BACKGROUND: To date, no studies have been published that evaluated histomorphometric data from a large number of patients while comparing different sites and methods of autologous bone grafting in sinus floor augmentation procedures. A meta-analysis of the English literature from January 1995 till April 2009 was carried out. MATERIALS AND METHODS: PubMed search engine and the following journals were explored: Clinical Oral Implant Research, International Journal of Oral and Maxillofacial Implants, International Journal of Periodontics and Restorative Dentistry, and the Journal of Periodontology. RESULTS: Out of 147 titles, according to our criteria, 25 articles were left for analysis. The majority were prospective controlled studies (21) and 2 randomized clinical trials, 1 pilot study and 1 case series. A reference value of 47% for total bone volume (TBV) was found while using iliac bone grafting as a standard. Use of intraoral bone grafts increases the TBV, with 11% for chin bone and 14% for bone grafted from other intraoral sites. Particulation of the bone graft has a negative effect on the TBV of 18%. Surprisingly, no correlation between TBV and the time of graft healing was found. Histological section thickness seemed to be a significant variable, as every micron increase of section thickness leads to an increase of 0.4% of TBV. CONCLUSIONS: Bone grafting from the iliac crest resulted in a significantly lower TBV compared with intraoral bone grafting. However, due to the limited availability of intraoral bone to be harvested, iliac grafts still have to be considered the gold standard in augmenting the severely atrophic maxilla.
BACKGROUND: To date, no studies have been published that evaluated histomorphometric data from a large number of patients while comparing different sites and methods of autologous bone grafting in sinus floor augmentation procedures. A meta-analysis of the English literature from January 1995 till April 2009 was carried out. MATERIALS AND METHODS: PubMed search engine and the following journals were explored: Clinical Oral Implant Research, International Journal of Oral and Maxillofacial Implants, International Journal of Periodontics and Restorative Dentistry, and the Journal of Periodontology. RESULTS: Out of 147 titles, according to our criteria, 25 articles were left for analysis. The majority were prospective controlled studies (21) and 2 randomized clinical trials, 1 pilot study and 1 case series. A reference value of 47% for total bone volume (TBV) was found while using iliac bone grafting as a standard. Use of intraoral bone grafts increases the TBV, with 11% for chin bone and 14% for bone grafted from other intraoral sites. Particulation of the bone graft has a negative effect on the TBV of 18%. Surprisingly, no correlation between TBV and the time of graft healing was found. Histological section thickness seemed to be a significant variable, as every micron increase of section thickness leads to an increase of 0.4% of TBV. CONCLUSIONS: Bone grafting from the iliac crest resulted in a significantly lower TBV compared with intraoral bone grafting. However, due to the limited availability of intraoral bone to be harvested, iliac grafts still have to be considered the gold standard in augmenting the severely atrophic maxilla.
Authors: Bálint Trimmel; Noémi Gede; Péter Hegyi; Zsolt Szakács; Gyöngyi Anna Mezey; Eszter Varga; Márton Kivovics; Lilla Hanák; Zoltán Rumbus; György Szabó Journal: Clin Oral Implants Res Date: 2021-01-06 Impact factor: 5.977
Authors: Ivan Valdivia-Gandur; Wilfried Engelke; Víctor Beltrán; Eduardo Borie; Ramón Fuentes; María Cristina Manzanares-Céspedes Journal: Head Face Med Date: 2016-12-01 Impact factor: 2.151
Authors: Eudoxie Pepelassi; Despina Perrea; Ismene Dontas; Christian Ulm; Ioannis Vrotsos; Stefan Tangl Journal: Biomed Res Int Date: 2019-12-14 Impact factor: 3.411
Authors: Paulo José Pasquali; Marcelo Lucchesi Teixeira; Thiago Altro de Oliveira; Luis Guilherme Scavone de Macedo; Antonio Carlos Aloise; André Antonio Pelegrine Journal: Int J Biomater Date: 2015-10-12
Authors: Marco N Helder; Fransisca A S van Esterik; Mardi D Kwehandjaja; Christiaan M Ten Bruggenkate; Jenneke Klein-Nulend; Engelbert A J M Schulten Journal: Clin Oral Implants Res Date: 2018-04-11 Impact factor: 5.977