Literature DB >> 19962041

The importance and features of the distal airways in children and adults.

Erwin W Gelfand1, Monica Kraft.   

Abstract

Asthma remains a major problem worldwide, even with new categories of medications that have been brought into the therapeutic armamentarium. One area of disease pathology and physiology that is involved in the pathobiology of asthma is the distal (small) airways. Better understanding of this area in both the pediatric and adult asthmatic populations will lead to improved targeted therapy for all asthmatic patients. This article discusses the importance of the distal airways for both children and adults with asthma.

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Year:  2009        PMID： 19962041     DOI： 10.1016/j.jaci.2009.07.062

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


  11 in total

1.  Small Airway Targeted Therapy in Pediatric Asthma: Are We There Yet?

Authors:  Hengameh H Raissy; Kathryn Blake
Journal:  Pediatr Allergy Immunol Pulmonol       Date:  2013-12-01       Impact factor: 1.349

2.  Validating CFD Predictions of Pharmaceutical Aerosol Deposition with In Vivo Data.

Authors:  Geng Tian; Michael Hindle; Sau Lee; P Worth Longest
Journal:  Pharm Res       Date:  2015-05-06       Impact factor: 4.200

3.  Elevated levels of NO are localized to distal airways in asthma.

Authors:  John T Anderson; Meiqin Zeng; Qian Li; Ryan Stapley; Doyle Ray Moore; Balachandra Chenna; Naomi Fineberg; Jaroslaw Zmijewski; Isam-Eldin Eltoum; Gene P Siegal; Amit Gaggar; Stephen Barnes; Sadanandan E Velu; Victor J Thannickal; Edward Abraham; Rakesh P Patel; Jack R Lancaster; David D Chaplin; Mark T Dransfield; Jessy S Deshane
Journal:  Free Radic Biol Med       Date:  2011-03-16       Impact factor: 7.376

Review 4.  Are We Meeting the Promise of Endotypes and Precision Medicine in Asthma?

Authors:  Anuradha Ray; Matthew Camiolo; Anne Fitzpatrick; Marc Gauthier; Sally E Wenzel
Journal:  Physiol Rev       Date:  2020-01-09       Impact factor: 37.312

5.  Current Inhalers Deliver Very Small Doses to the Lower Tracheobronchial Airways: Assessment of Healthy and Constricted Lungs.

Authors:  Ross L Walenga; P Worth Longest
Journal:  J Pharm Sci       Date:  2016-01-13       Impact factor: 3.534

Review 6.  Severe asthma in children.

Authors:  Theresa W Guilbert; Leonard B Bacharier; Anne M Fitzpatrick
Journal:  J Allergy Clin Immunol Pract       Date:  2014 Sep-Oct

Review 7.  How to match the optimal currently available inhaler device to an individual child with asthma or recurrent wheeze.

Authors:  Wim M van Aalderen; Luis Garcia-Marcos; Monika Gappa; Warren Lenney; Søren Pedersen; Richard Dekhuijzen; David Price
Journal:  NPJ Prim Care Respir Med       Date:  2015-01-08       Impact factor: 2.871

8.  Distal respiratory tract viral infections in young children trigger a marked increase in alveolar mast cells.

Authors:  Cecilia K Andersson; Medya Shikhagaie; Michiko Mori; Amal Al-Garawi; Jennifer L Reed; Alison A Humbles; Robert Welliver; Thais Mauad; Leif Bjermer; Manel Jordana; Jonas S Erjefält
Journal:  ERJ Open Res       Date:  2018-11-23

9.  Th2-TRMs Maintain Life-Long Allergic Memory in Experimental Asthma in Mice.

Authors:  Berislav Bošnjak; Sahar Kazemi; Lukas M Altenburger; Gordana Mokrović; Michelle M Epstein
Journal:  Front Immunol       Date:  2019-04-24       Impact factor: 7.561

10.  Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study.

Authors:  P E Silkoff; I Strambu; M Laviolette; D Singh; J M FitzGerald; S Lam; S Kelsen; A Eich; A Ludwig-Sengpiel; G C Hupp; V Backer; C Porsbjerg; P O Girodet; P Berger; R Leigh; J N Kline; M Dransfield; W Calhoun; A Hussaini; S Khatri; P Chanez; V S Susulic; E S Barnathan; M Curran; A M Das; C Brodmerkel; F Baribaud; M J Loza
Journal:  Respir Res       Date:  2015-11-17
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