Literature DB >> 19962201

Green tea consumption improves endothelial function but not circulating endothelial progenitor cells in patients with chronic renal failure.

Chung Su Park1, Weon Kim2, Jong Shin Woo3, Sang Jin Ha3, Won Yu Kang1, Sun Ho Hwang1, Yong Wook Park4, Yong Sook Kim5, Young Keun Ahn5, Myung Ho Jeong5, Wan Kim1.   

Abstract

This study was designed to determine the effect of green tea consumption in patients with chronic kidney disease (CKD) on flow-mediated endothelium-dependent vasodilation (FMD) and the number of circulating endothelial progenitor cells (EPCs). Forty patients with CKD requiring chronic dialysis were enrolled. The patients were divided into two groups: the catechin group that consumed green tea (5 g/day for 1 month) and the control group that consumed water. The number of EPCs, inflammatory markers, oxidative stress, and FMD were determined at baseline and 4 weeks after green tea consumption. Clinical characteristics, oxidative stress, inflammatory markers, and circulating EPCs number were not significantly different. FMD was significantly improved after 4 weeks in the catechin group (from 5.68±2.67% to 8.66±3.46%, p=0.002). Short-term green tea consumption induced a rapid improvement in FMD, but did not improve circulating EPC levels in patients with CKD.
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

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Year:  2009        PMID: 19962201     DOI: 10.1016/j.ijcard.2009.09.471

Source DB:  PubMed          Journal:  Int J Cardiol        ISSN: 0167-5273            Impact factor:   4.164


  20 in total

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