug omission, and wrong frequency errors.
CONCLUSION: ED pharmacists can identify and prevent potentially harmful medication errors. Controlled trials are necessary to determine the net costs and benefits of ED pharmacist staffing on safety, quality, and costs, especially important considerations for smaller EDs and pharmacy departments. Copyright (c) 2009 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

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Year:  2009        PMID: 20005011     DOI: 10.1016/j.annemergmed.2009.10.012

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  40 in total

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Review 2.  Tools for Assessing Potential Significance of Pharmacist Interventions: A Systematic Review.

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Journal:  Drug Saf       Date:  2016-02       Impact factor: 5.606

3.  Medication Reconciliation Practices in Canadian Emergency Departments: A National Survey.

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Journal:  Can J Hosp Pharm       Date:  2015 May-Jun

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Journal:  Int J Clin Pharm       Date:  2013-06-21

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Journal:  Eur J Clin Pharmacol       Date:  2014-03-21       Impact factor: 2.953

6.  Analysis of user behavior in accessing electronic medical record systems in emergency departments.

Authors:  Jan Horsky; Matthew B Allen; Allison R Wilcox; Stephanie E Pollard; Pamela Neri; Daniel J Pallin; Jeffrey M Rothschild
Journal:  AMIA Annu Symp Proc       Date:  2010-11-13

7.  Pharmacy and therapeutics committees: leadership opportunities in medication safety for medical toxicologists.

Authors:  Jeanmarie Perrone; Lewis S Nelson
Journal:  J Med Toxicol       Date:  2011-06

8.  Impact of robotic antineoplastic preparation on safety, workflow, and costs.

Authors:  Andrew C Seger; William W Churchill; Carol A Keohane; Caryn D Belisle; Stephanie T Wong; Katelyn W Sylvester; Megan A Chesnick; Elisabeth Burdick; Matt F Wien; Michael C Cotugno; David W Bates; Jeffrey M Rothschild
Journal:  J Oncol Pract       Date:  2012-09-25       Impact factor: 3.840

9.  What are Patients' Concerns about Medical Errors in an Emergency Department?

Authors:  Nahid Kianmehr; Mani Mofidi; Hossein Saidi; Marzieh Hajibeigi; Mahdi Rezai
Journal:  Sultan Qaboos Univ Med J       Date:  2012-02-07

10.  Drug incompatibilities in the adult intensive care unit of a university hospital.

Authors:  Naiane Roveda Marsilio; Daiandy da Silva; Denise Bueno
Journal:  Rev Bras Ter Intensiva       Date:  2016-06
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