Literature DB >> 20000775

Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold.

Wenwen Zhang1, Xiaobao Yang, Weidong Chen, Xiaoyong Xu, Lu Li, Hongbin Zhai, Zhong Li.   

Abstract

Novel neonicotinoid analogues bearing a 1,4-dihydropridine scaffold were designed and synthesized by multicomponent reactions (MCRs) to enhance pi-pi stacking. The synthesized compounds were identified by (1)H NMR, (13)C NMR, high-resolution mass spectroscopy, and elemental analysis. Bioassay tests showed that some of them exhibited high insecticidal activities against pea aphid ( Aphis craccivora ).

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Year:  2010        PMID： 20000775     DOI： 10.1021/jf902034z

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  7 in total

1.  A novel halogen bond and a better-known hydrogen bond cooperation of neonicotinoid and insect nicotinic acetylcholine receptor recognition.

Authors:  Hongxia Duan; Weiwei Zhang; Jin Zhao; Desheng Liang; Xinling Yang; Shuhui Jin
Journal:  J Mol Model       Date:  2012-03-17       Impact factor: 1.810

2.  Molecular recognition of thiaclopride by Aplysia californica AChBP: new insights from a computational investigation.

Authors:  Zakaria Alamiddine; Balaji Selvam; José P Cerón-Carrasco; Monique Mathé-Allainmat; Jacques Lebreton; Steeve H Thany; Adèle D Laurent; Jérôme Graton; Jean-Yves Le Questel
Journal:  J Comput Aided Mol Des       Date:  2015-11-20       Impact factor: 3.686

3.  Synthesis, insecticidal, and antibacterial activities of novel neonicotinoid analogs with dihydropyridine.

Authors:  Yinju He; Deyu Hu; Mingming Lv; Linhong Jin; Jian Wu; Song Zeng; Song Yang; Baoan Song
Journal:  Chem Cent J       Date:  2013-04-26       Impact factor: 4.215

4.  6-[(2-Chloro-pyridin-5-ylmeth-yl)(eth-yl)-azan-yl]-4-(2-fluoro-phen-yl)-1-methyl-5-nitro-1,2,3,4-tetra-hydro-pyridin-2-one.

Authors:  Chuan-Wen Sun; Jing Wang; Ying Wu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-02-17

5.  2-Amino-6-{[(6-chloropyridin-3-yl)methyl](ethyl)amino}-1-methyl-5-nitro-4-phenyl-1,4-dihydro-pyridine-3-carbonitrile ethanol monosolvate.

Authors:  Chuan-Wen Sun; Yan-Xia Chen; Tian-Yan Liu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-03-24

6.  N-{(1Z)-1-[(6-Chloro-pyridin-3-ylmeth-yl)(eth-yl)amino]-3-(3-chloro-phen-yl)-2-nitro-5-oxohex-1-en-yl}-N-methyl-acetamide.

Authors:  Chuan-Wen Sun; Ying Wu; Jing Wang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-10-27

7.  Synthesis and biological activity evaluation of novel β-substituted nitromethylene neonicotinoid analogues.

Authors:  Baozhu Wang; Jiagao Cheng; Zhiping Xu; Xiaoyong Xu; Xusheng Shao; Zhong Li
Journal:  Molecules       Date:  2012-08-24       Impact factor: 4.411
  7 in total

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